Chapter 3 Flashcards
Correlate
A factor that co-varies or is associated with some outcome of interest
Risk factor
- factor or characteristic associated w increased risk of developing condition Y
- if X is shown to occur before Y, X is a risk factor for Y
Variable risk factor
- risk factor that can change within a person (eg variance in level of depression)
- In a situation where X preceeds Y, if X can be changed, it is a variable risk factor
Fixed marker
- In a situation where X preceeds Y, X is a fixed marker of Y if X cannot be changed
- eg history of abuse during childhood, race
Variable marker
- variable risk factor that, when changed, doesn’t influence outcome of interest
- if changing X does not lead to a change in Y
Causal risk factor
- variable risk factor that, when changed, changes likelihood of outcome of interest
- if changing X leads to a change in Y
Necessary cause
- characteristic (X) that MUST exist for a disorder (Y) to occur
- most mental disorders do not have necessary causes
- ex: to develop general paresis (Y) one must have previously had syphilis (X)
Sufficient cause
- a condition that guarantees the occurrence of a disorder
- one theory hypothesizes that hopelessness (X) is a sufficient cause for depression (Y): if you are hopeless enough you will become depressed
Contributory causes
- increase probability of a disorder developing but is neither necessary nor sufficient for the disorder to occur
- if X occurs, probability of Y occurring increases
Distal risk factors (or distal causal factors)
- causal factors occurring early in life that may not show effects for many years
- may contribute to predisposition to develop a disorder
Proximal risk factors
- factors that operate shortly before occurrence of symptoms of a disorder
- may be a condition that proves too much for someone and triggers the onset of a disorder
- may involve biological changes like damage to parts of left hemisphere that can lead to depression
Reinforcing contributory cause
- condition that tends to maintain maladaptive behavior that is already occurring
- eg extra attention/sympathy for ill person can unintentionally discourage recovery
Causal patterns
- when more than one causal factor is involved (eg A, B and C lead to Y)
Diathesis-Stress Models
- view of abnormal behaviour as result of a major stressor being experienced by someone who has a preexisting vulnerability for that disorder
- diathesis = predisposition toward developing a disorder (biological, psychological, or sociocultural causal factors)
Additive model
- diathesis and stress add up to lead to disorder (someone w high level of diathesis might only need a small amount of stress to develop a disorder)
Interactive model
- some amount of diathesis must be present before stress will have any effect
- effect between one variable (stress) and another (disorder) varies at different levels of the third variable (diathesis)
- see textbook 3.1.3 for graphs to help understand
Protective factors
- decrease likelihood of negative outcomes for those at risk
- not the same as absence of risk factor
- successfully dealing with a stressor (usually moderate and not mild or extreme) can turn it into a protective factor
- ex having a warm and supportive parent
Resilience
- ability to adapt successfully to even very difficult circumstances
Biopsychosocial viewpoint
- biological, psychological, and social factors all interact and play a role in psychopathology and treatment
4 categories of biological factors particularly relevant to development of maladaptive behaviour
- Genetic vulnerabilities
- Brain dysfunction and neural plasticity
- Neurotransmitter and hormonal abnormalities in the brain or other parts of the central nervous system
- temperament
Genes
- long molecules of DNA
- we have one copy of each gene from each parent
- each gene exists in 2 or more alternate forms called alleles
- genes determine broad temperamental features in newborns
- most mental disorders show at least some genetic influence
Chromosomes
- chain-like structures within cell nucleus that contain genes
- each human cell has 23 pairs of chromosomes
Down syndrome
- intellectual disability
- trisomy (3 chromosomes instead of 2) in chromosome 21
Polygenic
- mental disorder influenced by multiple genes or by multiple polymorphisms of genes
Polymorphism
- naturally occurring variations of genes
Genotype
- a person’s total genetic endowment
Phenotype
- observed structural and functional characteristics of a person that result from interaction between genotype and environment
Genotype-environment correlation
- genotypic vulnerability that can shape a child’s environmental experiences
- eg aggressive child is rejected so finds aggressive friends, becomes teenage delinquent
Passive effect of genotype on environment
- resulting from genetic similarity of parents and children
- eg smart parents provide more stimulating environment for child, creating environment that interacts in positive way with child’s genetic endowment for high intelligence
Evocative effect of genotype on environment
- child’s genotype evokes particular kinds of reactions from social and physical env.
- ex active and happy babies draw out more positive responses from others
Active effect of genotype on environment
- child seeks out or builds an environment that is congenial (“niche building”)
- ex extraverted children seek company of others, enhances social tendencies
Family history (or pedigree) method
- method used in field of behavior genetics
- examines incidence of disorder in relatives of an index case to determine whether incidence increases in proportion to the degree of the hereditary relationship
- limitation: ppl closely related more likely to share similar environment, hard to separate genetics and environment
Twin method
- method in field of behavior genetics
- compare concordance rate between identical and nonidentical twins
- concordance rates of disorders in identical twins is not 100% so no disorder is completely heritable
- evidence not conclusive bc identical twins might be treated more similarly
Adoption method
- method in field of behavior genetics
- comparison of biological and adoptive relatives with and without a given disorder to assess genetic vs environmental influences
Linkage analysis
- genetic research strategy in which occurence of a disorder in an extended family is compared with that of a genetic marker for a physical characteristic or biological process that is known to be located on a particular chromosome
- eg tracing eye color and schizophrenia
- difficulty in replicating these results