Chapter 7 Revised Flashcards
Three major circulatory elements
Heart, Blood vessels, blood
Heart generates ____ to drive blood through vessels
Pressure
T/F: Blood flow must meet metabolic demands.
True
Cardiovascular System Major Functions
Delivers O2 and Nutrients
Removes CO2 and other waste
Transports hormones and other molecules
Temperature balance and fluid regulation
Acid-base balance
Immune function
Right side of heart: _____ circulation
Pulmonary
Superior and inferior vena cavae ——>
RA —> tricuspid valve —> RV —> pulmonary valve —> pulmonary arteries —> lungs
Left side of heart: ____ circulation
Systemic
Lungs —>
Pulmonary veins, LA, mitral valve, LV, aortic valve, aorta
What is myocardium?
Cardiac muscle
4 LV characteristics
Must pump blood
Thickest walls
LV hypertrophies with exercise and with disease
But exercise adaptations vs disease adaptations very different
Right coronary artery supplies ___ side of heart
Left (main) coronary artery supplies ___ side of heart
Right
Left
Coronary artery disease
Atherosclerosis
Which muscle type is being described?
- large, long, unbranched, multinucleated
- intermittent, voluntary contractions
- Ca2+ released from SR
Skeletal muscle
Which muscle type is being described?
- Small, short, branched, one nucleus
- Continuous, involuntary rhythmic contractions
- Calcium-induced calcium release
Myocardial cells
Rank the steps of calcium induced calcium release
- DHP receptors in T-tubule are stimulated and open
- AP spreads along sarcolemma down T-tubules
- Extracellular Ca+2 to enter cell, but insufficient to cause contraction
- Instead, triggers ryanodine receptors
AP, DHP, Extracellular, Instead
Myocardial cells fiber type is most similar to type ___ of skeletal muscle.
I
Cardiac muscles fibers connected by regions called _______.
Intercalated discs
Holds cells together
Desmosomes
Rapidly conduct action potentials
Gap junctions
Cardiac muscle has the unique ability to generate its own electrical signal called
Spontaneous rhythmicity
Electrical impulse:
Right atrium —> _______.
Throughout the entire heart
Starting point: ________
Sinoatrial Node
Special cardiac cells generate and spread electrical signal
Spontaneous rhythmicity
Initiates contraction signal
SA node
Delays/relays signal to ventricles
AV node
relays signal to RV,LV
AV bundle (bundle of his)
Send signal into RV,LV
Purkinje fibers
Divides into right and left bundle branches
AV bundle
-Decreases force of contraction
- Decreases HR below intrinsic HR
- Intrinsic HR: 100 beats/min
- Normal Resting HR (RHR): 60 to 100 beats/min
- Elite endurance athlete: 35 beats/min
Parasympathetic
- Increases force of contraction
- Increases HR above intrinsic HR
- Determines HR during physical, emotional stress
- Maximum possible HR: 250 beats/min
Sympathetic
All mechanical and electrical events that occur during one heartbeat
Cardiac cycle
T/F: Diastole is twice as long as systole
True
1/3 of cardiac cycle time
Ventricular systole
2/3 of cardiac cycle time
ventricular diastole
Blood leftover in ventricle =
End-systolic volume
At end, blood in ventricle =
End diastolic volume
Volume of blood pumped in one heartbeat
Stroke volume
% of EDV that was SV
Ejection fraction
Normal ejection fraction for healthy, active young adult at rest
60%
Heart Failure: ___%
40
Total volume of blood pumped per minute
Cardiac Output