Chapter 18 Flashcards
meningitis
clinical manifestations
_________, ________
kernig sign
brudzinski sign
multiple sclerosis
______ and _______ of the central nervous system.
Various mechanisms cause irreversible tissue damage of the CNS (inflammation, _______ injury, demyelination, scarring or _____ formation, and ____ degeneration) that characterizes multiple sclerosis
MS is described as occurring when a ____ infectious insult to the CNS has occurred in a ______ susceptible individual with a subsequent abnormal immune response in the CNS
demyelination, inflammation oligodendrocyte plaque axonal previous genetically
classic cerebral concussion Grade IV Physiologic and neurologic dysfunction without substantial anatomic disruption Loss of \_\_\_\_\_\_\_\_ (<6 hours) \_\_\_\_\_\_ and \_\_\_\_\_\_ amnesia Uncomplicated (no focal injury) Complicated (focal injury)
consciousness
anterograde
retrograde
Clinical manifestationsimmediately noted after a spinal cord injury
A complete loss of ____ function in all segments ____ the level of the lesion characterizes a spinal cord injury. Severe impairment below the level of the lesion is obvious; it includes ____ and _____ in muscles, absence of _____, loss of ____ and rectal control, transient ___in blood pressure, and poor _____circulation.
reflex below paralysis flaccidity sensation bladder drop venous
abscess
Abscesses may occur in association with a contiguous spread of infection, such as the ______, _____cells, ____ cavity, and nasal _____
middle ear
mastoid
nasal
sinuses
demyelinating disorders
types
CNS: _______ is an autoimmune disorder diffusely involving the degeneration of CNS myelin and loss of axons
multiple sclerosis
tick borne spirochete bacterial infection
lyme disease
neuromuscular junction disorders
myasthenia gravis
Chronic ____ disease
__ antibody produced against _______ receptors on the postsynaptic membrane
autoimmune
IgG
acetylcholine
mild concussion
mild but traumatic brain injury
immediate but transitory effects
Temporary _____ disturbances, causing _____ and ______ deficits but no loss of consciousness in grades I and II
Grade I—_______, ________, and momentary _____, resolving within __ minutes
Grade II—Momentary _____ and retrograde _____
Grade III—Confusion with retrograde and ______amnesia upon and after impact; loss of consciousness for seconds or minutes
axonal attention memory confusion, disorientation, amnesia 15 confusion amnesia anterograde
faulty control of sweating
A spinal cord injury results in disturbed thermal control because the ______ is unable to regulate a damaged _______ nervous system.
This damage causes faulty control of _____ and ______ through capillary dilation.
hypothalamus
sympathetic
sweating
radiation
Diffuse Axonal Injuries DAIs
Focal brain injuries account for more than ____s of head injury deaths; DAIs accounts for less than _____
However, more severely disabled survivors, including those in an _______ state or reduced level of consciousness, have DAIs.
2/3
1/3
unresponsive
encephalitis
most common form: caused by ___________ (mosquito borne) and ________ virus
arthropodborne
herpes simplex
___-___motor and sensory changes of the lateral ____ legs and __ of the feet
Clinical manifestations of posterolateral protrusions include radicular pain exacerbated by movement and straining (medial calf suggests __; lateral calf suggests ___ root compression).
L5-S1
legs, soles
L5
S1
neurologic complications of AIDs
Opportunistic infections- Opportunistic infections may be bacterial, fungal, protozoal, or viral in origin and produce nervous system disease. ____________s an example of such an infection.
Parasitic infection
__________: Most common
cryptococcus neoformans
toxoplasmosis
cerebrovacular accident
greatest risk factor
hypertension