Chapter 6: 6.13 Eukaryotic Post-Transcriptional Regulation

Question 1

Define:

Splicing

Answer 1

Removal of segments of RNA
* A form of post-transcriptional regulation

Question 2

What are normally removed in splicing?

Answer 2

Introns are removed
Exons remain to be expressed

Question 3

Define:

Alternative Splicing

Answer 3

Splicing where some exons can be removed to yield different proteins from the same RNA transcript

Question 4

True or False:

RNA will not be degraded

Answer 4

False, RNA will inevitably still be degraded

Question 5

If RNA degrades very quickly, it is ——– and little ——- can be produced from it

Answer 5

• Unstable
• Protein

Question 6

Define:

RNA-binding proteins (RBPs)

Answer 6

Can bind to RNA to control stability

Question 7

Where do RBPs bind to specifically in the RNA?

Answer 7

The untranslated regions (UTRs)

Question 8

Define:

MicroRNAs (miRNAs)

Answer 8

Short RNAs that can bind to protein-coding RNA to block translation or tag it for destruction by the RNA-induced silencing complex (RISC)

Question 9

What is Short Interfering RNAs (siRNAs)?

Answer 9

Work similar to miRNAs