Chapter five, test two Flashcards

(70 cards)

1
Q

what does syntenic mean

A

occurring on same chromosome

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2
Q

what does / mean

A

separate genes found on the two chromosomes of a pair

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3
Q

if the gametes from F1 mother assort independently what is the ratio

A

1:1:1:1

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4
Q

if there is a gamete of 1:1:1:1 ratio from F1 female what are the two possible outcomes

A

parental type and recombinant type

1:1

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5
Q

what is an explanation that the F1 female is more likely to pass on parental combinations of alleles

A

female inhertied wy+ together from p generation mom

inherited w+y together from p generation dad

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6
Q

what shows linked genes

A

parental is greater than recombinant

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7
Q

if the recombinant and parental is 32 and 67 what is the conclusion

A

still linked but not as tight

parental combination alleles travel together more often than not

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8
Q

in mendels dihybrid, how does that work with linkage

A

the gamets dont happen in same ratio or fraction

no longer 9:3:3:1

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9
Q

what is the point of testcross in dihybrid

A

decide if parent is doubly heterozygous

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10
Q

who termed chiasmata

A

Frans janssens

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11
Q

what helped researchers believe recombination occurred

A

physical markers that showed visual abnormalities being transferred

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12
Q

what are genetic markers

A

alleles of genes that could serve as points of reference in determining whether particular progeny were the result of recombination

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13
Q

who came up with the experiment that confirmed the exchange of genetic traits in dihybrids was associated with physical exchange between sister chromatids

A

Curt Stern

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14
Q

physical exchange in allelic recombination

A

need two physical markers to show exchange

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15
Q

what are synaptonemal complexes

A

help homologous chromosomes pair with each other

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16
Q

what is needed to help keep sister chromatids together

A

cohesin

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17
Q

what keeps the homologous chromosomes together at the metaphase plate and thus ensure proper chromosome segregation

A

cohesin

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18
Q

who looked at linked genes

A

thomas hunt morgan

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19
Q

who came up with recombination frequency

A

alfred sturtevant

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20
Q

in a dihybrid with outcome of no cross over meiosis what will the gametes be

A

four parental gametes

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21
Q

what about a single cross over in dihybrid, what are the gametes

A

2 parental

2 recombinant

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22
Q

why is RF= 50% in a dihybrid for genes on nonhomologous chromosomes

A

nonhomologous chromosomes line up randomly to produce all parental or all recombinant in equal freq
meiosis that occur with one crossover bw one gene and centromere generate all four gamete types with equal freq

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23
Q

double cross over 2 strand produces what recombination

A

no recombinants

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24
Q

DCO 3 strand produces what recombination

A

50% recombinants

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25
DCO 4 strand produces what recombination
100% recombinants
26
linked genes mean
must be syntenic and sufficiently close together on same chromosome
27
unlinked genes mean
two genes on different chromosome or two genes on same chromosome but really far apart
28
what are loci
maps that assign genes to specific locations on particular chromosomes
29
what are some limitations of two point crosses
difficult to determine gene order if some gene pairs lie very close together actual distances dont always add up
30
what could be the reason why in a 3 pt cross the distance from a to B and B to C does not equal A to C
double crossover could occur
31
how to correct for double crossover in calculation total distance
count all recombinant numbers and count the dco twice | then divid by total progeny
32
what is chromosomal interference
crossovers not occurring independently of each other
33
what is the coefficient of coincidence
a ratio between the actual frequency of double crossovers observed in an experiment and number of double crossovers expected due to independent probabilities
34
what if interference equals one
no double crossovers occur in experimental progeny because one exchange effectively prevents another
35
what are recombination hotspots
small regions of DNA where the freq of recombination is much higher than average
36
is there recombination occurring during meiosis in male flies
no
37
what is a linkage group
genes chained together by linkage relationships
38
any gene on chromosome is linked to another gene on the same chromosome then what
the number of linkage groups equals the number of pairs of homologous chromosomes in the species
39
what is a chi square test
measures how well observed results conform to predicted ones account for size of experimental population
40
what makes fungus a good species for gametes
they house all four haploid products of each meiosis in an ascus
41
what is the fungus sac calles
ascus
42
what are the haploid cells in ascus called
ascospores
43
the phenotype of haploid fungi is a direct representation of their...
genotype | no complications of dominance
44
meiosis in fungi produces
four haploid ascospores
45
four haploid ascospores generate what in mitosis
8 haploid cells or 4 pairs
46
what do the four pairs in the ascus represent
each pair represents the same genotype because they arose from mitosis
47
can neurospora mate asexually
use during mitosis
48
if neurospora come in opposite mating types what happens
zygote created and goes through mitotic cycles to reproduce
49
what fungi produces unordered tetrads
yeast
50
what fungi produces ordered tetrads
neurospora crassa
51
what does tetrad mean in fungi
4 pairs of 8 haploids in ascus | four products of single meiosis
52
tetrads can by characterized as
parental ditypes nonparental ditypes tetratypes
53
parental ditype is
parental configuration iof alleles
54
what is nonparental ditype
four recombinant spores , two of each type
55
what is tetratype
four different kinds of spores | 2 recombinant and 2 parental
56
how is RF determined in spores
recombinant #/ total number of spores
57
second way to calculate RF
(NPD +1/2 (T))/ total tetrads
58
how to get T tetrad progeny
crossover occurs between only one of the genes and the centromere
59
no cross over produces what ditype
parental
60
single crossover produces what ditype
tetratype
61
double crossover 2 strand produces what ditype
parental
62
DCO 3 strand produces what ditype
tetratype
63
DCO 4 strand produces what ditype
nonparental
64
what is first division segregation pattern (M1)
segregation of two alleles of a single gene at first meiotic division imaginary line drawn between 4th and 5th ascospores cleanly separate haploid showing the two alleles
65
what is second division segregation pattern (M2)
crossover occurs in meiosis one cells with only one kind of allele show up at the end of second meiotic division not cleanly separated
66
how to find mu with ascospores in M2 divisions
(1/2)M2/total tetrads x 100
67
how do twin spots occur
during mitotic recombination
68
what are twin spots
adjacent islands of tissue that differ both from each other and from the tissue surrounding them
69
what is the function behind twin spots
when homozygous recessive phenotype cells are growing next to heterozygous cells showing dominant phenotype
70
how does mitotic recombination occur
homologous chromosomes pair up and non sister chromatids crossover