Chapter 3 - Blood Cancers Flashcards
What is Hematopoiesis?
It is the production of blood cells
Can you name the two Lymphoid Cells?
B and T cells
What is the function of Lymphoid Cells?
Immune System
What is another name for lymphoid cells?
Lymphocytes
What are the 5 Myeloid blood cells?
- Basophil
- Neutrophil
- Monocyte ->4. Macrophage
- Eosinophil
What blood cell contributes to blood clotting?
Platelets
What blood cell contributes to the transportation of Oxygen?
Erythrocytes
A cell that is capable of self-renewal?
Stem Cells
What are stem cells of the blood called?
Hematopoietic Stem Cells
How do we use cell lineage?
You trace a line of decent from a stem cell to types of differentiated cells
As cells become more differentiated they usually become less proliferate, meaning they are?
less capable of cell division
Less aggressive Cancers=
More aggressive Cancers=
More differentiated
Less differentiated
What is considered a liquid cancer?
Leukemia
Chronic Myeloid Leukemia is characterized as:
An excess in monocytes, neutrophils, basophils, and eosinophils (all myeloid cells)
Chronic Lymphatic Leukemia is characterized as:
An excess in lymphocytes (B cells)
What is the pathology of Leukemia? (What physical characteristics)
Infection cause by lack of immune cells
Lack of platelets cause bruising and hemorrhaging
Anemia and exhaustion because of lack of red blood cells
bone fracture
What is considered Solid Tumors?
Lymphoma and Myeloma
What is Lymphoma?
When lymphocytes grow as solid tumors
The most common type of Lymphoma:
What is its characteristic?
Non-Hodgkin’s Lymphoma
B OR T cell lymphoma
Lymphoma that has a characteristic of Abnormal B cell tumors only? These cells are also called Reed-Sternberg Cells
Hodgkin’s Disease
A solid tumor of plasma cells in the bone marrow?
Myeloma
What are the two types of Myelomas?
Plasmacytoma - single tumor
Multiple myeloma - multiple tumors
What are plasma cells?
B Cells that produce antibodies
What is the excess of blood platletes?
Thrombosis
What is the excess of red blood cells?
Polycythemia Vera
What is the most common type of cancer a child can get and why?
The most common is acute lymphocytic leukemia (ALL).
- A large amount of cell division occurs in the blood and nervous system.
- These cancers only need 1 to 2 mutations to arise
