Chapter 7 Flashcards
What genes travel together in meiosis?
linked genes
What are groups of linked genes referred to as?
linkage group
What are gametes that only contain the original combinations of alleles in the parents?
nonrecombinant gametes
What is the kids of parents whose gametes match the combination of the parents?
nonrecombinant progeny
What are gametes with new combination of alleles referred to as?
recombinant gametes
What are the children with new combinations of traits as compared to the parents?
recombinant progeny
What is the percentage of recombinant progeny in a cross?
recombination frequency (# of recombinant/total #)
What is the configuration where both wild-type alleles are found on one chromosome?
coupling configuration or cis configuration
What is the configuration where the wild type alleles are on different chromosomes?
repulsion configuration or trans configuration
Chromosome maps calculated by using recombination
genetic maps
Chromosome maps calculated by using physical distanced.
Physical maps
Distance on genetic maps are measured in…
map units (equals 1% difference in recombination rate)
What is another word for map units?
centiMorgans (cM)
What is a test cross between two genes
Two-point testcross
What is a test cross between three genes
three point testcross
What is the degree to which one crossover interferes with additional crossovers in the same region referred to as?
interference
What value helps us to calculate interference by dividing the observed double crosses by the expected.
coefficient of coincidence
What are the functions that correlate recombination frequencies to actual physical distance
mapping functions
What is the value to determine if genes are actually linked
Lod scores
What are variable genes with easily observable phenotypes
genetic markers
What is the gene mapping strategy where one looks at the progeny phenotypes and looks for associations
linkage analysis
What is the type of gene mapping that looks for nonrandom associations between the presence of a trait and alleles at many different loci.
genome-wide association studies
What is a specific set of linked allleles?
haplotype
what is the nonrandom association between alleles in a haplotype
linkage disequilibrium
What is an area in a genome where individuals vary by a single nucleotide base
single-nucleotide polymorphisms
What is the gene mapping strategy where two different types of cells are fused
somatic-cell hybridization
What is the result of repeated duplication by a viral-infected or cancerous cell
cell line
What is a cell that possesses two nuclei called?
heterokaryon
What is the method for mapping that examines the impact of deletions on phenotype?
deletion mapping
