Cholesterol-CVD drugs Flashcards
1
Q
Name 3 bile acid sequestrants. Describe process.
A
Cholestyramine
Colestipol
Colesevelam
Does not recycle bile back to liver so more dietary cholesterol is used to make new bile.
Lowers LDL
2
Q
2 general types of nicotinic acid. Describe process.
A
Immediate release (crystalline)
Extended release (Niaspanr)
Best at increasing HDL
Stops FFA mobilization so decreases VLDL production.
3
Q
Name 3 fibric acids. Describe process.
A
Gemfibrozil Fenofibrate Clofibrate Increases transcription factor for apo-A and and LPL Lowers TG mostly, raises HDL
4
Q
What is the drug that inhibits cholesterol absorption?
A
Zetia (ezetimibe)
5
Q
Name some HMG-CoA reductase inhibitors. Describe process.
A
Statins family Lovastatin Pravastatin Fluvastatin Simvastatin Atorvastatin Pitava Rosuva Decreases LDL Stops HNG COA reductase enzyme from producing more cholesterol.
