Chapter 3 Lecture 5 - Membrane Transport Flashcards
Compartmentation
Separation allows specialization
Functional Classes of Membrane Proteins (6)
- Receptor
- Enzyme
- Channel
- Cell identity marker
- Cell Adhesion Molecule
- Carrier
How does carrier mediated transport work
Molecule binds from one side, shape changes to close the side from which the molecule entered, other side is opened, solute is released
Saturation (in terms of carrier mediated transport)
max number of molecules bound to carriers, no matter how many are waiting, rate remains the same
Uniport transporters
Simplest, transport 1 type in 1 direction
Coupled transporters
2 solutes
Symport
Type of coupled transporter, 2 solutes in the same direction
Antiport
2 solutes in opposite directions
Facilitated diffusion
Passive transport, solute moves down concentration gradient
Steps to facilitated diffusion
- Solute binds to 1 side
- Conformation changes
- Solute released on other side
Primary Active Transport
ATP-powered carrier mediated transport, solute moves up concentration gradient
What does primary active transport contribute to (in terms of equilibrium)
Disequilibrium
Example of primary active transport
Sodium potassium pump
Secondary Active Transport
Requires ATP indirectly, coupled transporters used
Steps to secondary active transport
- one molecule moves down concentration gradient
2. Step 1 powers second molecule to move up concentration gradient