cholinergic-blocking: chapter 22

Question 1

mechanism of action of cholinergic blocking drugs

Answer 1

block the effects of ach at the receptor

Question 2

effect of cholinergic-blocking drugs on the cv system in low doses

Answer 2

slow hr

Question 3

effect of cholinergic-blocking drugs on the resp system

Answer 3

bronchial dilation

Question 4

effect of cholinergic-blocking drugs on the gi system

Answer 4

decreased gi motility, gi secretions, and salivation

Question 5

effect of cholinergic-blocking drugs on the eye

Answer 5

increased intraocular pressure and cause pupil dilation

Question 6

effect of cholinergic-blocking drugs on the cv system in high doses

Answer 6

block the inhibitory vagal effects on the pacemaker cells of the sa and av nodes which increases hr

Question 7

indication for the use of atropine

Answer 7

management of cardiovascular disorders

Question 8

indications for anticholinergics in terms of the resp system

Answer 8

exercise induced bronchospasm, asthma, copd

Question 9

3 contraindications for anticholinergics

Answer 9

angle closure glaucoma, myasthenia gravis, gi or gu obstruction

Question 10

how is anticholinergic toxicity treated

Answer 10

the stomach should be emptied, activated charcoal to remove the drug from the gi tract that has not been absorbed yet

Question 11

4 severe effects of anticholinergic toxicity

Answer 11

delirium, hallucinations, coma, cardiac dysrhythmia

Question 12

what drug can be used in the case of severe anticholinergic toxicity

Answer 12

physostigmine

Question 13

how can anticholinergics interact with amantadine and antihistamines

Answer 13

additive anticholinergic effects

Question 14

how can anticholinergics interact with phenothiazines

Answer 14

reduce antipsychotic effects

Question 15

how can anticholinergics react with digoxin

Answer 15

increased effects of digoxin

Question 16

what are 5 anticholinergic drugs

Answer 16

atropine, glycopyrrolate, oxybutynin, scopolamine, tolterodine

Question 17

where on the body does atropine have an effect

Answer 17

heart, smooth muscle of the bronchi and intestines

Question 18

indication for glycopyrrolate

Answer 18

control the production of secretions and concentration of free acids in the stomach

Question 19

indication for oxybutynin

Answer 19

treat an overactive bladder

Question 20

indication for scopolamine

Answer 20

prevent motion sickness

Question 21

indication for tolterodine

Answer 21

treat urinary frequency, urgency, and urge incontinence

Question 22

what must be done after administering an anticholinergic via the ophthalamic route

Answer 22

apply light pressure with a tissue to the inner canthus for 30-60 sec

Question 23

what are 3 ways to manage dry mouth caused by anticholinergics

Answer 23

oral care, increase in fluids, sugar free gum or hard candy

Question 24

when should oxybutynin be taken in consideration of meals

Answer 24

1hr before or 2hrs after meals

Question 25

what should be done due to increased sensitivity to light

Answer 25

wear dark or tinted sunglasses