Chapter 6 The Lymphatic & Immune Systems Flashcards

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1
Q

lymph/o

A

lymph

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2
Q

lymphangi/o

A

lymphatic vessels and ducts

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3
Q

lymphaden/o

A

lymph nodes

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4
Q

tonsill/o, adenoid/o

A

tonsils and adenoids

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5
Q

splen/o

A

spleen

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6
Q

myel/o

A

bone marrow

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7
Q

lymphocyt/o

A

lymphocytes

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8
Q

thym/o

A

thymus

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9
Q

The fluid that removes cellular waste products, pathogens, and dead blood cells from the tissues

A

Lymph

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10
Q

The capillaries, vessels, and ducts that return lymph from the tissues to the venous bloodstream.

A

Lymphatic vessels and ducts

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11
Q

Bean-shaped structures of the lymphatic system where pathogens and other harmful substances are filtered from the lymph by specialized cells of the immune system

A

Lymph Nodes

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12
Q

Lymphoid structures of the lymphatic system that protect the entry to the respiratory system.

A

Tonsils and Adenoids

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13
Q

A sac-like mass of lymphoid tissue with protective roles in both the immune and lymphatic systems.

A

Spleen

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14
Q

Produces lymphocytes

A

Bone Marrow

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15
Q

Specialized leukocytes that play important roles in immune reactions.

A

Lymphocytes

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16
Q

A gland located in the upper chest with specialized roles in both the lymphatic and immune systems.

A

Thymus

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17
Q

anti-

A

against

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18
Q

carcin/o

A

cancerous

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19
Q

immun/o

A

immune, protection, safe

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20
Q

neo-, ne/o

A

new, strange

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21
Q

-oma

A

tumor, neoplasm

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22
Q

onc/o

A

tumor

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23
Q

phag/o

A

eat, swallow

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24
Q

-plasm

A

formative material of cells

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25
Q

sarc/o

A

flesh, connective tissue

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26
Q

-tic

A

pertaining to

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27
Q

tox/o

A

poison, poisonous

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28
Q

What are the 3 main functions of the lymphatic system?

A
  1. Absorb fats and fat-soluble vitamins through the lacteals of the small intestine
  2. Remove waste products from the tissues and cooperate with the immune system in destroying invading pathogens.
  3. Return filtered lymph to the veins at the base of the neck.
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29
Q

What are villi, where are they located, and what do they contain?

A

Small fingerlike projections in the small intestine that contain lacteals and blood vessels.

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30
Q

Specialized structures of the lymphatic system that absorb fats that cannot be transported in the bloodstream. Instead they are transported via lymphatic vessels to venous circulation so they can be used throughout the body as nutrients.

A

Lacteals

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31
Q

Plasma from arterial blood that flows out of the arterioles and into the capillaries, and then flows into the spaces b/w the cells of the tissues. It delivers nutrients, O2, and hormones to cells and takes back waste products and protein molecules that were created within cells. 90% of this fluid returns to bloodstream.

A

Interstitial fluid (aka intercellular or tissue fluid)

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32
Q

A clear, watery fluid containing electrolytes and proteins that makes up 10% of the interstitial fluid and plays role in lymphatic and immune systems.

A

Lymph

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33
Q

Differences in the lymphatic circulatory system

A
  1. Depends on pumping motion of muscles instead of heart
  2. Only flows in one direction- upward until it returns to the circulatory system at the base of the neck.
  3. Lymph is filtered by lymph nodes instead of the kidneys
  4. Not readily visible since it is clear.
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34
Q

Microscopic, sealed on one end tubes located near the surface of the body with capillary walls that are only one cell in thickness. As they close, push lymph upwards.

A

lymphatic capillaries

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35
Q

Where does lymph flow into after lymphatic capillaries?

A

into lymphatic vessels located deeper within tissues

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36
Q

How are lymphatic vessels like veins?

A

The have valves to prevent backflow of lymph

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37
Q

Lymphatic vessels eventually join together to form what?

A

The right lymphatic duct and the thoracic duct

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38
Q

Collects lymph from the right side of the head and neck, the upper right quadrant of the body, and the right arm and empties into the right subclavian vein.

A

Right lymphatic duct

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39
Q

Largest lymphatic vessels of the body that collects lymph from the left side of the head and neck, the upper left quadrant of the trunk, the left arm, lower portion of trunk and legs and empties into the left subclavian vein.

A

thoracic duct

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40
Q

cervic

A

neck

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41
Q

-al

A

pertaining to

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42
Q

axill

A

armpit

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43
Q

-ary

A

pertaining to

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44
Q

inguin

A

groin

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45
Q

Location of cervical lymph nodes.

A

along the sides of the neck

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46
Q

Location of axillary lymph nodes.

A

in armpits

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47
Q

Location of inguinal lymph nodes.

A

the inguinal (groin) area of the lower abdomen

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48
Q

-cytes

A

cells

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49
Q

Where are lymphocytes formed?

A

in bone marrow as stem cells

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50
Q

antigen

A

any substance that the body regards as being foreign (includes viruses, bacteria, toxins, and transplanted tissues)

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51
Q

3 types of lymphcytes

A

Natural killer cells, B cells, T cells

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52
Q

Lymphocytes that play an important role in the killing of cancer cells and cells infected by viruses

A

natural killer cells (NK cells)

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53
Q

Specialized lymphcytes that produce specific antibodies against viruses and bacteria

A

B cells (aka B lymphocytes)

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54
Q

Develop from B cells and secrete a large volume of antibodies coded to detroy specific antigens

A

Plasma cells

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55
Q

Lymphocytes that originate in the thymus that play a role in cell-mediated immunity

A

T cells (aka T lymphocytes)

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56
Q

group of proteins released by T cells that are signals to begin immune response

A

Cytokines

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57
Q

Protein produced in response to mostly viruses and tumor cell antigens and activate the immune system, slow antigen multiplication, and signal other cells

A

Interferons

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58
Q

Protein that plays roles in the immune system, including directing B and T cells to divide and proliferate

A

Interleukins

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59
Q

The masses of lymphoid tissue that form a protective ring around the back of the nose and upper throat

A

tonsils

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60
Q

3 tonsils

A

adenoids, palatine tonsils, lingual tonsils

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61
Q

Tonsils located in the nasopharynx (upper part of pharynx)

A

adenoids (aka naspharyngeal tonsils)

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62
Q

Tonsils located on the left and right sides of the throat

A

palatine tonsils

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63
Q

palatine

A

the hard and soft palates that form the roof of the mouth

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64
Q

Tonsils that are located at the base of the tongue

A

lingual tonsils

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65
Q

Mass of lymphoid tissue located above the heart that secretes a hormone that stimulates the maturation of lymphocytes into T cells

A

thymus (gland)

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66
Q

Hangs from the lower portion of the cecum/large intestine and may play an important role in the immune system

A

the vermiform appendix (aka appendix)

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67
Q

-lytic

A

to destroy

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68
Q

What is the hemolytic function of the spleen?

A

destroys worn-out erythrocytes and releases their hemoglobin for reuse

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69
Q

The immune system’s first line of defense

A
  1. Intact Skin (with it’s acid mantle)
  2. Respiratory system(nose hairs & mucous membranes; tonsils, coughing, sneezing)
  3. Digestive system (acids and enzymes)
  4. Lymphatic system (leukocytes)
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70
Q

Involves binding antigens to antibodies which labels an antigen so it can be recognized and destroyed by other cells of the immune system.

A

antigen-antibody reaction (aka immune reaction)

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71
Q

An acquired unresponsiveness to a specific antigen

A

tolerance

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72
Q

A disease-fighting protein created by the immune system in response to the presence of a specific antigen

A

antibody (aka immunoglobulin)

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73
Q

Most abundant class of antibodies found in blood serum and lymph that are active against bacteria, fungi, viruses, and foreign particles

A

Immunoglobulin G (IgG)

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74
Q

Class of antibodies against ingested antigens found in body secretions.

A

IgA

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75
Q

Class of antibodies found in circulating body fluids first to appear in response to an initial exposure to an antigen

A

IgM

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76
Q

Class of antibodies found only on the surface of B cells for their activation

A

IgD

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77
Q

Class of antibodies produced in lungs, skin, and mucous membranes responsible for allergic reactions

A

IgE

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78
Q

Specialized leukocytes that act as part of the antigen-antibody reaction by destroying substances such as cell debris, dust, pollen, and pathogens by the process of phagocytosis

A

Phagocytes

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79
Q

Phagocytosis

A

the process of destroying pathogens by surrounding and swallowing them

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80
Q

4 kinds of phagocytes

A

Monocytes, macrophages, dendritic cells, mast cells

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81
Q

Leukocytes/phagocytes that provide immunological defenses again many infectious organisms and replenish macrophages and dendritic cells.

A

monocytes

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82
Q

Type of leukocyte/phagocyte the surrounds and kills invading cells

A

macrophage

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83
Q

-phage

A

a cell that eats

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84
Q

Leukocyte/phagocyte that patrols the body searching for antigens, eats it and then alerts the B & T cells to act against this specific antigen

A

dendritic cells

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85
Q

A group of proteins that normally circulate in the blood in an inactive form but when needed complement the ability of antibodies to ward of pathogens

A

the complement system

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86
Q

The state of being resistant to a specific disease

A

immunity

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87
Q

Resistance to a disease present without the administration of an antigen or exposure to a disease

A

natural immunity (passive immunity)

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88
Q

Resistance to a disease by being exposed to it or by getting vaccinated for it

A

Acquired immunity

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89
Q

Medical professional who specializes in diagnosing and treating conditions of altered immunologic reactivity, such as allergic reactions

A

allergist

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90
Q

Specializes in diagnosing and treating disorders of the immune system

A

immunologist

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91
Q

immun

A

protected

92
Q

A physician who specializes in diagnosing and treating disorders of the lymphatic system

A

lymphologist

93
Q

a physician who specializes in diagnosing and treating malignant disorders such as tumors and cancer

A

oncologist

94
Q

Lymphadenitis

A

(aka swollen glands) an inflammation of the lymph nodes

95
Q

Lymphadenopathy

A

any disease process affecting a lymph node or nodes

96
Q

lymphangioma

A

a benign tumor formed by an abnormal collection of lymphatic vessels due to a congenital malformation of the lymphatic system

97
Q

Torn spleen

A

ruptured spleen

98
Q

Splenorrhagia

A

bleeding from the spleen

99
Q

splenomegaly

A

enlargement of the spleen

100
Q

Lymphoscintigraphy

A

test performed to detect damage or malformations of the lymphatic vessels

101
Q

Lymphedema

A

swelling of the tissues due to an abnormal accumulation of lymph fluid within the tissues

102
Q

Primary lymphedema

A

hereditary condition of lymphatic system, usually in females, with feet/leg swelling

103
Q

Secondary lymphedema

A

caused by damage to lymphatic vessels

104
Q

Bioimpedance spectroscopy

A

noninvasive method of diagnosing lymphedema

105
Q

Occurs when the body’s immune system reacts to a harmless allergen such as pollen, food, or animal dander as if it were a dangerous invader

A

allergic reaction

106
Q

An overreaction by the body to a particular antigen

A

allergy (aka hypersensitivity)

107
Q

A substance that produces an allergic reaction in an individual

A

allergen

108
Q

Includes redness, itching and burning where the skin has come in contact with an allergen

A

localized allergic response (aka cellular response)

109
Q

A severe response to an allergen

A

a systemic reaction (aka anaphalaxis)

110
Q

Diagnostic test to identify common allergies

A

scratch test

111
Q

Allergy blood test

A

allergen-specific immunoglobulin E (IgE)

112
Q

Allergy medication

A

antihistamines

113
Q

Any of a large group of disease characterized by a condition in which the immune system produces antibodies against its own tissues, mistaking healthy cells, tissues, or organs for antigens

A

autoimmune disorder/dz

114
Q

Occurs when the immune response is compromised.

A

immunodeficiency disorder

115
Q

An inherited condition in which abnormalities in the immune system cause an increased susceptibility to infection and FTT as a result of infections.

A

severe combined immunodeficiency (SCID)

116
Q

A blood-borne infection in which the virus damages or kills the T cells of the immune system, causing it to progressively fail, thus leaving the body at risk of developing many life-threatening opportunistic infections

A

human immunodefiency virus (HIV)

117
Q

Caused by a pathogen that only produces illness when the host is debilitated

A

opportunistic infection

118
Q

The most advanced and fatal stage of HIV

A

Acquired immunodeficiency syndrome (AIDS)

119
Q

An opportunistic infection frequently associated with HIV that causes patches of abnormal tissue to grow under skin and in lining of mouth, nose, throat or other organs

A

Kaposi’s sarcoma

120
Q

A blood test used to screen for the presence of HIV or Lyme antibodies

A

ELISA (enzyme-linked immunosorbent assay)

121
Q

More accurate test than ELISA to test for HIV

A

western blot test

122
Q

A disease treatment that involves either stimulating (CA) or repressing (allergies) the immune response

A

Immunotherapy (aka biological therapy)

123
Q

Used as a post-exposure preventative measure against certain viruses, including rabies and some types of hepatitis

A

Synthetic immunoglobulins (aka immune serum)

124
Q

Antibody tx used in the treatment of MS, Hep C, and some CA

A

synthetic interferon

125
Q

Any of a class of antibodies produced in the laboratory by identical offspring of a clone of specific cells used to enhance the patient’s immune response to certain maglignancies.

A

Monoclonal antibodies

126
Q

Treatment to repress or interfere w/the ability of the immune system to respond to stimulation by antigens

A

immunosuppression

127
Q

A substance that prevents or reduces the body’s normal immune response

A

immunosuppressant

128
Q

A hormone-like preparation administered primarily as an anti-inflammatory and immunosuppressant.

A

corticosteroid drug

129
Q

a medication the kills or damages cells used as immunosuppressants or antineoplastics

A

cytotoxic drug

130
Q

Pathogen

A

a microorganism that causes a disease in humans

131
Q

A living organism so small it can be seen only with the aid of a microscope

A

microorganism

132
Q

Capable of producing dz

A

pathogenic

133
Q

Bacteria

A

one-celled microscopic organisms

134
Q

Rod-shaped, spore-forming pathogenic bacteria

A

Bacilli

135
Q

A contagious dz that can be tramsmitted through infected livestock and has been used in biological warfare

A

Anthrax

136
Q

A small bacterium that lives in lice, fleas, ticks, and mites that causes Rocky Mountain spotted fever

A

rickettsia

137
Q

Long, slender, spiral shaped bacteria that have flexible walls and are capable of movement

A

Spirochetes

138
Q

Transmitted to humans by the bite of a tick that has had contact with a deer infected w/the spirochete Borrelia burgdoreri

A

Lyme disease

139
Q

Bacteria that form clusters resembling grapes

A

staphylococci

140
Q

staphyl/o

A

clusters or bunches of grapes

141
Q

-cocci

A

spherical bacteria

142
Q

a form of staphyloccus that often infects wounds, causes toxic shock syndrome or food poisening

A

staphylococcus aureus

143
Q

Bacteria that form a chain

A

streptococci

144
Q

Occur when antibiotics fail to kill all of the bacteria they target and the surviving bacteria become restistant to this particular drug

A

antibiotic-resistant bacteria

145
Q

Antibiotic-resistant bacteria with first symptoms of small red bumps that become abscesses

A

Methicillin-resistant Staphylococcus aureus (MRSA)

146
Q

A simple parasitic organism

A

fungus

147
Q

Tinea pedis

A

athlete’s foot

148
Q

A type of fungus

A

Yeast

149
Q

aka yeast infection

A

candidiasis

150
Q

a plant or animal that lives on or within another living organism at the expense of that organism

A

parasite

151
Q

Caused by a parasite that lives in certain mosquitoes and is transferred to humans by the bite of an infected mosquito

A

malaria

152
Q

A parasite that is most commonly transmitted from pets to humans by contact with contaminated animal feces

A

toxoplasmosis

153
Q

Very small infectious agents live only by invading other cells

A

viruses

154
Q

Rare and generally fatal disease transmitted by contact with any bodily fluids infected with this virus. Sx: high fever, vomiting, diarrhea, massive internal bleeding and organ failure

A

Ebola

155
Q

Highly contagious viral respiratory infection. Sx: fever, sore throat, muscle aches, cough, runny nose, fatigue, PNA

A

Influenza (flu)

156
Q

Highly contagious infection that is transmitted by respiratory droplets of the rubeola virus. Sx: red, itchy rash, fever, runny nose, coughing, photophobia

A

Measles

157
Q

An acute viral infection with sx: swelling of parotid glands, ovaries, or testicles

A

mumps

158
Q

A viral infection with sx: low-grade fever, swollen glands, inflamed eyes, fine, pink rash

A

Rubella (aka German measles or three-day measles)

159
Q

Acute viral infection that is transmitted to humans through the bite or saliva of an infected animal

A

rabies

160
Q

spread to humans by the bite of an infected mosquito

A

West Nile virus

161
Q

Type of herpesvirus that is present as a silent infection

A

cytomegalovirus

162
Q

Aka chickenpox

A

varicella

163
Q

aka shingles

A

herpes zoster

164
Q

A complication that may follow herpes zoster if nerve fibers have been damaged

A

postherpetic neuralgia

165
Q

Caused by the Epstein-Barr virus. Sx: fever, sore throat, enlarged lymph nodes, swelling of spleen or liver

A

Infectious mononucleosis (aka mono)

166
Q

bio

A

life

167
Q

Medications capable of inhibiting growth or killing pathogenic bacterial microorganisms

A

antibiotics

168
Q

-cide

A

causing death

169
Q

substance that causes the death of bacteria

A

bactericide

170
Q

-static

A

causing control

171
Q

Slows or stops the growth of bacteria

A

a bacteriostatic agent

172
Q

An agent that destroys or inhibits growth of fungi

A

antifungal (or antimycotic)

173
Q

Used to treat viral infections or to provide temporary immunity

A

an antiviral drug

174
Q

An abnormal growth of body tissue

A

tumor or neoplasm

175
Q

Benign

A

not life-threatening

176
Q

A benign tumor made up of muscle tissue

A

myoma

177
Q

Malignant

A

becoming progressively worse and life-threatening

178
Q

A malignant tumor derived from muscle tissue

A

myosarcoma

179
Q

-genesis

A

reproduction

180
Q

the process through which a tumor supports its growth by creating its own blood supply

A

angiogenesis

181
Q

A form of treatment that disrupts the blood supply to the tumor

A

antiangiogenesis

182
Q

A class of diseases characterized by the uncontrolled division of cells and the ability of these cells to invade other tissues

A

Cancer

183
Q

To spread from one place to another

A

metastasize

184
Q

The process by which cancer is spread to a new site, and the term is also used to describe the tumor itself

A

Metastasis

185
Q

A malignant tumor that occurs in epithelial tissue

A

carcinoma

186
Q

A malignant tumor in its original position that has not yet disturbed or invaded the surrounding tissue

A

carcinoma in situ

187
Q

Any one of a large group of carcinomas derived from glandular tissue

A

adenocarcinoma

188
Q

A malignant tumor that arises from connective tissues

A

sarcoma

189
Q

A hard-tissue sarcoma that usually involves the upper shaft of the long bones, pelvis, or knee

A

osteosarcoma

190
Q

A tumor of the tissues surrounding a synovial joint

A

synovial sarcoma

191
Q

A cancer of the white blood-forming cells in the bone marrow

A

leukemia

192
Q

The process of classifying tumors by how far the disease has progressed

A

staging

193
Q

A general term applied to malignancies affecting lymphoid tissue

A

lymphoma

194
Q

A cancer of the immune system distinguished by the presence of large, cancerous lymphcytes known a Reed-Sternberg cells

A

Hodgkin’s lymphoma

195
Q

Refers to all lymphomas other than Hodkin’s lymphoma

A

Non-Hodgkin’s lymphoma

196
Q

Breast cancer

A

a carcinoma that develops from the cells of the breast and can spread to adjacent lymph nodes and other body sites

197
Q

Ductal carcinoma in situ (DCIS)

A

breast cancer at the earlies stage before the cancer has broken through the wall of the milk duct

198
Q

Infiltrating ductal carcinoma (IDC)

A

breast ca that starts in the milk duct and invades the fatty breast tissue outside the duct.

199
Q

Inflammatory breast cancer (IBC)

A

Aggressive form of breast ca in which the cancer cells block the lymphatic vessels in the skin of the breast.

200
Q

A radiographic examination of the breasts to detect the presence of tumors or precancerous cells

A

mammography

201
Q

A nuclear medicine technique using gamma radiation to detect potential tumors in dense breast tissue

A

Molecular breast imaging (MBI)

202
Q

Often used as an initial f/u test for an abnormal mammogram

A

ultrasound

203
Q

Uses magnets and radio waves and iv contrast medium to get more detailed information of breast

A

breast MRI

204
Q

A technique in which an x-ray or MRI guided needle is used to remove small samples of tissue from the breast

A

needle breast biopsy

205
Q

bi-

A

pertaining to life

206
Q

-opsy

A

view of

207
Q

the removal of a small piece of tissue for examination to confirm a diagnosis

A

surgical biopsy

208
Q

A surgical procedure in which all of the lymph nodes in a major group are removed to determine or slow the spread of cancer in this area

A

lymph node dissection

209
Q

lumpectomy

A

the surgical removal of only the cancerous tissue with the surrounding margin of normal tissue

210
Q

mastectomy

A

the surgical removal of the entire breast and nipple

211
Q

mast

A

breast

212
Q

The surgical removal of an entire breast and many of the surrounding tissues

A

radical mastectomy

213
Q

The surgical removal of the entire breast and all of the axillary lymph nodes under the adjacent arm

A

modified radical mastectomy

214
Q

The use of chemical agents and drugs in combinations selected to destroy malignant cells and tissues

A

chemotherapy

215
Q

The use of natural or synthetic substances such as drugs or vitamins to reduce the risk of developing

A

chemoprevention

216
Q

a medication that blocks the development, growth, or proliferation of malignant cells

A

antineoplastic

217
Q

Used in the treatment in some cancers with the goal of destroying only the cancerous tissues

A

radiation therapy

218
Q

The use of radioactive materials in contact with the tissues to be treated

A

Brachytherapy

219
Q

brachy-

A

short

220
Q

tele-

A

distant

221
Q

Radiation therapy administered at a distance from the body

A

teletherapy

222
Q

tom/o

A

slice

223
Q

Combines tomography and radiation therapy to precisely target the tumor being treated

A

Tomotherapy

224
Q

A developing form of anticancer drug therapy that uses drugs to identify and attack CA cells w/o harming normal cells

A

Targeted therapy

225
Q

Sometimes used after the primary cancer treatments have been completed to decrease the chance that cancer will recur.

A

Adjuvant therapy

226
Q

Involve testing new and promising cancer treatments that have not yet received FDA approval

A

Clinical trials