Chapter 55: Breast- Male Breast Ca

Question 1

What is the incidence of breast cancer in men?

Answer 1

<1% of all breast cancer cases (1/150)

Question 2

What is the average age at diagnosis?

Answer 2

65 years of age

Question 3

What are the risk factors?

Answer 3

1. Increased estrogen
2. Radiation
3. Gynecomastia from increased estrogen
4. Estrogen therapy
5. Klinefelter’s syndrome (XXY)
6. BRCA2 carriers

Question 4

Is benign gynecomastia a risk factor for male breast cancer?

Answer 4

NO

Question 5

What type of breast cancer do men develop?

Answer 5

Nearly 100% of cases are ductal carcinoma (men do not usually have breast lobules)

Question 6

What are the signs/symptoms of breast cancer in men?

Answer 6

• Breast mass (most are painless)
• breast skin changes (ulcers, retraction)
• and nipple discharge (usually blood or a blood-tinged discharge)

Question 7

What is the most common presentation?

Answer 7

Painless breast mass

Question 8

How is breast cancer in men diagnosed?

Answer 8

Biopsy and mammogram

Question 9

What is the treatment?

Answer 9

1. Mastectomy
2. Sentinel LN dissection of clinically negative axilla
3. Axillary dissection if clinically positive axillary LN