Chapter 36 Flashcards

1
Q

signs and symptoms of pulmonary disease
______ and _______ !!!!!!!!!!!!!
pulmonary diseaase is associated with many signs and symptoms, and their specific characteristics often help in identifying the underlying disorder
the most common characteristics are:

A

dyspnea

cough

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2
Q

_________: subjective sensation of uncomfortable breathing

severe
-flaring of the \_\_\_\_\_\_\_\_
-use of accessory \_\_\_\_\_\_\_ of respiration
-retraction of the \_\_\_\_\_\_\_\_\_
on exertion:
shortness of breath with activity

_______: sitting up in a ______ leaning position generally relieves this type of breathing
-supporing the upper body on several _______

A
dyspnea
nostrils
muscles
intercostal spaces
orthopnea
forward
pillows
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3
Q

___________: alveolar ventilation is inadequate in relationship with the metabolic demands

  • leads to __________ from _________ which is high ___ levels
  • is caused by airway _________, _______ restriction, or altered ________ control of breathign
A
hypoventilation
respiratory acidosis
hypercapnea
CO2
obstruction
chest wall
neurologic
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4
Q

__________: alveolar ventilation exceeds the metabolic demands

  • leads to __________ from _______ which is low ___ levels
  • is caused by _______, ________, or severe _________
A
hyperventilation
respiratory alkalosis
hypocapnia
CO2
anxiety, head injury, hypoxemia
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5
Q
the selective bulbous enlargement of the end (\_\_\_\_\_\_\_ segment) of a digit and is commonly associated with diseases that interfere with \_\_\_\_\_\_\_\_\_\_\_
such as:
1
2
3
4
5
A
clubbing
distal
oxygenation
brochiectasis
cystic fibrosis
pulmonary fibrosis
lung abscess
Congenital heart disease
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6
Q

PaO2 - oxygenation of _______
PAO2- the amount of oxygen in the ______

  1. The ____________ is the measure of the difference between the alveolar concentration of ________
    and the arterial concentration of _______. It is used in diagnosing the source of _________
  2. Meausurement helps isolate the location of the problem as either _______(within the ____) or _________(somewhere else in the body
A
arterial blood
alveoli
alveolar-arterial gradient
oxygen
oxgygen
hypoxemia
intrapulmonary, lungs
extrapulmonary
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7
Q

reduced oxygenation of cells in tissues

A

hypoxia

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8
Q

reduced oxygenation of arterial blood (reduced by _______) is caused by ___________

  • diffusion of oxygen through the __________ membrane is impaired if it is _________ or if the _______ available for diffusion is decreased
  • ____________ and __________ cause hypooxemia by the mechanism of abnormal thickness, as occurs with __________(swelling), and pulmonary fibrosis (formation of _________), increases the _____ required for diffusion across the alveolarycapillary membrane so bottom line this causes impairing of the alveolar capillary membrane _______
A
hypoxemia
PaO2
respiratory alternation
alveolocapilarry
thickened 
surface area
pulmonary edema, pulmonary fibrosis
fibrous lesions
time
diffusion
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9
Q

pleural abnormalities
___________
-presence of fluid in the pleural space

_________
-is watery and diffuses out of the _________

________
-is less watery and contains high concentrations of ________ and _______
________: chyle exudate
_______: blood exudate
clinical manifestations: _______ and ______ pain
treatment: ________, _______ and _______

A
pleural effusion
transudative effusion
capillaries
exudative effusion
WBC and plasma proteins
chylothorax
hemothorax 
dyspnea, pleural
thoracentesis
chest tube
surgery
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10
Q

exudative effusion

  • contains high concentrations of WBBCs and may occur in response to an _________ process
  • the presence of a __________ can trigger exudative effusion
  • result of increased ______________
A

inflammatory
malignant cancer
capillary permeability

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11
Q

empyema

  • _______ pleural effusion
  • ______ in the pleural space - causes pulmonary infections (_______,, ________) infected ______

clinical manifestations:
-_____, ____, ______(rapid heart rate), ______, and ________
treatment:
-administration of __________ meds
-drainage of the _________ with a ________
-severe cases: _________ guided pleural drainage, instillation of ________ agents, or ______ injected in the pleural space

A
infected
pus
pneumonia, abscesses
wounds
cyanosis, fever, tachycardia, cough, pleural pain
antimicrobial
pleural space, chest tube
ultrasound
fibrinolytic
DNAse
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12
Q

restrictive lung diseases restrict the lung ________

the lungs are unable to _____ normally diminishing the amount of ___ that can be inspired

A

volume
expand
gas

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13
Q

obstructive lung diseases affect ________
airflowinto and out of the lung is obstructed
increased ________ to air flow caused by _______ of airways

A

gas flow
resistance
narrowing

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14
Q

CXR abnormalities terms
_______ and _______ - air trapping in the alveoli and airways
_________ or _________: consolidation of the lung tissue
__________ or ________: cavities
_______: nodular

A

asthma, emphysema
pneumonia, pulmonary edema
abscesses or TB
lung cancer

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15
Q
a loss of lung volume caused by \_\_\_\_\_\_\_ of alveoli and subsequent \_\_\_\_\_\_ of the part of the lung
etiology
1.  \_\_\_\_\_\_\_\_\_(tumor)
2. \_\_\_\_\_\_\_\_\_ pleural effusion
3
4
5 \_\_\_\_\_\_\_\_\_( within \_\_ hours)
6
A
atelectasis
deflation
collapse
obstructive
nonobstructive
pneumothorax
surfactant deficiency
postoperative, 72
asbestosis
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16
Q
restrictive  lung disorders
atelectasis
\_\_\_\_\_\_\_ of lung tissue
-compression atelctasis
-\_\_\_\_\_\_ compression on the lung
-absorption atelectasis
-gradual \_\_\_\_\_\_\_ of air from obstructed or \_\_\_\_\_\_\_\_\_ alveoli
-\_\_\_\_\_\_ impairement
-decreased production or inactivation of surfactant
clinical manifestations
-\_\_\_\_\_\_, \_\_\_\_\_\_\_, \_\_\_\_\_\_ and \_\_\_\_\_\_\_\_
treatment:
\_\_\_\_\_\_\_\_\_
A
collapse
external
absoprtion
hypoventilated
surfactant
dyspnea, cough, fever, leukocytosis
deep breathing
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17
Q

restrictive lung disorders
__________: excessive amounts of fibrous or connective tissue in lung
_________ pulm fibrosis: no specific cause
-clinical manifestations: increasing ______ on exertion

A

pulmonary fibrosis
idiopathic
dyspnea

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18
Q

restrictive lung disorders
_________
-excess water in the lung from disturbances of ______________ pressure, ________ pressure, or _________
-most common cause: ________ heart disease!!!!!

clinical manifestations: dyspnea, orthopenea, hypoxemia, and increased work of breathing

A
pulmonary edema
capillary hydrostatic
capillary oncotic pressure
capillary permeability
left sided
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19
Q

these are short parallel lines at the lung periphery. these llines represent ___________, which are usually less than 1 cm in length and paraelll to one another at ________ to the pleura

  • they are located _________ in contact w the pleura, but are generally absent along ______ surfaces
  • they may be seen in any zone but are most frequently obserbed at the ______ at the_______ angles on the PA radigraph
A
Kerley B lines
interlobular septa
right angles
peripherally
fissural
lung bases
costophrenic
20
Q

perihilar, interstitial opacities shadow of ________ or _____ appearance. the hatched lines are _______ (kerley lines which represent prominent _________ _____ vessels

A

pulmonary edema
butterfly, bats wings
septal lines
interlobular lymphatic

21
Q
restrictive lung disorders
\_\_\_\_\_\_\_\_ (ALI) or \_\_\_\_\_\_\_\_\_\_\_\_\_ (ARDs)
-is a \_\_\_\_\_\_\_\_ form of respiratory failure characterized by acute \_\_\_\_\_\_\_\_\_\_\_\_\_ and \_\_\_\_\_\_\_\_\_\_\_ injury
-injury to the pulmonary capillary \_\_\_\_\_\_\_\_\_\_\_
-\_\_\_\_\_\_\_\_\_ capillary permeability
-\_\_\_\_\_\_\_\_\_\_
-\_\_\_\_\_\_\_\_\_\_\_\_ inactivation
-\_\_\_\_\_\_\_ and \_\_\_\_\_\_\_\_\_
A
acute lung injury
acute respiratory distress syndrome
fulminant
lung inflammation
diffuse alveocapillary
increased
inflammation
surfactant
edema, atelectasis
22
Q

ARDS pathophys

  • alveoli and respiratory bronchioles fill with fluid as a result of __________ of surfactant and the impairment of _______ ______ cells
  • ________ release inflammatory mediators such as ____________, ___________, ________, __________ and _______ activating factor
A
inactivation
type 2 alveolar 
neutrophils
proteolytic enzymes
oxygen-free radicals
prostaglandins
leukotrienes
platelet
23
Q
obstructive pulmonary disease
1
2
3
4 \_\_\_\_\_\_\_\_ plus \_\_\_\_\_\_\_\_\_ equals \_\_\_\_\_\_\_\_\_\_\_
A
asthma
chronic bronchitis
emphysema
chronic bronchitis
emphysema
chronic obstructive pulmonary disorder (COPD)
24
Q

obstructive pulmonary disease
air obstruction is worse with expiration
disease requires more ______ to expire a volume of air

A

force

25
Q

_______
episodic attacks of bronchospasm, bronchial inflammation, mucosal edema, and increased mucous production
early asthmatic response
-_____, may contribute to the pathophysiologic characteristics of asthma
-inflammatory mediators produced by asthma:
1
2
3
4

the release of toxic _________ contributes to increased ________ ___________

clinical manifestations:
inspiratory and expiratory ________, ______, ________ cough and _________

A
asthma
IgE
histamine
bradykinin
leukotrienes
prostaglandins
neuropeptides
bronchial hyperresponsiveness
wheezing
dyspnea
nonproductive
tachypnea
26
Q

chronic bronchitis
_______ - _______ is more severe
hypersecretion of ____ and chronic productive cough that lasts at least __ months of the year and for at least __ consecutive years
pathophysiology
the production of mucus associated w this is due to increased in _________ size
-inspired irritants increase ______ production, size and number of mucous glands and bronchial ______; mucus is _____ than normal
-________ bronchial smooth muscle
-______ and _______
-airways ______ early in expiration, ______ gas in the lung

A
blue bloaters 
hypoxia
mucus
3
2
goblet cell
mucus
edema
thicker
hypertrophied
hypoxemia, hypercapnia
collapse
trapping
27
Q
chronic bronchitis
clinical manifestations:
- decreased \_\_\_\_\_\_\_ tolerance
-\_\_\_\_\_\_\_\_ and \_\_\_\_
-productive \_\_\_\_\_\_ "smokers cough"
becomes \_\_\_\_\_\_\_\_\_\_

treatment: _______ cessation: disease can be halted

A
exercise
wheezing, SOB
cough
copious
smoking
28
Q

emphysema
______, ________ breathing, _____ chest
-abnormal permanent enlargement of the __________ airways accompanied by the destruction of the ________ walls without obvious ________
-loss of _________
-primary emphysema
-_________ deficiency of the enzyme __________
-secondary emphysema
-_________: main cause
-________, occupational ______ and _______ respiratory infections, possible contributers

A
pink puffer
pursed
barrel
gas-exchange
alveolar
fibrosis
elastic recoil
inherited 
a1-antitrypsin
cigarette smoke
air pollution
exposures
childhood
29
Q

emphysema
clinical manifestations
include unexplained ________, ______ on exertion, use of _______ muscles, and ______ with prolonged ________

A
weight loss
dyspnea
accessory
tachypnea
expiration
30
Q

emphysema
_______ inflamed lungs mean that is filled with more air than usual. this is a common finding in someone with _____. The hyperinflation also causes the ____________ _______

lateral chest xray
the _____ of the diaphragm are significantly ______. the thorax can be described as ___________

A
hyperinflamed
COPD
flattened diaphragm
domes
flattened
barrel chest
31
Q
emphysema
treatment
the initial step in the management of emphysema: \_\_\_\_\_\_\_\_\_\_
pulmonary \_\_\_\_\_
improved \_\_\_\_\_\_
\_\_\_\_\_\_ techniques
A

smoking cessation
rehab
nutrition
breathing

32
Q

pneumonia
infection of the _______ respiratory tract
responsible for more disease and death than any other infection

A

lower

33
Q

community acquired pneumonia (CAP)
one of the most common reasons for hospitilization in the USA

1
2
3

A

streptococcus pneumoniae
H. influenza
Moraxella Catarrhalis

34
Q
Ventilatory associated pneumonia (VAP)
develops after 48 hours on a ventilator
1
2
3
A
pseudomonas
staphylococcus aureus (MRSA)
klebsiella
35
Q

heath care associated pneumonia (HCAP)
recent hospitilization residence in a nursing home
extended care facility, home infusions therapy

1
2
3

A
pseudomonas
staphylococcus aureus (MRSA)
klebsiella
36
Q

hospital acquired pneumonia
most common nosocomial infection. has the greatest _______
develops after 48 hours of being inpatient

1
2
3

A
pseudomonas
staphylococcus aureus (MRSA)
klebsiella
37
Q

pneumonia
routes of infection
___________

most common route of _______ respiratory tract infection is via _________ of _______ secretions

A

aspiration
lower
aspiration
oropharyngeal

38
Q

streptococcus pneumoniae

\_\_\_\_\_\_\_\_ pneumonia
-\_\_\_, resulting in inflammatory \_\_\_\_\_ and cells, causes \_\_\_\_\_\_ edema
-edema creates a medium for the multiplication of \_\_\_\_\_\_\_ and aids in the spread of infection into \_\_\_\_\_\_ portions of the lung
-involved lobe undergoes \_\_\_\_\_\_\_\_\_\_
four phases:
1
2
3
4
A
pneumococcal
ALI
cytokines
alveolar
bacteria
adjacent
consolidation
consolidation
red hepatization
gray hepitazation
resolution
39
Q

pneumonia
_______ pneumonia
-is seasonal; usually mild and self limiting
-can set the stage for a ______ bacterial infeciton
-provides an ideal environment for bacterial growth and by damaging _______ epithelial cells, which normally prevents _____ from reaching the airways
most common form: ________

clinical manifestations: for ___________ look for rapid onset of ______ _____ preceded by an ______ respiratory infection, followed by ______, ______ chest pain, productive ______ (_____-_____ or _____)

A
viral
secondary
ciliated 
pathogens
influenza
streptococcus pneumoniae
shaking chills
upper 
fever
pleuritic
cough
yellowish-green
rust
40
Q

pneumonia
treatment
bacterial pneumonia: _______
viral pneumonia: supportive ________ ______, unless ________ bacterial infection is present

A

antibiotics
therapy alone
secondary

41
Q

tuberculosis
a bacterial infection caused by mycobacterium tubercolisis typically affects the lungs

pathophys
airborne droplet transmission
tubercle formation: granulomatous lesion
caseous necrosis:cheese like material
may remain dormant for life or cause active disease
isolation of ________ by enclosing them in _______ and surrounding them with _________

A

bacilli
tubercles
scar tissue

42
Q

tuberculosis
how the body walls off the bacilli
in TB, the body walls off the bacilli in a tubercle by stimulating ______ __________ ______ that activate _________

in defense, ________ and _________ release _______, which inhibits the replication of the microorganism and stimulates more ______ to attack the bacterium.

A
apoptotic infected macrophages
cytotoxic T cells
macrophages, lymphocytes
interferon
macrophages
43
Q

tuberculosis
(picture in slide)
a patchy ____ infiltrate can be seen in upper _______

A

dense

left lobe

44
Q

acute bronchitis
is an acute infection or inflammation of airways or bronchi
commonly follows a _______ illness
-causes symptoms similar to _________ but does not demonstrate pulmonary ________ and chest ________
-clinical manifestations: ________ cough occurs in _______ and is aggravated by ____, _____ or dusty air
-treatmentL rest, _______, _______ and __________ (_____)

A
viral
pneumonia
consolidation
infiltrates
nonproductive
paroxysms
cold, dry
aspirin, humidity, cough suppressant
codeine
45
Q

pulmonary emblolus that impairs blood flow to a segment of the lung results in an area where ______ are ventilated but not ______, which causes ____________

A

alveoli
perfused
alveolar dead space

46
Q

aging and the pulmonary system
loss of _______
________ of the chest wall

A

recoil

stiffening