Chapter 3 and 4 Flashcards
Conception occurs when
Sperm penetrates an ovum
At conception,
The 23 chromosomes from sperm meet with 23chromosomes from ovum to make a 23 paired cell
23 pairs of chromosomes new cell called
Zygote
Sex of baby is determined by
The mans sperm either being X(girl) or Y(male)
Fraternal / dizygotic twins
Conceived when two eggs are fertilized by 2 sperm
Can be different genders, 2 seperate babies
Identical or monozygotic twins
Single fertilized ovum separates into two parts
Have identical genes
Over last 30 years the # of multiple births has ____
Leading to rate or triplets, quadruplets, to increase over ____%
Tripled
230%
Why women over 35 have twins more?
Women are naturally more likely, no one knows why
And due to their age; they use assisted reproduction procedures (like ovum drugs)
Assisted human reproduction
Bill C6 protects women
Fertility drugs are available to couples having sexual issues
Cryopreservstion freezes multiple embryos
Artificial insenination: injects some directly into women
Pregnancy
Physical condition in which a women’s body is nurturing a developing fetus
First trimester
Conception to 12 weeks
Zygote implants itself in lining of women’s uterus
Morning sickness occurs here!!! Breast swelling
Prenatal care is essential to prevent birth defects
Greatest risk of miscarriage
All of babies organs form in the first
8 weeks
Second trimester
12-24 weeks
Women’s gains weight and uterus expands
Women’s begins to feel fetus move
Parental visits include monitoring mother and babies vitals and keeping track of wombs growth
Third trimester
25 weeks to labour
Weight gain and abnormal enlargement
Women emotionally connected to baby
Toxaemia May occur
Toxaemia
Sudden increase in blood pressure
Postpartum care / 4th trimester
Postpartum women need more care, on an ongoing basis
Women centered
Checkups moved from 6 weeks to 3
Cephalocaudal pattern
Development proceeds from head downwards
Proximodistal pattern
Development from centre of body to outside
Prenatal development stages
Germinal - embryonic - fetal
Germinal stage
First 2 weeks of gestation, from conception to implantation
Cell division rapidly happens
Words to know for this stage: placenta, umbilical cord, amnion
Placenta
Specialized organ that allows substances to be transfered from mother to embryo and embryo to mother without mixing blood
Umbilical cord
Organ that connects the embryo to placenta
Amnion
Fluid filled sac in which the fetus floats until just before it is born
Embryonic stage
Begins when implantation is complete, at about the end of 2nd week
Cells start to specialize and come together
Words to know: neurons, gonads, organogenesis
Neurons
Specialized cells of the nervous system
Gonads
Sex glands
Organogenesis
Process of organ development
Neuronal proliferation
During weeks 10-18 neutral formation picks up dramatically
Between weeks 13 and 21…
Neurons migrate to the parts of the brain where they will reside for entire lifetime
Fetal stage
Begging at end of week 8 and continuing until birth (7 months)
This stage involves refinement of the organs system, especially lungs and brain
Viability
Ability of the fetus to survive outside of the womb
By week 12
Fetus can be seen as male or female
Sex differences for males
More physically active fetus
Male embryo secretes testosterone
Subtle difference in prenatal brain development
More vulnerable to prenatal issues
More likely to be aborted
More likely to have birth defects
Prenatal behavior
Newborns remember stimuli from when in belly
Such as music, mothers heartbeat, odour from fluids
Active fetus = active child
Congenital anomaly
Abnormality present at birth
Genetica disorders
High blood pressure
Huntington’s disease
Extra fingers
Schizophrenia
Sex linked disorders
Red-green colour blindness
Hemophilia
Trisomies
Condition in which a child has three copies of a specific autosome
Most common trisomy
Trisomy 21: Down syndrome
Klinfelter syndrome
Affects boys look the same but have underdeveloped testes, low sperm production
Turners syndrome
Anatomically female but show stunted growth
Teratogens
Agents that cause damage to an embryo or fetus
Greatest risk of teratogens is in the first _____ weeks
8 weeks
As this is when organs develop
Examples of teratogens
HIV
CMV (type of herpes)
Gonorrhea
Syphilis
Mothers who use / take drugs
Very dangerous, advice doctors for drugs
Mothers who smoke during pregnancy
Lower birth weight
Have higher risk of miscarriage, stillborn, premature birth
Mothers who drink while pregnant
Can affect zygote
Produce babies with fetal alcohol syndrome (have smaller brains)
Fetal alcohol syndrome aspects
Baby has heart issues, hearing loss, distinct faces with small eyes, flat nose, long space between nose and mouth
Shorter than normal, stupid
Other factors that can affect prenatal development
Mothers diet, age, and physical and mental health
Diet
Folic acid!! Women need
Lots of calories and protein
Malnutrition = low birth weight
BMI: body mass index
Age
Women over 35 run risks of heart issues or chromosomal disorders
Chronic illnesses
Mothers with heart disease, diabetes, lupus, epilepsy can damage babies
3 broad categories or teratogens
Mutagenic
Environmental
Unknown
Mutagens
Agents that cause changes in genomic DNA
Germinal mutations
Type of mutagenic teratogens caused by radiation and chemical toxins
X rays
Environmental teratogens
Environmental agents can have direct effects on prenatal development by damaging cells, or disrupting normal cell development
Interfere with cell proliferation (increase in cells by growth and cell division) or with cell migration
Epimutagenic teratogens
Cause abnormal gene silencing or expression
Paternal influences
Father pass roughly ___% if genetic mutations
Contamination of the mother and fetus can occur through _____ or _____ entering the home
55%
Seminal fluids
Toxins
External paternal effects
Smoking in house
Physical abuse to wife
How to screen women for congenital defects?
Chorionic villus sampling (CVS)
Amniocentesis
Alpha-fetoprotein sampling
Fetoscopy
Chorionic villus sampling (CVS)
Cells extracted from the placenta
Amniocentesis
Needle extracts amninotic fluid containing fetal cells
Alpha-fetoprotein sampling
Present in blood, leads to abnormalities such as brain and spinal cord issues
Fetoscopy
Inserting tiny camera into womb to directly observe fetal development
Gestation
Process of carrying or being carried in the womb before birth
Birth choices
Midwives
Use of drugs?
In a hospital, free standing center, home delivery
Midwives
Health care professional who supervise and care for women
Conduct delivery and care for new borne
3 types of drugs to use during birth
Analgesics (reduce pain)
Sedatives / tranquilizer (reduce anxiety)
Anaesthesia (blocks pain)
Location of birth
Traditional maternity unit
Hospital birthing room
Free standing birth centre
Home delivery
Physical process of birth
Steps 1: dilation and effacement
Steps 2: actual delivery
Steps 3: afterbirth
Dialation
Opening of cervix large enough for baby to get through (10cm)
Effacement
Flattening of cervix
Stage 2
When cervix is dialated, actual delivery happens
Stage 3
After birth
Delivery of placenta and other material from uterus