Chronic Liver Disease

Question 1

Describe the pathological effects on the liver of long-term alcohol ingestion.

Answer 1

Steatosis

Hepatitis

Cirrhosis

Specifically: Fibrosis, Mallory bodies, Fatty change, Hepatocyte necrosis

Question 2

Which of the following morphological changes of chronic alcoholic liver disease are reversible?

Steatosis, Hepatitis, Cirrhosis.

Answer 2

Cirrhosis is irreversible.

Steatosis and Hepatitis are reversible.

Question 3

What are the possible sequelae of cirrhosis?

Answer 3

Portal hypertension.

GIT bleeding, coagulopathy, encephalopathy, hepatorenal syndrome, hepatocellular carcinoma, hepatic failure.

(bold + 3)