chapter 12: psychopathology Flashcards
delusion
false belief that is strongly held in spite of contrary evidence
schizophrenia
a severe psychopathological disorder characterized by negative symptoms such as emotional withdrawal and impoverished thought, and by positive symptoms such as hallucinations and delusions
positive symptom
in psychiatry, an abnormal behavior state; examples include hallucinations, delusions, and excited motor behavior
negative symptom
in psychiatry, an abnormality that reflects insufficient functioning; examples include emotional and social withdrawal, blunted affect, and slow and impoverished thought and speech
monozygotic
referring to twins derived from a single fertilized egg (identical twins); share an identical set of genes
dizygotic
referring to twins derived from separate eggs (fraternal twins); no more closely genetically related than other full siblings
concordance
a characteristic that is seen in both individuals of a pair of twins
hypofrontality hypothesis
the idea that schizophrenia may reflect underactivation of the frontal lobes
lobotomy
the surgical separation of a portion of the frontal lobes from the rest of the brain, once used as a treatment for schizophrenia and many other ailments
chlorpromazine
an antipsychotic drug that replaced lobotomy as a treatment for schizophrenia; trade name Thorazine
antipsychotic or neuroleptic
any of a class of drugs that alleviate symptoms of schizophrenia, typically by blocking dopamine receptors
dopamine hypothesis
the idea that schizophrenia results from either excessive levels of synaptic dopamine or excessive postsynaptic sensitivity to dopamine
amphetamine psychosis
a delusional and psychotic state, closely resembling acute schizophrenia, that is brought on by repeated use of high doses of amphetamine
dyskinesia
maladaptive motor symptoms that can result from traditional antipsychotic drugs, are permanent
tardive dyskinesia
repetitive, involuntary movements, especially involving the face, mouth, lips, and tongue
super-sensitivity psychosis
marked increase in positive symptoms of schizophrenia after discontinuation or lowered dosage of traditional antipsychotic drugs as a result of dopamine receptor super-sensitivity