Chapter 10: 10.5 Genetic Linkage Flashcards
Genes follow the Law of Independent Assortment when they are located…
- On different chromosomes
- Far apart on the same chromosome
When genes ore located close together on the same chromosomes, they are said to be…
Linked
When genes are located very close together, the chance of recombination occurring between them is…
Low
What are recombination frequencies used for?
Used to determine how close together two genes are on the same chromosome
What is done to determine recombination frequencies?
A cross is done using:
1. A fly that is heterozygous for both genes of interest
2. A fly that is homozygous recessive for both genes of interest
The heterozygous individual will therefore completely determine the phenotype of the offspring
What is the formula for calculating recombination frequency?
RF = (Recombinants / Total offspring) * 100%
What do linker maps determine?
Relative distance and order of genes on a chromosome
What is used to create a linkage map?
Use the recombination frequency to determine how close together genes are located on chromosome
What is one percent equal to in a linkage map?
One centimorgan