Chapter 11 Flashcards
Substance-related disorders
- using substances in excessive amounts that result in impairment
Addictive behaviour
- behaviour based on pathological need for a substance
Psychoactive substances
- substances that affect mental functioning in central nervous system
Substance abuse vs. substance dependence
- abuse: excessive use of substance resulting in potentially hazardous behavior; continued use despite problems
- dependence: more severe forms of substance use disorders
Tolerance
- need for increased amounts of substance to achieve desired effects
Withdrawal
- physical symptoms (like sweating) that accompany abstinence from a drug
Alcohol use disorder
- use of alcohol even though there are detrimental effects associated with it
- brain shrinkage leads to worsening cognitive abilities
- found across all age, educational, occupational, and SES backgrounds
- high comorbidity between alcohol use and mental illness/other substance abuse disorders
- avg. lifespan is 12y shorter
U.S. Prevalence - Alcohol Use Disorder
- 30% meet diagnostic criteria at least once in their life (nearly 15% in a given year)
- > 50% 18+ drink alcohol; 27% report binge drinking
- 2x as common in men
- Native Americans > Black/whites > Asian Americans
Is alcohol a stimulant or a depressant?
- alcohol is both a nervous system stimulant (low doses) and depressant (high doses)
Rates of alcohol abstainers in US
- 28% of men
- 50% of women
Alcohol vs heroin withdrawal
- alcohol withdrawal potentially more lethal than opiate withdrawal!
BAC
- 0.08%: no driving
- 0.5%: pass out
- 0.55%+: usually lethal
Effects of alcohol on the brain
- low levels stimulate release of dopamine from pleasure centers
- high levels depress brain function/inhibit glutamate (impairments in judgement, motor coordination, etc)
Development of alcohol dependence
- early-to middle-to late-stage
- often starts with slight problem drinking behavior, increases in frequency and intensity over time
Physical effects of chronic alcohol use
- 15-30% of heavy drinkers develop cirrhosis of the liver
- excessive use may lead to malnutrition (may choose substance over food)
Psychosocial effects of alcohol abuse and dependence
- chronic fatigue
- oversensitivity
- depression
- impaired reasoning
- personality deterioration
Hangovers!
- peaks when BAC approaches 0
- ppl with these disorders may drink again to avoid hangover
Alcohol withdrawal delirium
- alcohol abuse related psychosis
- follows prolonged drinking spree when person enters state of withdrawal for 3-6 days
- hallucinations, acute fear, fever, rapid/weak heartbeat
- followed by deep sleep
- increased risk of death
Alcohol amnesiac disorder
- memory defect sometimes accompanied by falsification of events
- delusions connected to trying to fill in memory gaps
- symptoms result from malnutrition (lack of vitamin B–treated with thiamine)
- reversible if treated within the first few days
Biological causes of alcohol use disorder
- addictive drugs activate mesocorticolimbic dopamine pathway (“pleasure pathway”); drugs that activate this are a potential candidate for abuse
- genetics play a role in vulnerability, not sure exactly how, might be bc of dysfunction in reward pathway
- 2x risk in late 20s if biological parent has alcohol use disorder
Psychosocial causes of alcohol use disorder
- family dysfunction (lack of stable relationships)
- exposure to negative models
- these two might have bidirectional effect
- often correlated w mental disorders
- exposure to trauma correlated w alcohol use; ppl might use to reduce stress
- teens begin drinking bc they think alcohol will increase popularity
- might begin during crisis periods of relationship; excessive drinking can also contribute to divorce
- cultural attitudes influence incidence
Medications in Treating Alcohol Abuse and Dependency
Meds to block desire to drink:
- Disulfiram (Antabuse) causes vomiting when followed by alcohol
- Naltrexone helps reduce cravings for alcohol
- Acamprosate
Meds to reduce withdrawal side-effects:
- tranquilizers have been used
- Valium in hospitals
- concern this does not promote long-term recovery
Behavioral and Cognitive-Behavioral Therapy (alcohol use disorders)
Tools to change behavior
- aversive conditioning methods (condition noxious stimuli with drinking)
- provide life and coping skills to reduce use in future
- self-control techniques aimed at reducing intake
“Controlled drinking”
- highly controversial
- more successful in people with less severe alcohol problems
- abstinence associated w greater success (after you’ve had one drink your judgment is impaired, harder to resist another)