Acute inflammation Flashcards
1
Q
What are the three major components of acute inflammation?
A
Vasodilation - increased blood flow
Increased vascular permeability
Migration of leukocytes out of blood vessels
2
Q
How are leukocytes delivered to the site of injury?
A
Margination, rolling, adhesion
Diapedesis (transmigration)
Chemotaxis through interstitium
3
Q
Name some of the chemoattractants responsible for chemotaxis?
A
Bacterial products
C5a
IL-8, Leukotriene B4.
4
Q
What chemical mediators are responsible for pain, fever and tissue damage?
A
IL-1, TNF, Prostaglandins, Bradykinin, and others….
