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Patho Test 3-me > Chapter 25- Structure and Function of the Hematologic System > Flashcards

Chapter 25- Structure and Function of the Hematologic System Flashcards

1
Q

Which is not a plasma component?

a. colloids
b. electrolytes
c. gases
d. glucose
e. platelets

A

e. platelets

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2
Q

Which is the most abundant protein in blood plasma?

a. fibrinogen
b. albumins
c. glubulins
d. immunoglobulins
e. hormones

A

b. albumins

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3
Q

A fragment of megakaryocytic cytoplasm is the:

a. reticulocyte
b. normoblast
c. promyelocyte
d. proerythroblast
e. platelet

A

e. platelet

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4
Q

Mast cell mediators are available to:

a. vascular endothelial cells
b. nerves
c. immune cells
d. a & c are correct
e. a,b,c are correct

A

e. a,b,c are correct

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5
Q

Identify the differentiation pathway in the development of erythrocytes.

a. uncommitted pluripotential stem cell-normoblast-reticuloyte
b. normoblast-reticulocyte-basophalic erythroblast
c. normoblast-committed pro erythroblast-reticulocyte
d. normoblast-basophilic erythroblast-reticulocyte

A

a. uncommitted pluripotential stem cell-normoblast-reticuloyte

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6
Q

A differential count of abcs includes all of the following except:

a. granulocytes
b. agranulocytes
c. reticulocytes
d. monocytes
e. lymphocytes

A

c. reticulocytes

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7
Q

The main regulator of platelet circulating mass is:

a. GP IIb/IIIa complex
b. ADP
c. Thrombopoietin
d. thromboxane

A

c. Thrombopoietin

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8
Q

The normal platelet count/mm^3 of blood is about

a. 4 to 10 X 10^3
b. 50 to 100 X 10 ^3
c. 140 to 340 X 10^3
d. 5 X 10^6
e. 150 to 300 X 10^6

A

c. 140 to 340 X 10^3

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9
Q

The hematocrit is the

a. number of RBCs in plasma
b. aqueous portion of the blood
c. criterion of the blood flow
d. percentage of RBCs in a given volume of blood
e. amount of hemoglobin by weight in blood

A

d. percentage of RBCs in a given volume of blood

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10
Q

If the total leukocytic count of an individual was 7000/mm, about how many neutrophils would normally be present in a mm of blood?

a. 400
b. 700
c. 2100
d. 3000
e. 4200

A

e. 4200

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11
Q

Which of the granulocyte functions in antibody-mediated defense against parasites

a. lymphocyte
b. monocyte
c. neutrophil
d. eosinophil
e. basophil

A

d. eosinophil

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12
Q

About how many times more RBCs than WBCs are there in a mm of blood

a. 15
b. 90
c. 100
d. 1000
e. none of the above is correct

A

d. 1000

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13
Q

Which is an a granulocyte?

a. basophil
b. lymphocyte
c. neutrophil
d. polymorph

A

b. lymphocyte

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14
Q

Which are the most effective phagocytes

a. neutrophils & basophils
b. lymphocytes and eosinophils
c. basophils and monocytes
d. neutrophils and monocytes
e. none of the above

A

d. neutrophils and monocytes

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15
Q

Erythropoiesis requires vitamins

a. C & E
b. B2 & B12
c. A & D
d. Both a & b
e. A, B, C are correct

A

d. Both a & b

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16
Q

Nitric oxide and prostacyclin

a. inhibit platelet adhesion & aggregation
b. are vasoconstrictions
c. are produced by erythrocytes
d. are sporadically produced

A

a. inhibit platelet adhesion & aggregation

17
Q

Which test reflects bone marrow activity?

a. reticulocyte count
b. mean corpuscular hemoglobin (MCH)
c. mean corpuscular volume (MCV)
d. hematocrit (HCT)

A

a. reticulocyte count

18
Q

As an individual ages:

a. the erythrocyte lifespan is shortened
b. lymphocytic function decreases
c. platelet numbers decrease
d. all of the above are correct

A

b. lymphocytic function decreases

19
Q
  1. Which of the following is TRUE regarding the constituents of blood?
    A. Plasma is composed of 90% dissolved substances and 10% water.
    B. Blood volume in adults is about 6 L.
    C. Plasma accounts for 10% of blood volume.
    D. Plasma and serum are identical.
A

B. Blood volume in adults is about 6 L.

20
Q 
2. Which component of the blood system is responsible for the critical colloid oncotic pressure?
A. Immune globulins
B. Albumin
C. Gamma globulin
D. Clotting factors
A

B. Albumin

21
Q
  1. Which of the following is TRUE regarding Erythrocytes?
    A. They comprise 80% of blood volume.
    B. Erythrocytes are responsible for tissue oxygenation.
    C. They contain ribosomes and mitochondria.
    D. They can synthesize proteins
A

B. Erythrocytes are responsible for tissue oxygenation.

22
Q 
4. Which of the following is NOT a granulocyte?
A. Neutrophil
B. Basophil
C. Eosinophil
D. Monocyte
A

D. Monocyte

23
Q 
5. A person develops a severe urinary tract infection. Which of the following are the predominant cells of early inflammation?
A. Monocyte
B. Neutrophil
C. Basophil
D. Eosinophil
A

B. Neutrophil

24
Q 
6. A student looking at a slide notices large cells with a horseshoe-shaped nucleus and no granules present. Which of the following cells are these?
A. Monocytes
B. Macrophages
C. Lymphocytes
D. Natural killer cells
A

A. Monocytes

25
Q
  1. Which of the following is TRUE regarding platelets?
    A. They are disk-shaped cytoplasmic fragments.
    B. They are formed by clumps of megakaryocytes.
    C. They have a large nucleus.
    D. They divide rapidly.
A

A. They are disk-shaped cytoplasmic fragments.

26
Q 
8. Which of the lymphoid organs cluster around lymphatic veins and collect interstitial fluid from tissues?
A. Spleen
B. Bone marrow
C. Lymph nodes
D. Thymus
A

C. Lymph nodes

27
Q 
9. Which of the following is NOT one of the four processes of platelet activation?
A. Adhesion
B. Aggregation
C. Secretion
D. Inhibition
A

D. Inhibition

28
Q 
10. Which of the following is responsible for lysis or the breakdown of blood clots?
A. Nitric oxide
B. Tissue factor
C. Antithrombin III
D. Fibrinolytic system
A

D. Fibrinolytic system

29
Q 
Match the colony-stimulating factor with the cells that are stimulated.
IL-3
a. erythrocyte
b. pluripotent stem cell
c.macrophage, fibroblast, neutrophil
d. normoblast
e. erythroblast
A

b. pluripotent stem cell

30
Q 
Match the colony-stimulating factor with the cells that are stimulated.
G-CSF
a. erythrocyte
b. pluripotent stem cell
c.macrophage, fibroblast, neutrophil
d. normoblast
e. erythroblast
A

c.macrophage, fibroblast, neutrophil

31
Q

In the coagulation cascade, _______ is the primary cellular initiator of blood coagulation at the injury/wound site.

A

tissue factor

32
Q

After the vessel injury, the ______ complex leads to platelet activation and fibrin deposition.

A

TF-FVIIa

33
Q

In the fibrinolytic system, _____ is released from perturbed endothelial cells near the site of vascular injury and converts plasminogen to plasmin.

A

tissue plasminogen activator (t-PA)

34
Q

Both t-PA and plasminogen bind to _______, causing plasmin generation and localized ________.

A

fibrin, fibrinolysis

Patho Test 3-me (10 decks)

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