Chapter 5 Flashcards
Fluid-Mosaic Model
Fluid: phospholipid
Proteins: Mosaic
Model that explains structure and function of cell membrane
Membrane fluidity
cholesterol and carbohydrates (glycoprotein/glycolipid)
Membrane phospholipids
Glycerol, phosphate, fatty acids(2), hydrophobic (non polar, tails) and hydrophilic (polar, head)
amphipathic
on the same molecule
phospholipid head
hydrophilic, head
phospholipid tails
hydrophobic, tails
membrane proteins
proteins on plasma membrane
Integral protein
Penetrate membrane, transmembrane, hydrophobic (alpha helices), hydrophilic channels(beta barrels)
membrane protein
Peripheral
Attached to one layer
outside -> extracellular matrix
inside -> Cytoskeleton
Interact with integrals
membrane protein
Transporters
channels: (doorway into cell)
movement of ion/molecule
may be voltage or ligand gated (open and close)
membrane protein
Carrier: Interact with specific molecules, binds and allows transport, may involve ATP
membrane protein
Channel transporter
doorway into cell
movement of ion/molecule
may be voltage or ligand gated (open and close)
membrane protein
Carrier transporter
Interacts with specific molecules, binds and allows transport, may involve ATP
membrane protein
Enzyme membrane protein
Integral/peripheral
catalyze rxn.s on plasma membrane
membrane protein
Signal transduction (indirect)
receptor protein, specific signal molecule
binding -> confirmation of change
transmit signal and propagate through cell
membrane protein
Cell recognition
Glycoproteins, recognized by plasma membrane, temporary close interaction
membrane protein
Embedded proteins
fully embedded into phospholipid bilayer
Intracellular junctions
Close plasma membrane to plasma membrane connections
protein 1-> protein2
longer lasting communication
tissue formation
Intra/extra cellular protein interactions
connection to extracellular matrix/ cytoskeleton
maintain cell shape and function
stabilize protein location
transmit signal out -> in
Cholesterol
embedded in membrane, membrane fluidity ( we want cholesterol )
“goldilocks”
High temp cholesterol
fluid plasma membrane
Low temp cholesterol
viscous plasma membrane
Carbohydrates
chain/branching outside of cell
bound to glycoproteins/lipids,
cell-cell recognition
Permeability of Plasma membrane
Selectively (semi) permeable