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Cancer Biology > Chapter 3 - Blood Cancers > Flashcards

Chapter 3 - Blood Cancers Flashcards

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1
Q

What is Hematopoiesis?

A

It is the production of blood cells

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2
Q

Can you name the two Lymphoid Cells?

A

B and T cells

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3
Q

What is the function of Lymphoid Cells?

A

Immune System

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4
Q

What is another name for lymphoid cells?

A

Lymphocytes

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5
Q

What are the 5 Myeloid blood cells?

A
  1. Basophil
  2. Neutrophil
  3. Monocyte ->4. Macrophage
  4. Eosinophil
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6
Q

What blood cell contributes to blood clotting?

A

Platelets

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7
Q

What blood cell contributes to the transportation of Oxygen?

A

Erythrocytes

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8
Q

A cell that is capable of self-renewal?

A

Stem Cells

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9
Q

What are stem cells of the blood called?

A

Hematopoietic Stem Cells

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10
Q

How do we use cell lineage?

A

You trace a line of decent from a stem cell to types of differentiated cells

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11
Q

As cells become more differentiated they usually become less proliferate, meaning they are?

A

less capable of cell division

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12
Q

Less aggressive Cancers=

More aggressive Cancers=

A

More differentiated

Less differentiated

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13
Q

What is considered a liquid cancer?

A

Leukemia

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14
Q

Chronic Myeloid Leukemia is characterized as:

A

An excess in monocytes, neutrophils, basophils, and eosinophils (all myeloid cells)

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15
Q

Chronic Lymphatic Leukemia is characterized as:

A

An excess in lymphocytes (B cells)

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16
Q

What is the pathology of Leukemia? (What physical characteristics)

A

Infection cause by lack of immune cells
Lack of platelets cause bruising and hemorrhaging
Anemia and exhaustion because of lack of red blood cells
bone fracture

17
Q

What is considered Solid Tumors?

A

Lymphoma and Myeloma

18
Q

What is Lymphoma?

A

When lymphocytes grow as solid tumors

19
Q

The most common type of Lymphoma:

What is its characteristic?

A

Non-Hodgkin’s Lymphoma

B OR T cell lymphoma

20
Q

Lymphoma that has a characteristic of Abnormal B cell tumors only? These cells are also called Reed-Sternberg Cells

A

Hodgkin’s Disease

21
Q

A solid tumor of plasma cells in the bone marrow?

A

Myeloma

22
Q

What are the two types of Myelomas?

A

Plasmacytoma - single tumor

Multiple myeloma - multiple tumors

23
Q

What are plasma cells?

A

B Cells that produce antibodies

24
Q

What is the excess of blood platletes?

A

Thrombosis

25
Q

What is the excess of red blood cells?

A

Polycythemia Vera

26
Q

What is the most common type of cancer a child can get and why?

A

The most common is acute lymphocytic leukemia (ALL).

  • A large amount of cell division occurs in the blood and nervous system.
  • These cancers only need 1 to 2 mutations to arise

Cancer Biology (19 decks)

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