chapter 10 part 2 muscular system needs to be reviewed missing info Flashcards
Depolarization & Generating an Action Potential
1. Na+ enters the cell, and the resting potential is?
2.If the stimulus is strong enough, an action potential is?
- decreased
2. initated
Propagating the Action Potential
- Polarity reversal of the initial patch of sarcolemma changes the ?
- Voltage-regulated Na+ channels now ?in the adjacent patch causing it to ?
- Thus, the action potential travels rapidly along the ?
- Once initiated, the action potential is? and ultimately results in the contraction of a ?
- permeability of the adjacent patch
- open, depolarize
- sarcolemma
- unstoppable, muscle
Repolarization
1. Immediately after the depolarization ? passes,the sarcolemma permeability ?
2.?channels close and ?channels open
3. ?diffuses from the cell, restoring the ?
4.?occurs in the same direction as depolarization, and must occur before the?
5.The ionic concentration of the resting state is restored by the ?
6.A brief action potential of 1-2 ms leads to contraction for ~100+ms
7.Action potential is over long before signs of muscle action are obvious.
8. During this latent period between initiation of action potential and the beginning of muscle
shortening, what occurs.
- wave, changes
- Na+, K+
3.K+, electrical polarity of the sarcolemma - repolarization, muscle can be stimulated again (refractory period)
5.Na+-K+ pump
6.
7.
8.excitation-contraction coupling
the final trigger for contraction is
Rise in intracellular Ca2+ levels
is the sequence of events that leads to sliding of
myofilaments to shorten the muscle.
Excitation-contraction coupling
The three phases of a muscle twitch are:
Latent period – first few milliseconds after stimulation when excitation-contraction
coupling is taking place
Contraction period – cross bridges actively form and the muscle shortens
Relaxation period – Ca2+ is reabsorbed into the SR, and muscle tension goes to zero
Muscle contraction can be graded in 2 ways:
- by changing frequency of stimulation
2. by changing strength of stimulus