Chapter 5 Flashcards

1
Q

What are the types of lipids

A

Fatty Acids, Triglycerides, Phospholipids, Sterols (fats/oils)

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2
Q

Fatty Acids

A

omega-3 and omega-6 fatty acids, essential for body functions like brain development, immune health, and regulating inflammation.

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3
Q

Triglycerides (TGs)

A

The major form of fat in food and the body

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4
Q

Triglycerides functions

A

providing STORED energy, insulation, and organ protection, lubricates body surface

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5
Q

Phospholipids

A

Lipids attached to phosphate Act as emulsifiers and are amphiphilic

synthesized in body but small part of diet (egg yolks)

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6
Q

Sterols

A

Lipid found in plants and animals

Eating plant sterols helps reduce blood cholesterol

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7
Q

Cholesterol

A

type of sterol found only in animals

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8
Q

Functions of cholesterol

A

Used to make several hormones (estrogen and testosterone) allows cell membrane to remain appropriately fluid at wide range of temp)

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9
Q

AMDR

A

Acceptable Macronutrient Distribution Range

20-35% of total calories should come from fat
including essential fatty acids like linoleic acid(12g women and 17g men) (omega-6) and alpha-linolenic acid (1.1g women and 1.6g men) (omega-3).

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10
Q

Energy Contribution

A

9 kcal/g of fat

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11
Q

Health Issues

A

Elevated intake of trans fats and saturated fats is linked to cardiovascular disease (CVD). On the other hand, monounsaturated and polyunsaturated fats (especially omega-3) reduce CVD risks

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12
Q

Lipoproteins

A

Chylomicrons, VLDLs, LDLs, HDLs

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13
Q

Chylomicrons

A

transport dietary fats from intestine to tissues

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14
Q

VLDLs

A

Very low density proteins: transport lipids (main;y TGs) synthesized in the body to tissues

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15
Q

LDLs

A

transports cholesterol to body (the smaller the more dense)

“Bad Cholesterol” (More TG content = bigger)

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16
Q

HDLs

A

Transport cholesterol from tissues to liver

“Good cholesterol” (high density lipoprotein contains less TGs, smaller)

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17
Q

Cardiovascular Disease (CVD)

A

Dysfunction of heart or blood vessels. The type of fat in our diet can contribute or protect against CVD
The main cause is Atherosclerosis
heart attack or stroke

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18
Q

Artherosclerosis

A

Bodies response to INJURY

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19
Q

increased risk of atherosclerosis and CVD is associated with

A

HIGH LDL cholesterol, with saturated fats increasing LDL and trans fats further elevating risks.
LOW HDL
HIGH TRIGLYCERIDES and VLDL
Conversely, omega-3 fatty acids lower triglycerides and reduce CVD risk.

20
Q

N-6 polyunsaturated FAs

A

Protective against OR may not increase CVD risk

Decreases cholesterol synthesis in liver

21
Q

Dietary sources of N-6

A

oils that are liquid at room temperature
(plant and vegetable oils except palm and coconut oil)

22
Q

N-3 polyunsaturated FAs

A

Protective against CVD risk (FIsh intake most protective DHA and EPA)

  • decreases blood triglycerides
  • decreases formation of blood clots
  • increases HDL-cholesterol
  • helps maintain a normal heart beat
  • Anti-inflammatory properties
23
Q

Saturated fat should…

A

not exceed 10% of energy

24
Q

Polyunsaturated fats (n-6 and n-3 fats) should be….

A

around 10% energy

25
Q

intake of n-3 fatty acids including DHA and EPA should be

A

Emphasized

26
Q

Monounsaturated fats make up…

A

the remainder

27
Q

TRUE or FALSE you should Ingest no trans fats (hydrogenated fat)

A

TRUE

28
Q

Saturated fats increase or reduce cancer…

A

Risk of certain cancers (e.g., breast, colon) due to their role in promoting inflammation and tumor growth.

29
Q

Omega-3 fatty acids reduce or increase cancer risk

A

Reduce cancer risk, particularly for breast and colorectal cancer, thanks to their anti-inflammatory properties.

30
Q

Artificial Trans fats…

A

raise cancer risk

31
Q

naturally occurring trans fats (from animals)

A

may not have the same negative effect for cancer risk

32
Q

Monounsaturated fats

A

neutral or protective effect against cancer, as seen in diets like the Mediterranean diet.

33
Q

CLA

A

(Conjugated Linoleic Acid): Found in beef and dairy,

may help inhibit cancer growth and reduce body fat, but more research is needed.

34
Q

VA

A

Vaccenic Acid: Found in ruminant animal products,
reduces HIGH LDL-C, VLDL-TG and inflammation

35
Q

Fat Substitutes

A

Limit cholesterol, trans fats, and saturated fats

(low fat milk, yogurt and cheese)
(opt for chicken skinless and fish)

36
Q

Alcohol

A

Organic compound (OH- group)
Provides 7 kcal/g
Small intestine has the most Alcohol

37
Q

Alcohol Absorption

A

20% of consumed alcohol is absorbed in stomach
Food slows down the absorption by delaying gastric emptying
Stomach dilutes EtOH

38
Q

Alcohol is mainly metabolized via two pathways

A

ADH (alcohol dehydrogenase) and MEOS (Microsomal Ethanol Oxidizing System)

39
Q

Alcohol Dehydrogenase (ADH)

A

Primarily occurs in the liver, turning alcohol into acetaldehyde.

40
Q

MEOS (Microsomal Ethanol Oxidizing System)

A

Activated during heavy drinking, it produces reactive oxygen species (ROS), contributing to liver damage​

41
Q

Metabolism of EtOH (alcohol)

A
  • Alcohol can cause dehydration
  • Alcohol lost through lungs used
    to estimate blood alcohol
  • Metabolized by the liver
42
Q

How does Alcohol affect Colon

A

toxicity, increased cancer risk, Gut microbiota imbalance, and dehydration, contributing to both short-term discomfort and long-term health risks.

43
Q

Guidelines on alcohol consumption

A

2011:Men are advised to limit consumption to no more than 15 drinks per week, women to 10.
2023: New guidelines suggest reducing intake to 2 drinks per week​

44
Q

Health risks associated with alcohol consumption at different life stages

A

Short-term: Accidents, dehydration, and acute damage to organs like the liver and brain.
Long-term: Chronic use can lead to liver damage including cirrhosis, heart disease, fatty liver, alcoholic hepatitis, hypertension, and increased risk of certain cancers (e.g., breast, colon)​

45
Q

Chronic Alcohol Consumption:

A

Regular, heavy drinking over an extended period. Leads to Obesity, Liver damage, Increased Cancer Risk, Heart disease, Mental health issues, Nutritional Deficiencies

46
Q

Moderate Alcohol Consumption

A

up to 1 drink per day for women and 2 drinks per day for men. may offer some heart health benefits, but even moderate drinking increases cancer risk and may lead to alcohol dependence in the long term​