Chapter 3: Both Inflammations Flashcards
According to what factors is Inflammation classified into? (2 points)
Lesion duration
Histologic appearances
What are the 3 types of Inflammation?
Acute
Chronic
Subacute
Define subacute inflammation
Categorized between acute and chronic Inflammation types
Which 2 types of Inflammation are the histologic appearances?
Acute
Chronic
What are the Systemic effects/manifestations of Inflammation? (8 points)
Fever
Weight loss
4 Responses
Leukocytosis
Or
Leukopenia
What are these 4 responses?
Endocrinal
Behavioral
Metabolic
Autonomic
What is the most important systemic effect/ manifestation of Inflammation?
Fever
What coordinate the Fever? (2 points)
Hypothalamus
Cytokines
What coordinates the Hypothalamus?
Cytokines
What are the types of Cytokines that coordinate the Fever?
IL-1
IL-6
TNF-α
Which cells release the Cytokines?
Macrophages
Others
What do the Endocranial and Metabolic responses include? (6 points)
4 Proteins
Glucocorticoids
Vasopressin
What are the 4 proteins included in the Endocranial and Metabolic responses?
C-reactive
Serum Amyloid A
Complement
Coagulation
What are these proteins secreted from?
Liver
Describe the secretion of Glucocorticoids
Increased
Describe the secretion of Vasopressin
Decreased
What do the Autonomic responses include?
4 points
Blood flow redirection
Pulse rate
Blood pressure
Sweating
What is the blood flow directed from?
Cutaneous
What is the blood flow directed to?
Deep Vascular bed
Describe the pulse rate
Increased
Describe the blood pressure
Increased
Describe the sweating
Decreased
What do the Behavioral responses include?
4 points
Rigor
Chills
Anorexia
Malaise
What is a common feature of Inflammation?
Leukocytosis
What are the examples that cause Leukocytosis? (4 points)
2 Infections
Parasitic infestations
Allergic reactions
What are the 2 examples of infections that cause Leukocytosis?
Bacterial
Some Viral
Among all the causes, which cause is Leukocytosis especially common in?
Bacterial Infection
Which cells do most Bacterial infections induce?
Neutrophils
What are examples of some Viral infections that cause Leukocytosis? (2 points)
Infectious Mononucleosis
Mumps
What are examples of Parasitic infestations and Allergic reactions that cause Leukocytosis? (2 points)
Bronchial Asthma
Hay Fever
Which cells are induced by Parasitic infestations?
Eosinophilia
What unit is used to count the Leukocytosis?
cells/mm3
What is the Leukocytosis usual range number?
15K-20K
What is Leukopenia a feature of?
Typhoid Fever
Some Parasitic Infections
The action of what causes Weight loss? (2 points)
IL-1
TNF-α
What is the action of IL-1 and TNF-α?
Increase Catabolism
What do IL-1 and TNF-α increase the Catabolism of? (3 points)
Muscles
Tissue
Liver
Which muscles’ catabolism increases by IL-1 and TNF-α?
Skeletal
Which tissue’s catabolism increases by IL-1 and TNF-α?
Adipose
What does the increased Catabolism of these examples cause?
Negative Nitrogen Balance