Chapter 3: Concepts Of Cellular Function Flashcards
List the 9 Cell Shapes
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Squamous Stellate Spheroidal Cuboidal Columnar Polygonal Discoid Fusiform Fibrous
Squamous
Thin, flat and bulge in the center
Fried Egg
Cuboidal
Square, equal height and width
Columnar
Taller than wide
Polygonal
Irregular angular shape, multiple sides
Stellate
Multiple pointed processes
Star like shape
Spheroidal
Round to oval
Discoid
Disc shaped
Red blood cells
Fusiform
Spindle shaped, thick middle, tapered ends
Fibrous
Long, slender, threadlike
(IFC) Cytoplasm
Contains?
Fluid between the nucleus and plasma membrane
Contains organelles and cytoskeleton
(EFC) Extracellular Fluid
Fluid outside of the cell
Plasma Membrane
Made of?
Composition and Function?
Surrounds cell and defines boundaries
Governs interactions
Controls the passage
Made of proteins and lipids
Composition and function can vary from one region of the cell to another
Unit Membrane
Forms the border of the cell or any of its organelles
Looks like a pair of dark parallel lines around the cell
3 Membrane Lipids
Phospholipids
Cholesterol
Glycolipids
Phospholipids
- Amphiphilic molecules arranged in a bilayer
- Hydrophilic heads face water on Membrane
- Hydrophobic tail directed towards the center, avoiding water
- Drift laterally
- Movement keeps Membrane fluid
Cholesterol
20% of Membrane Lipids
Holds phospholipids still and can stiffen Membrane
Glycolipids
5% of the Membrane Lipids
Phospholipids with short carbohydrates chains on extracellular face
Contributes to GLYCOCALYX
Intracellular Face
Faces cytoplasm
Extracellular face
Faces outwards
Integral Protein
Penetrates the phospholipid bilayer
Peripheral Protein
Adhere to one face of the Membrane
Usually tethered to the cytoplasm
Transmembrane Protein
Integral proteins-pass through the cell
Hydrophilic regions in contact with cytoplasm and Extracellular fluids
Hydrophobic regions that pass through lipid of Membrane
Most are glycoproteins
Drift freely in phospholipids or anchor to cytoskeleton
6 Proteins by Function
REIGCC
Receptor Enzyme Ion Channel Gated Ion Channel Cell-Identity Marker Cell-Adhesion
Receptor
binds to chemical messengers from other cells
- hormones
- neurotransmitters
Communication via chemical signals
Enzyme
Breakdown chemical messages and terminate their effects
Ion Channel
Channel of protein that is constantly open and allows ions to pass into and out of the cell
Gated Ion Channel
A gated channel that opens and closes to allow ions through only at certain times
Cell-Identity Marker
Glycoprotein acting as a cell-identity marker distinguishing the body’s own cells from foreign invaders cells
Cell-Adhesion
Molecule(CAM) binds cells to each other and Extracellular material
Cells do not survive unless linked to Extracellular material
Glycocalyx
Unique fuzzy coat external to plasma membrane
- animal cells
- Carbs- glycolipids, glycoproteins
- Identity tags
7 Functions of Glycocalyx
PDF ICET
Protection (cushion plasma membrane)
Defense Against Cancer (immune defense)
Fertilization (allows sperm to identify egg)
Immunity to infection (recognition of health cells)
Cell Adhesion
Embryonic Development (guide embryonic cells)
Transplant Compatibility
Microvilli
Extension of the Membrane
- Increase cells surface
- 15-40 times more absorption
Can be dense and spear as fringe
Tugged and”milked” from protein in the cytoplasm
Non-Motile Cilla
Hair- like about 7-10 um long
Every human cell has at least one
Serve sensory functions monitoring nearby conditions
Motile Cilia
Less widespread
* respiratory track, uterine tubes, cavities of brain and testes
50-200 on a cell
Beat in waves-same direction- to propel materials
Beat in saline layer below mucus
Flagella
Tail of sperm- only functional flagellum
Whip-like structure with structure identical to cilium
* much longer than cilium
Movement is snakelike
Active Transport
Consume ATP
include active and vesicular transports
Passive Transport
Requires no energy(ATP) from the cell
Random molecular motion of particles
ex: filtration, diffusion, osmosis
Filtration
Passive or Active?
Carrier?
Physical pressure forces fluid through a selectively permeable membrane
Passive
ex: Coffee filter
Biological ex: filtration of waste from the blood in the kidneys while holding back blood cells and proteins
Diffusion
Passive or Active?
Carrier?
Net movement of particles from a place of high concentration to a place of low concentration- result of constant spontaneous motion
Passive
Osmosis
Passive or Active?
Carrier?
Net flow of water from one side(high concentration)
of a selectively permeable membrane to the other side (low concentration)
Passive
Carrier-Mediated Transport
Carrier binds to solutes that transport them to the other side of the membrane
* Can occur in and our of cell or organelle
Facilitated Diffusion
Passive or Active?
Carrier?
Carrier-mediated transport of a solute through a membrane down its concentration gradient
No ATP required= Passive
Primary Active Transport
Passive or Active?
Carrier?
carrier moves a substance through a cell membrane up its concentration gradient
Uses ATP= Active
Secondary Active Transport
Passive or Active?
Carrier?
Same as active but only depends indirectly on ATP
* hitches a ride on already active systems
Vesicular Transport
Passive or Active?
Carrier?
Two types?
Movement of large particles , droplets of water or numerous molecules through the membrane via bubble like vesicles
Active
- endocytosis
- exocytosis
Exocytosis
Passive or Active?
Carrier?
Process of discharging material from a cell
used to replace membrane
5 factors affecting diffusion
TSMMM
Temperature Steepness of Concentration Gradient Molecular weight Membrane Surface Area Membrane Permeability
Tonicity
3 types?
ability of a solution to affect the fluid volume and pressure in the cell
* depends on concentration and permeability of solute
3 types
- Hypotonic
- Hypertonic
- Isotonic
Hypotonic
Effect on the cell?
Solution has lower concentration of non-permeating solutes then the ICF
Effect: causes cell to absorb water and swell
Hypertonic
Effect on the cell?
Solution has a higher concentration of non- permeating solutes than the ICF
Effect: Causes cells to lose water and shrink
Isotonic
Effect on the cell?
Equal concentrating of non- permeating solutes
Effect: Causes no change in cells (ex: normal saline)
3 Types of Carriers
USA
Uniports
Symports
Antiports
Uniports
Carry only one type of solute
Symports
Carry two or more solutes through the membrane at the same time in the same direction
Antiports
Carry two or more solutes through the membrane at the same time in DIFFERENT directions
4 Functions of Sodium- Potassium Pump
MSHR
Maintenance of Membrane Potential
Secondary Active Transport
Heat Production
Regulation of Cell Volume
2 Types of Vesicular Transport
Endocytosis
Exocytosis
Endocytosis
Bringing materials into the cell
Exocytosis
Bringing materials out of the cell
Cytoskeleton
Determines?
Composed of?
structure and support the cell
Determine shape, organization,direction of material movement, and cell movement
Composed of: microfilaments, intermediate fibers, and microtubules
Microfilaments
6nm thick made of protein actin
Form terminal web
supportive cores of microvilli
Intermediate Fibers
8-10 nm thick
Give cell shape, resists stress, junctions with other cells
Microtubules
- 25 nm thick
- Radiate from centrosome, hold organelles in place, maintain cell shape, “Rail Road Tracks”
- Form Cilia and flagella base
- Beating movement
- NOT permanent (created and destroyed as needed)
6 Membranous Organelles
MLGPEN
Mitochondria Lysosomes Golgi Complex Peroxisomes Endoplasmic Reticulum Nucleus
4 Non-Membranous Organelles
CCRB
Centrioles
Centrosomes
Ribosomes
Basal Bodies
Nucleus
- Largest organelle
- 1 per cell
- Contains cell chromosomes
- genetic CONTROL CENTER
- Enclosed by nuclear envelope
Endoplasmic Reticulum (ER)
Functions: FDCM
Types?
- Interconnected Channels- CISTERNAE
Functions:
- Synthesizes proteins and steroids
- Detoxifies alcohol and drugs
- Manufactures all membranes of the cell
- Calcium storage
Smooth and Rough
Ribosomes
Function?
Small granules of protein and RNA found in the nucleus, cytosol, and on the rough ER
Function: read coded genetic messages and assemble amino acids into proteins
Golgi Complex
Functions?
Small system of flattened and curved cisternae
*stack of pita bread
Functions:
- Synthesizes carbohydrates
- Puts finishing touches on proteins
Lysosomes
Functions?
Package of enzymes bound by unit membrane
- Round or oval
- produced by golgi complex
Functions:
- Hydrolyze substances
- Digest and dispose of organelles
- Aide in cell suicide(autolysis)
Peroxisomes
Functions?
Resemble Lysosome- different enzymes
Produced my rough ER
Abundant in kidney and liver
Functions:
*Use molecular oxygen to oxidize organic molecules
Mitochondria
Function?
Power house of the cell
lot of inter folds- maze like- ovoid shape
Function: synthesizes ATP
Centrioles
Function?
cylinder assembly of microtubules
ALWAYS 2 lying perpendicular- forms centrosome
Base of cilia and flagellum
Function: role in cell division
Inclusions
2 types?
Never enclose in a unit membrane
Not essential for cell survival
Types:
- Stored Cellular Products
- Foreign Bodies
Stored Cellular Products
Glycogen granules, pigments, and fat droplets
Foreign Bodies
viruses, intercellular bacteria, dust particles