Chapter 3: Both Inflammations Flashcards

1
Q

According to what factors is Inflammation classified into? (2 points)

A

Lesion duration

Histologic appearances

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2
Q

What are the 3 types of Inflammation?

A

Acute
Chronic
Subacute

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3
Q

Define subacute inflammation

A

Categorized between acute and chronic Inflammation types

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4
Q

Which 2 types of Inflammation are the histologic appearances?

A

Acute

Chronic

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5
Q

What are the Systemic effects/manifestations of Inflammation? (8 points)

A

Fever
Weight loss
4 Responses

Leukocytosis
Or
Leukopenia

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6
Q

What are these 4 responses?

A

Endocrinal
Behavioral
Metabolic
Autonomic

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7
Q

What is the most important systemic effect/ manifestation of Inflammation?

A

Fever

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8
Q

What coordinate the Fever? (2 points)

A

Hypothalamus

Cytokines

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9
Q

What coordinates the Hypothalamus?

A

Cytokines

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10
Q

What are the types of Cytokines that coordinate the Fever?

A

IL-1
IL-6
TNF-α

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11
Q

Which cells release the Cytokines?

A

Macrophages

Others

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12
Q

What do the Endocranial and Metabolic responses include? (6 points)

A

4 Proteins
Glucocorticoids
Vasopressin

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13
Q

What are the 4 proteins included in the Endocranial and Metabolic responses?

A

C-reactive
Serum Amyloid A
Complement
Coagulation

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14
Q

What are these proteins secreted from?

A

Liver

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15
Q

Describe the secretion of Glucocorticoids

A

Increased

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16
Q

Describe the secretion of Vasopressin

A

Decreased

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17
Q

What do the Autonomic responses include?

4 points

A

Blood flow redirection
Pulse rate
Blood pressure
Sweating

18
Q

What is the blood flow directed from?

A

Cutaneous

19
Q

What is the blood flow directed to?

A

Deep Vascular bed

20
Q

Describe the pulse rate

A

Increased

21
Q

Describe the blood pressure

A

Increased

22
Q

Describe the sweating

A

Decreased

23
Q

What do the Behavioral responses include?

4 points

A

Rigor
Chills
Anorexia
Malaise

24
Q

What is a common feature of Inflammation?

A

Leukocytosis

25
Q

What are the examples that cause Leukocytosis? (4 points)

A

2 Infections
Parasitic infestations
Allergic reactions

26
Q

What are the 2 examples of infections that cause Leukocytosis?

A

Bacterial

Some Viral

27
Q

Among all the causes, which cause is Leukocytosis especially common in?

A

Bacterial Infection

28
Q

Which cells do most Bacterial infections induce?

A

Neutrophils

29
Q

What are examples of some Viral infections that cause Leukocytosis? (2 points)

A

Infectious Mononucleosis

Mumps

30
Q

What are examples of Parasitic infestations and Allergic reactions that cause Leukocytosis? (2 points)

A

Bronchial Asthma

Hay Fever

31
Q

Which cells are induced by Parasitic infestations?

A

Eosinophilia

32
Q

What unit is used to count the Leukocytosis?

A

cells/mm3

33
Q

What is the Leukocytosis usual range number?

A

15K-20K

34
Q

What is Leukopenia a feature of?

A

Typhoid Fever

Some Parasitic Infections

35
Q

The action of what causes Weight loss? (2 points)

A

IL-1

TNF-α

36
Q

What is the action of IL-1 and TNF-α?

A

Increase Catabolism

37
Q

What do IL-1 and TNF-α increase the Catabolism of? (3 points)

A

Muscles
Tissue
Liver

38
Q

Which muscles’ catabolism increases by IL-1 and TNF-α?

A

Skeletal

39
Q

Which tissue’s catabolism increases by IL-1 and TNF-α?

A

Adipose

40
Q

What does the increased Catabolism of these examples cause?

A

Negative Nitrogen Balance