chapter 4: chemistry of behavior Flashcards
Exogenous
Arising from outside the body
Endogenous
Produced inside the body
Presynaptic
Located on the “transmitting” side of a synapse
Synapse
The location at which information flows between a presynaptic neuron and a postsynaptic neuron, often through the conversion of electrical activity in the presynaptic neuron into a secretion of chemical neurotransmitter that alters the functioning of the postsynaptic neuron
Exocytosis
A cellular process that results in the release of a substance into the extracellular space
Neurotransmitter
A signaling chemical, released by a presynaptic neuron, that diffuses across the synaptic cleft to alter the functioning of the postsynaptic neuron
Neurotransmitter receptor
A specialized protein that is embedded in the cell membrane, allowing it to selectively sense and react to molecules of the corresponding neurotransmitter
Postsynaptic
Located on the “receiving” side of a synapse
Reuptake
The reabsorption of molecules of neurotransmitter by the neurons that released them, thereby ending the signaling activity of the transmitter molecules
Transporter
A specialized membrane component that returns transmitter molecules to the presynaptic neuron for reuse
Ionotropic receptor
A receptor protein containing an ion channel that opens when the receptor is bound by an an agonist
Also called ligand-gated ion channel
Metabotropic receptor
A receptor protein that does not contain ion channels but may, when activated, use a G protein system to open nearby ion channels or to produce other cellular effects
Amine neurotransmitter
A neurotransmitter based on modifications of a single amino acid nucleus. Examples include acetylcholine, serotonin, and dopamine
Amino acid neurotransmitter
A neurotransmitter that is itself an amino acid. Examples include GABA, glycine, and glutamate
Peptide neurotransmitter
A neurotransmitter consisting of a short chain of amino acids
Also called neuropeptide
Gas neurotransmitter
A neurotransmitter that is a soluble gas. Examples include nitric oxide and carbon monoxide
Acetylcholine (ACh)
A neurotransmitter found in the autonomic nervous system, motor systems, and throughout the brain
Cholinergic
Referring to cells that use acetylcholine as their synaptic transmitter
Basal forebrain
A region, ventral to the basal ganglia, that is the major source of acetylcholine in the brain
Dopamine (DA)
A monoamine transmitter found in the midbrain –especially the substantial nigra – and in the basal forebrain