Antibiotics

Question 1

What is timentin?

Answer 1

Ticarcillin and clavulanic acid (a penicillin)

Question 2

What type of bacterial infection is timentin indicated for?

Answer 2

Gram negatives - particularly Pseudomonas

Question 3

What is the mechanism of action of gentamicin?

Answer 3

Interferes with protein synthesis but binding to 30S and 50S ribosomal subunits

Aminoglycoside

Question 4

What is the major concern with gentamicin use?

Answer 4

Ototoxicity

Question 5

Which bacteria is gentamicin used against?

Answer 5

Many gram negatives

Some Staph aureas

Question 6

What is metronidazole used against?

Answer 6

Anaerobic bacteria and protozoa

Question 7

What is the mechanism of action of metronidazole?

Answer 7

Reduced in anaerobic conditions

Interferes with DNA synthesis

Question 8

What is tazocin?

Answer 8

Combination of piperacillin (penicillin) and tazobactam (beta-lactamase inhibitor)

Question 9

Why might someone with an obstructive jaundice get a coagulopathy?

Answer 9

Vitamin K (fat soluble) malabsorption due fat absorption requiring bile