Chapter 32 Flashcards

1
Q

What 3 things does the thyroid secrete

A

Thyroxine T3
Tri-ildothyronine T4
Calcitonin

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2
Q

What part of the body mobilizes calcium from the bones so it can be used by the body

A

Parathyroid

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3
Q

How does the parathyroid gland play a role in cardiovascular, neuromuscular, and endocrine systems

A

Calcium is a big part of the action potential of cells

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4
Q

What is a function of the thyroid gland

A

Regulates protein, lipids, and carb metabolism (weight)

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5
Q

What is a function of the thyroid

A

Normal growth and development

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6
Q

What is a function of the thyroid

A

Thermoregulation (hot and cold)

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7
Q

What does it mean if you have hypothyroidism

A

Deficiency in thyroid hormones

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8
Q

What is primary hypothyroidism

A

Abnormality in the thyroid gland itself

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9
Q

What is secondary hypothyroidism

A

Pituitary gland is dysfunctional, does not secret thyroid stimulating hormone

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10
Q

What is tertiary hypothyroidism

A

When the hypothalamus does not secret thyrotropin releasing hormone needed to maintain TSH and thyroid hormone levels

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11
Q

Congenital hypothyroidism happens in which population

A

Children

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12
Q

Is primary, secondary or tertiary hypothyroidism the most common

A

Primary

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13
Q

In what population does myxedema occur (hypothyroidism)

A

Adults

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14
Q

What is a goiter (hypothyroidism)

A

Enlargement of thyroid gland, caused by over stimulation of TSH on thyroid, TSH is elevated because there is no thyroid hormone in circulation

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15
Q

Certain drugs with high amounts of iodine can cause hypothyroidism. What is a common drug

A

Amiodarone

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16
Q

Symptoms of Hypothyroidism

A

Cold intolerance
Weight gain
Depression
Dry brittle hair and nails
Fatigue

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17
Q

What does euthyroid mean

A

Normal thyroid levels

18
Q

What is the mechanism of action for thyroid replacement drugs

A

Replace what the thyroid cannot produce

19
Q

What foods should patients avoid when taking thyroid replacement drugs

A

Soy beans
Calcium
Walnuts
Fiber

20
Q

Can thyroid replacement drugs help treat goiters?

A

Yes

21
Q

T/F thyroid replacement drugs are often needed when the thyroid has been removed or destroyed by iodine

A

True

22
Q

Can thyroid replacement drugs be used during pregnancy

A

Yes

23
Q

When is thyroid replacement drugs contraindicated

A

MI
Adrenal insufficiency
Hyperthyroidism

24
Q

Adverse effects of thyroid replacement drugs

A

Cardiac dysrhythmias
Hyperthyroidism and all it’s symptoms

25
Q

Levothyroxine interacts with warfarin in what way

A

Enhances warfarin so lower the dose of warfarin when taking this

26
Q

Levothyroxine interacts with digoxin and insulin in what way

A

Reduces efficacy, increase dose of insulin and digoxin

27
Q

Levothyroxine interacts with epinephrine in what way

A

Makes the person more sensitive to epinephrine

28
Q

Can you take Levothyroxine at the same time as multivitamins or antacids

A

No. They reduce absorption of Levothyroxine in the GI tract

29
Q

Can you discontinue Levothyroxine instantly

A

No

30
Q

Can you take Levothyroxine at any time of day

A

Take at the same time each day to maintain levels. Take in morning to reduce insomnia

31
Q

What unit is Levothyroxine dosed in

A

mcg

32
Q

Can you switch brands of Levothyroxine

A

No. They are not equivalent to each other. NEVER CHANGE BRANDS

33
Q

What is Hyperthyroidism

A

Excessive thyroid hormones

34
Q

Is hyperthyroidism or hypothyroidism more common

A

Hypothyroidism

35
Q

What diseases can cause Hyperthyroidism

A

Graves’ disease
Multi nodular
Plummers disease
Thyroid storm (stress/infection)

36
Q

Symptoms of Hyperthyroidism

A

Diarrhea
Flushing
Increased appetite
Muscle weakness
Sleep disorders
Altered menstrual flow
Fatigue (insomnia)
Palpitations
Nervousness
Heat intolerance
Irritability
Bulging eyes

37
Q

What thyroid drugs cause liver and bone marrow toxicity

A

Anti-thyroid drugs

38
Q

What are 2 ways to treat hyperthyroidism

A

Removal of thyroid
Iodine destroys gland

39
Q

Should you take antithyroid drugs on an empty stomach or with food

A

With food

40
Q

What foods should be avoided with antithyroid drugs

A

Tofu, shell fish, turnips, iron, magnesium, iodized salt, aluminum

41
Q

Should you take thyroid replacement drugs with food or on an empty stomach

A

60 mins before food

42
Q

What is an adverse effect of antithyroid drugs that needs to be monitored

A

Leukopenia