adrenergic: chapter 19 Flashcards
what do a1 receptors on blood vessels do
vasoconstriction
what do b2 receptors on the heart do
increase contractility and hr
what do b2 receptors on blood vessels do
vasodilation
what do b1 receptors on the kidneys do
increase renin secretion
what do b2 receptors on the liver do
glycogenolysis
what do a1 and b2 receptors on gi muscle do
relaxation
what do a1 receptors on the bladder sphincter do
constriction
what do b2 receptors on the uterus do
relaxation
what do b2 receptors son the bronchial muscles do
relaxation
what response do adrenergic drugs produce
sympathetic
what does binding to a1 receptors lead to (2)
vasoconstriction, relaxation
what does stimulation of b1 receptors lead to (4)
positive intotropic, positive chronotropic, positive dromotropic, increase renn secretion
respiratory indications for adrenergic drugs
bronchodilation, asthma, bronchitis, anaphylaxis
indiciations for topical nasal decongestants
dilate arterioles and reduce nasal blood flow
opthalmic indications for adrenergic drugs
vasoconstriction of arterioles, reduce intraocular pressure to treat open angle glaucoma, dilate pupils
cardiovascular indications for adrenergic drugs
support cv system during heart failure or shock
what are 2 serious side effects of adrenergic drugs
seizure, extreme elevation in blood pressure
what drug can be used to control extreme elevations in blood pressure
rapid acting sympatholytic
what receptors does dobutamine target
b1
what effect does dobutamine have on the body
increase cardiac output by increasing contractility (positive inotrophy)
what receptor does dopamine target
b1 and b1
what effect does dopamine have when given at lower infusion rates
dilate blood vessels in the brain, heart, kidneys, and mesentary
what effect does dopamine have when given at higher infusion rates
improve heat contractility and output, cause vasoconstriction
what receptors does epinephrine act on
A and B
how does epinephrine have an effect on b1 receptors
increase the force of contraction and hr
how does epinephrine have an effect on b2 receptors
cause bronchodilation and decrease release of histamine
how does epinephrine have an effect on a1 receptors
cause vasoconstriction which reduces upper airway obstruction, increase bp, and prevent shock
what effect does norepinephrine have on a receptors
vasoconstriction
besides a receptors, what other receptors does norepinephrine stimulate
b1
what receptors does phenylephrine have an effect on
a
indication for the use of phenylephrine
short term treatment to raise bp, control dysrhythmia, and cause vasoconstriction
why may epinephrine not be used in the case of shock
it can cause vasoconstriction of renal vessels leading to possible kidney damage
what is the drug of choice for treating shock. why
norepinephrine because it can cause vasoconstriction of peripheral blood vessels and increase bp without constricting renal vasculature
what order should the patient take their medications if they are prescribed a bronchodilator and a corticosteroid
take the bronchodilator first, wait 5min, then take the corticosteroid
what should be done after taking inhalent forms of adrenergic drugs. why
rinse mouth to prevent irritation and infection
