Chapter 26 Phatho Flashcards
1
Q
- What interstitial lung disease also goes by?
A
ILD, diffuse interstitial lung disease, fibrotic interstitial lung disease, pulmonary fibrosis, pneumoconiosis.
2
Q
- ILD refers to?
A
a broad group of inflammatory lung disorders
3
Q
- ILD can be?
A
acute, subacute, or chronic inflammatory inflammatory infiltration of alveolar walls by cells, fluid, and connective tissue
4
Q
- If ILD is left untreated it can develop into
A
irreversible pulmonary fibrosis.
5
Q
- Anatomic alteration of the lungs w/ ILD?
A
- destruction of the AC membrane
- fibrotic thickening of the respiratory bronchioles, alveolar ducts, and alveoli.
- granulomas
- honeycombing and cavity formation
- fibrocalcific pleural plaques - mainly from asbestosis
- bronchospasm
- excessive bronchial secretions , caused by inflammation
6
Q
- Groups of ILD etiology
A
- occupational/environmental
- connective tissue disease
- idiopathic interstitial pneumonia
- specific pathology
- miscellaneous
7
Q
- What are the Pathologic or Structural changes?
A
- Destruction of the alveoli and adjacent pulmonary capillaries? in Exam
- Fibrotic thickening of the respiratory bronchioles, alveolar dusts, and alveoli? in Exam
- Granulomas
- Honeycombing or cavitation formation.
- Fibrocalcific pleural plaques (asbestosis)
- Bronchospasm.
- Excessive bronchial secretions (Inflammation in airways
only)
8
Q
- What are the Etiology and Epidemiology?
Interstitial lung Diseases of known causes or Associations:
A
Occupational, Environmental, and Therapeutic Exposures:-
- Inorganic particulate dust exposure.
- Coal dust
- Silicosis
- Beryllium
- Organic material exposure.
- Medications and illicit drugs
- Radiation therapy.
9
Q
- What is the SYSTEMIC DISEASES?
A
Connective Tissue Diseases (Collagen Vascular)
- Scleroderma
- Rheumatoid arthritis
- Sjogren’s syndrome
- Polymyotis-dermatomyositis.
- Systemic lupus erthematosus.
- Sarcoidosis.
10
Q
- What are Idiophathic Interstitial Pneumonias?
A
- Idiopathic Pulmonary fibrosis.
- Cryptogenic Organizing Pneumonia.
- Lymphocytic Interstital Pneumonia
11
Q
- What is the Specific Pathology?
A
- Lymphangioleiomyomatosis (LAM)
- Pulmonary Langerhans Cell Histiocytosis.
- Pulmonary Alveolar Proteinosis.
- Pulmonary Vasculitides.
. Wegener’s granulomatosis
. Churg-Strauss syndrome.
. Lymphomatoid granulomatosis
12
Q
- What is Miscellaneous Diffuse Interstitial Lung Diseases?
A
- Goodpasture’s Syndrome
- Idiopathic Pulmonary Hemosiderosis.
- Chronic Eosinophilic Pneumonia
13
Q
- What is General Management of Interstitial Lung Disease?
A
- Corticosteroids
- O2 Therapy
- Mechanical ventilation
- Plasmaphereis (Goodpasture’s Syndrome)