Chapter 2: 2.2 Genomic Mapping

Question 1

Define:

Genome mapping

Answer 1

The process of finding the positions (locations) of genes on chromosomes

Question 2

What does gene mapping start with? Why?

Answer 2

Linkage analysis
* To determine which genes are close together (linked)

Question 3

True or False:

Different alleles of the same gene give same phenotypes

Answer 3

False, they give different phenotypes

Question 4

Do different alleles have different DNA sequences?

Answer 4

Yes

Question 5

State the relation between:

• Gene mapping
• Allele
• Phenotype

Answer 5

Gene mapping can be done to determine which allele gives a particular phenotype

Question 6

Define:

SNPs

Answer 6

Single Nucleotide Polymorphisms
* Single base pair changes in the gene

Question 7

Define:

RFLPs

Answer 7

Restriction Fragment Length Polymorphisms
* Occur when the genome is digested with restriction enzymes
* A SNP that occurs in the specific restriction site so that the restriction enzyme can no longer cut at that particular location

Question 8

How can different allees be identified?

Answer 8

1. SNPs
2. RFLPs

Question 9

Different alleles will result in…

Answer 9

Different band pattern on an electrophoresis gel