Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

251 Final > Chapter 28 > Flashcards

Chapter 28 Flashcards

1
Q

What are the two main forms of lipids in the blood

A

Triglycerides
Cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What makes a lipoprotein

A

Triglyceride/Cholesterol with apolipoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Is low density lipoprotein or high density lipoprotein better for the body

A

HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where does lipid metabolism occur

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the Framingham risk score

A

Ratio of HDL to LDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the 4 types of antilipemics

A

HMG-CoA reductase inhibitors (statins)
Bile acid sequestrants
B vitamin niacin
Fibric acid derivative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of medication is not an antilipemic but is used to achieve the same goal

A

Cholesterol absorption inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the goal of antilipemics

A

Decrease LDL, increase HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What antilipemic is the first line therapy for hyper cholesterolemia

A

Statins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What do statins do

A

Decrease blood cholesterol levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is an adverse effect of statins

A

Rhabdomyolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is Rhabdomyolysis

A

Breakdown of muscle protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why are statins usually taken at night

A

Cholesterol is mainly produced by the body when it is asleep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What do bile acid sequestrants do

A

Prevent reabsorption of bile acids in small intestine. Bile acid needed to absorb cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What drug is commonly used as an adjuvant with statins

A

Bile acid sequestrants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

High doses of which antilipemic drug decrease the absorption of fat soluble vitamins A D E K

A

Bile acid sequestrants

17
Q

What do niacins do

A

Reduce metabolism of cholesterol and triglycerides, LDL decrease, HDL increase

18
Q

Niacin taken with which other antilipemic drug increases risk for myopathy

A

Statins

19
Q

What do fibric acid derivatives do

A

Activate lipoprotein lipase to break down cholesterol

20
Q

Gemifibrozil enhances the action of which drug

A

Anticoagulants

21
Q

What do cholesterol absorption inhibitors do

A

Inhibit absorption of cholesterol from small intestine

22
Q

Can cholesterol absorption inhibitors be used with fibric acid derivatives

A

251 Final (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions