Chronic Disease Flashcards
Plunked :)
Chronicity
10/10
Palliative approach
Having a meaningful QOL when death is foreseeable
Acute illness
Occurs suddenly without warning
i.e. hemorrhafigic CVA, myocardial infarciton, hip fracture, infection etc.
Chronic illness
Managed rather than cured
Always present but not always visible
Cells have a narrow range of ideal conditions, these include? *
Temp
Hydration
Nutrients
Acid-base balance
Elecotrolytes
Waste?toxicity eolerance
Touch and pressure
Signalling mechanisms such as hormones
If conditions are not ideal for a cell
It will try to adapt
Cell injury can lead to
Disease because cells lose their ability to adapt
4 types of cell injury
Deficit injury (Deficit of water, o2, nutrients, appropriate, temp, adequate waste disposal
Physical injury (result of disruption of intracellular organells = electrical, thermal or mechanical
Infection injury
Toxic (inside or outside the body toxins like alcohol)
Different ways a cell adapts
Short term adaptation
Long-term adaption - Can be unhelpful (smooth muscle atrophy)
Atrophy
Reduction in cell size due to disuese, poor blood flow denervation, malnutrion etc.
Hypertrophy
Enlargement of tissue or organ caused by increased cell size
Hyperplasia
Enlargement of tissue or organ caused by increased rate of cell proliferation
Most common type of hyperplasia
Cancer
Metaplasia (transdifferentiation)
Reversible transformation of one type of adult cell into another type of fully differentiated cell that is less specialized
Is a sign of adaptive response to envormonetal stress
Ducts and bladder epithelial changes in presence of stones
Can be reversed
Dysplasia
Premalignant condition
Abnormal changes in size, number, shape., orientation of cells
May still be reversible in the early stages
Neoplasia
Malignant
Abnormal uncoordinated and excessibe cell growth
Many involve metabolic processes that affect other cells