chapter 24 urinary system Flashcards

1
Q

represent the functional unit of the kidney

A

nephrons

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2
Q

the function of a kidney is to

A

filter the blood and form urine and maintain homeostasis of body fluids”;

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3
Q

blind, cup-shaped end of a renal tubule that completely surrounds the glomerulus

A

Glomerular (Bowman’s) capsule

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4
Q

composed of cuboidal cells with numerous microvilli and mitochondria

A

Proximal tubule

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5
Q

Proximal tubule

functions

A

Functions primarily for selective reabsorption of solutes (especially, nutrients, such as glucose, amino acids, vitamins, etc.)
 Selective reabsorption moves solutes from the filtrate and back into the blood stream

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6
Q

a long, hairpin-shaped loop of the renal tubule

A

Nephron loop (Loop of Henle

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7
Q

Nephron loop (Loop of Henle functions

A

Functions to concentrate extracellular fluid in the medullary tissue

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8
Q

from the proximal tubule

A

Descending limb

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9
Q

leads to distal tubule

A

Ascending limb

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10
Q

cuboidal cells that mostly lack the abundant microvilli

A

Distal tubule

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11
Q

Distal tubule

functions

A

The DCT functions more in tubular secretion than in reabsorption
 Tubular secretion involves the movement of solutes from the bloodstream into the filtrate or forming urine
 Substances that are secreted across the DCT include ions such as K+ and H+, organic dyes, certain antibiotics, etc.

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12
Q

Receive filtrate from nephrons

 Run through the medullary pyramids

A

Collecting ducts

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13
Q

Collecting ducts

functions

A

Collecting ducts function primarily for the selective reabsorption of water from the forming urine; movement of water from the filtrate back into the interstitial fluids results mostly from osmosis
 Permeability of the collecting duct to water molecules is facilitated by the influence of ADH from the posterior pituitary gland
 Collecting tubules converge to form papillary ducts, which deliver urine to minor calyces

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14
Q

small artery that supplies an individual nephron

A

Afferent arteriole

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15
Q

(Glomerular capsule containing a glomerulus)

A

Renal corpuscle

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16
Q

a high-pressure, capillary tuft that is supplied by the afferent arteriole and which occurs within the glomerular capsule; this capillary is specialized for filtering the blood, forming glomerular filtrate, which is then processed by the remainder of the nephron to form urine;

A

Glomerulus

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17
Q

a small blood vessel that drains the glomerulus and supplies the peritubular capillary

A

Efferent arteriole

18
Q

low-pressure capillary specialized for reabsorption of water, nutrients, and other materials and tubular secretion of other materials

A

Peritubular capillary

19
Q

long, straight efferent arterioles, capillaries, and venules of juxtamedullary nephrons which extend into the renal medulla and surround the loop of Henle

A

Vasa recta

20
Q

Flow Chart

A
 Blood in arteriole
 Glomerulus
o 99% of filtrate now enters efferent arteriole, then peritubular capillary bed, then venules
o 1% of the filtrate continues its flow through the nephron
 Glomerular capsule
 Proximal tubule
 Descending limb of nephron loop
 Ascending limb of nephron loop
 Distal tubule
 Collecting duct
 Papillary duct
 Minor calyces
 Major calyces
 Renal pelvis
 Ureter
21
Q

The filtrate:

 Contains all plasma components except

A

protein

22
Q

Urine formation and adjustment of blood composition involves three major processes:

A

Glomerular filtration
 Tubular reabsorption
 Tubular secretion

23
Q

The glomerulus is more efficient than other capillary beds because:

A

Its filtration membrane is significantly more permeable
 Glomerular blood pressure is higher
 It has a higher net filtration pressure

24
Q

Plasma proteins are not filtered and are used to maintain

A

osmotic pressure of the blood

25
Q

Glomerular Filtration Rate is directly proportional to the Net Filtration Pressure
 If the GFR is too high:

A

Needed substances cannot be reabsorbed quickly enough and are lost in the urine

26
Q

Glomerular Filtration Rate is directly proportional to the Net Filtration Pressure
If the GFR is too low

A

Everything is reabsorbed, including wastes that are normally disposed of

27
Q

Three mechanisms control the GFR

A
Renal autoregulation (intrinsic system)
 Neural controls
 Hormonal mechanism (the renin-angiotensin system)
28
Q

Autoregulation entails two types of control

responds to changes in pressure in the renal blood vessels

A

Myogenic mechanism

29
Q

Autoregulation entails two types of control

senses changes in NaCl concentration

A

Tubuloglomerular feedback

30
Q

Hormonal: Renin-Angiotensin Mechanism:

 Is triggered when specific cells in the kidney release

A

renin

31
Q

Renin acts on angiotensinogen to release

A

angiotensin I

32
Q

Angiotensin I is converted to

A

angiotensin II

33
Q

Angiotensin II:
 Causes mean arterial pressure to ?
 Stimulates the adrenal cortex to release?
 As a result, both systemic and glomerular hydrostatic pressure?

A

rise
aldosterone
rise

34
Q

Neural control:
 When the sympathetic nervous system is at rest:
 Renal blood vessels are ?
 Autoregulation mechanisms

A

maximally dilated

prevail

35
Q

neural control
Under stress:
 Norepinephrine is released by the ?
 Epinephrine is released by the ?
Afferent arterioles constrict and filtration is inhibited
 The sympathetic nervous system also stimulates the ?

A

sympathetic nervous system
adrenal medulla
renin-angiotensin mechanism

36
Q

A process where most tubule contents are returned to the blood

A

Step 2 of Urine Formation: Tubular Reabsorption

37
Q

Step 2 of Urine Formation: Tubular Reabsorption
All organic nutrients are ?
Water and ion reabsorption is?
 Reabsorption may be an active (requiring ATP) or passive process

A

reabsorbed

hormonally controlled

38
Q

Loop of Henle reabsorbs

A

H2O in the descending limb

 Several types of solutes in the ascending limb

39
Q

During glomerular filtration, is the main force pushing water and solutes out of the blood and across the filtration membrane.

A

glomerular hydrostatic pressure (the glomerular blood pressure)

40
Q

GHP = glomerular hydrostatic pressure

GHP is opposed by 2 forces that drive fluids back into capillaries:

A
  1. Colloid osmotic pressure of glomerular blood (GCOP)
     Colloid osmotic pressure = Pressure created by large nondiffusible molecules
  2. Capsular hydrostatic pressure (CHP) exerted by fluids in the capsule