Chapter 5 Flashcards
40% of substrate energy is converted into?
ATP
60% of substrate energy is converted to?
Heat
_____ production increases with energy production.
Heat
Heat production can be measured using which measuring device?
Calorimeter
What are the pros of direct calorimetry?
- Directly measures heat
- Accurate for total body energy expenditure over time
Indirect calorimetry is ____ and ______ compared to direct calorimetry.
Easier ; less expensive
Indirect calorimetry estimates total body energy expenditure based on ______ used, ______ produced during __________.
O2, CO2, oxidative phosphorylation
Why is it called indirect calorimetry?
Heat is measured indirectly
Indirect calorimetry is only accurate for __________ metabolism.
Steady-state oxidative
Volume of O2 consumed per minute (VO2) is considered as the rate of _________.
O2 consumption
Volume of CO2 produced per minute (VCO2), it is referred to as the rate of ___________.
CO2 production
What is the atmospheric air composition?
- Nitrogen: 79.03%
- Oxygen: 20.93%
- Other: 1.20%
- CO2: 0.03%
What is the fraction of O2 in inspired air?
0.2093
What is the fraction of CO2 in inspired air?
(0.0003)
What can indirect calorimetry determine?
Substrate utilization
What does O2 usage depend on?
Type of fuel being oxidized
Amount of _____ needed to oxidize a carbohydrate or a fat is proportional to _________ in that substrate.
O2 ; amount of carbon
More carbon atoms in molecule = ________
More O2 needed
Which compound needs more O2? Why?
Glucose: C6H12O6
Palmitic acid (C16H32O2)
Palmitic acid; because it has more carbons which requires more oxygen usage
What is the ratio between rates of CO2 production, O2 usage?
Respiratory exchange ratio (RER)
What is the RER equation?
RER = VCO2/VO2
What is the RER if there are 23O2 & 16 CO2?
0.70
At rest & modern diet, RER is equivalent to what?
0.80
T/F: CO2 production might not = CO2 exhalation.
True
What occurs during Hyperventilation?
Greater CO2 elimination
What occurs during Lactic acid buffering?
Greater non-metabolic CO2
T/F: RER near 1.0 will accurately predict fuel type.
False; it MIGHT not accurately predict fuel type
RER = __________________ / ____________
CO2 produced in metabolism ; O2 consumed