Chapter 6 Flashcards

0
Q

Adipocytes can be found in

A

Found isolated
In small groups
Within loose or irregular connective tissue
( aggregates is called fat)

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1
Q

Another name for fat cells

A

Adipocytes

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2
Q

The caloric density of ___________ is twice that of proteins ( 9.3 kcal/g) is twice that of proteins or carbohydrates
Most efficient form of nutrient storage

A

Triglycerides

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3
Q

Adipose cells where the triglycerides are stored in a single huge droplet of lipid that almost fills the entire cell

A

Unilocular

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4
Q

Have one very large droplet of whitish yellow fat in the it’s cytoplasm

A

White adipose tissue

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5
Q

Contains cells with multiple lipid droplets interspersed among abundant mitochondria which gives these cells a darker appearance

A

Brown adipose tissue

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6
Q

When unilocular adipocytes can generate benign tumors called

A

Lipomas

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7
Q

Malignant adipose tumors

A

Liposarcomas

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8
Q

Fetal lipomas of brown fat are sometimes called

A

Hibernomas

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9
Q

Are small particles of variable size, up to 1200 nm in diameter, formed in intestinal epithelial cells and transported in blood plasma and lymph

A

Chylomicrons

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10
Q

Hydrolyzed chylomicrons and VLDL at luminal surfaces of blood capillaries by this enzyme which is synthesized by the adipocyte and transferred to capillary cell membrane

A

Lipo-protein lipase

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11
Q

Breaks down triglycerides at the surface of the stored lipid droplets

A

Hormone sensitive lipase

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12
Q

Helps regulate the appetite under normal conditions and participates in regulating the formation of new adipose tissue

A

Leptin

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13
Q

Triglycerides are transported by blood and lymph from the intestine and liver in lipo-protein complexes known as

A

Chylomicrons and VLDL

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14
Q

Chylomicrons and VLDL complexes are partly broken down by __________ releasing free fatty acids and glycerol

A

Lipoprotein lipase

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15
Q

When cyclic AMP is stimulated, this activates ___________ to hydrolyze the stored triglycerides to free fatty acids and glycerol

A

Hormone-sensitive lipase

16
Q

______ was discovered and is well studied in genetically obese mice

A

Leptin

17
Q

In obese humans adipocytes produce adequate or excess quantities of ________ but target cells are not responsive due apparently to insufficient or defective receptors or post receptor signal transduction

A

Leptin

18
Q

Increased ______ adipose tissue raises the risk of diabetes and cardiovascular

A

Visceral

19
Q

Adipose tissue in ______,_________, and __________ resists even long periods of starvation

A

Palms, soles, and retro-orbital fat pads

20
Q

Have the appearance of fibroblasts but accumulate lipid droplets in their cytoplasm

A

Pre adipocytes

21
Q

Pro inflammatory factors released from visceral fat are being investigated for links of ___________ such as diabetes and heart disease

A

Inflammation-related disorders associated with obesity

22
Q

________ is very often associated with age related metabolic changes and may involve reduced activity of the hormone-sensitive lipases of adipocytes causing less fat mobilization out of the cells

A

Adult-onset Obesity

23
Q

Has many small lipid droplets abundant mitochondria, and vasculature all help mediate this tissue principal function of heat production

A

Multilocular

24
Q

In brown fat hormone sensitive lipase doesn’t release fatty acids but are quickly metabolized with a consequent increase in oxygen consumption and heat production

A

Thermogenesis

25
Q

A transmembrane protein that permits the back flow of protons previously transported to the the inter membranous space without passing through the ATP-Synthetase complexes

A

Thermogenin or uncoupling protein ( UCP-1)