CHAPTER 29 Flashcards
DIAGNOSING INFECTIOUS DISEASE
a reaction between antibody and particle-bound antigen resulting in visible clumping of the particles
AGGLUTINATION
growth media that allow identification of microorganisms based on phenotypic properties
DIFFERENTIAL MEDIA
a test that uses antibodies or antigens linked to enzymes to detect antigens or antibodies in body fluids
ENZYME IMMUNOASSAY (EIA)
an antibody molecule covalently modified with a fluorescent dye that makes the antibody visible under fluorescent light
FLUORESCENT ANTIBODY
an infection acquired by a patient in a healthcare facility, particularly during a stay in the facility. Also called a nosocomial infection.
HEALTHCARE-ASSOCIATED INFECTION (HAI)
the use of labeled antibodies to detect specific proteins after separation by electrophoresis and transfer to a membrane
IMMUNOBLOT (WESTERN BLOT)
the smallest amount of an antimicrobial substance that prevents growth of the target microorganisms
MINIMUM INHIBITORY CONCENTRATION (MIC)
a single type of antibody made by a single B cell hybridoma clone
MONOCLONAL ANTIBODY (mAb)
clinical testing that produces a clear medical result and a treatment plan within the same clinical visit
POINT-OF-CARE DIAGNOSTICS
a reaction between antibody and a soluble antigen resulting in an visible, insoluble complex
PRECIPITATION
culture media that allow the growth of certain organisms while inhibiting the growth of others through one or more added media components
SELECTIVE MEDIA
the lowest amount of antigen that can be detected by a diagnostic test
SENSITIVITY
the study of antigen-antibody reactions in vitro
SEROLOGY
the ability of a diagnostic test to identify a specific pathogen
SPECIFICITY
the number of individual particles of a substance, such as antibodies or infectious virions, per unit volume of a solution
TITER
