chapter 2: cells and structures Flashcards
Neurons
The basic unit of the nervous system, each composed of receptive extensions called dendrites, and integrating cell body, a conducting axon, and a transmitting axon terminal
Also called nerve cells
Glial cells
Nonneuronal brain cells that provide structural, nutritional, and other types of support to the brain
Also called glia
Synapse
The cellular location at which the information is transmitted from a neuron to another cell
Input zone
The part of a neuron that receives information, from other neurons or from specialized sensory structures
Dendrite
An extension of the cell body that receives information from other neurons
Integration zone
The part of a neuron that initiates nerve electrical activity
Cell body or soma
The region of a neuron that is defined by the presence of the cell nucleus
Conduction zone
The part of a neuron over which the nerve’s electrical signal may be actively propagated
Axon
A single extension from the nerve cell that carries action potentials from the cell body toward the axon terminals
Also called nerve fiber
Output zone
The part of a neuron at which the cell sends information to another cell
Axon terminal
The end of an axon or axon collateral, which forms a synapse on a neuron or other target cell
Also called synaptic bouton
Motoneuron
A neuron that transmits neural messages to muscles or glands
Also called motor neuron
Sensory neuron
A nerve cell that is directly affected by changes in the environment, such as light, odor, or touch
Interneuron
A nerve cell that is neither a sensory neuron nor a motoneuron; interneurons receive input from and send output to other neurons
Multipolar neuron
A nerve cell that has many dendrites and a single axon
Bipolar neuron
A nerve cell that has a single dendrite at one end and a single axon at the other end
Unipolar neuron
A nerve cell with a single branch that leaves the cell body and then extends in two directions; one end is the input zone, and the other end is the output zone
Also called monopolar neuron
Presynaptic
Referring to the region of a synapse that releases neurotransmitter
Postsynaptic
Referring to the region of a synapse that receives and responds to neurotransmitter
Presynaptic membrane
The specialized membrane on the axon terminal of a nerve cell that transmits information by releasing neurotransmitter
Postsynaptic membrane
The specialized membrane on the surface of a nerve cell that receives information by responding to neurotransmitter from a presynaptic membrane
Synaptic cleft
The space between the presynaptic and postsynaptic neurons at a synapse
Synaptic vesicle
A small, spherical structure that contains molecules of neurotransmitter
Neurotransmitter
The chemical released from the presynaptic axon terminal that serves as the basis of communication between neurons
Golgi stains
Cell stain that fills the whole cell, useful for identifying type and shape of cells in a region
Nissl stains
Outline all cell bodies, useful for measuring cell body size and density of cells in particular regions
Autoradiography
Cells are manipulated into taking photographs of themselves by staining them with radioactive drugs and placing the brain section on a slide
Immunocytochemistry (ICC)
Brain sections exposed to antibodies that are selective for a protein of interest, then chemicals make the antibodies visible (reveals only the cells that make that protein visible)
In situ hybridization
Uses radioactively labeled lengths of nucleic acid to identify neurons in which a gene of interest has been turned on
Immediate early genes (IEGs)
Expressed when neurons become more active
Researchers use ICC to label the IEG product to identify brain regions that are active during particular behaviors being performed by the animal before death
Horseradish peroxidase (HRP)
Used to identify the cells of origin of a particular set of axons; HRP is taken up into the axon at the terminals and transported back to the cell body
Neurotransmitter receptors
A protein that captures and reacts to molecules of a neurotransmitter or hormone
Also called receptor
Neural plasticity
The ability of the nervous system to change in response to experience or the environment
Also called neuroplasticity
Axon hillock
The cone-shaped area on the cell body from which the axon originates
Innervate
To provide neural input to
Axon collateral
A branch of axon
Axonal transport
The transportation of materials from the neuronal cell body to distant regions in the dendrites and axons, and from the axon terminals back to the cell body
Oligodendrocyte
A type of glial cell that forms myelin in the central nervous system
Schwann cell
A type of glial cell that forms myelin in the peripheral nervous system
Myelin
The fatty insulation around an axon, formed by glial cells. This sheath improves the speed at which nerve impulses are conducted
Node of Ranvier
A gap between successive segments of the myelin sheath where the axon membrane is exposed
Multiple sclerosis
A disorder characterized by the widespread degeneration of myelin
Astrocytes
A star-shaped glial cell with numerous processes (extensions) that run in all directions. Help to modulate neural activity (and blood flow), form synapses, and form the tough outer membranes that swaddle the brain
Microglial cells
Extremely small glial cells that remove cellular debris from injured or dead cells
Also called microglia
Edema
The swelling of tissue, especially in the brain, in response to injury
Gross neuroanatomy
Anatomical features of the nervous system that are apparent to the naked eye
Central nervous system (CNS)
The portion of the nervous system that includes the brain and the spinal cord
Peripheral nervous system
The portion of the nervous system that includes all the nerves and neurons outside the brain and spinal cord
Nerve
A collection of axons bundled together outside of the central nervous system
Motor nerve
A mere that transmits information from the central nervous system to the muscles and glands
Sensory nerve
A nerve that coneys information from the body to the central nervous system
Cranial nerve
A nerve that is connected directly to the brain; there are 12 pairs (one left-sided and one right-sided in each pair)
Spinal nerve
A nerve that emerges from the spinal cord; there are 31 pairs of nerves (one left, one right)
Also called somatic nerve
Autonomic nervous system
The part of the peripheral nervous system that supplies neural connections to glands and to smooth muscles of internal organs
Cervical
Referring to the topmost 8 segments of the spinal cord, in the neck region
Thoracic
Referring to the 12 spinal segments below the cervical (neck) portion of the spinal cord, corresponding to the chest
Lumbar
Referring to the 5 spinal segments that make up the upper part of the lower back