Chapter 24: Lymphatic System Flashcards
What are the functions of the lymphatic system
(4 functions)
- Return interstitial fluid back to the bloodstream
- Transport lipids and lipid-soluble vitamins into the bloodstream
- Production and maturation of lymphocytes
- Generate an immune response against antigens in the interstitial fluid
What are the components of the Lymphatic System
(8 components)
- Lymph
- Lymphatic capillaries
- Lymphatic vessels
- Lymphatic trunks
- Lymphatic ducts
- Lymphatic cells
- Lymphatic nodules
- Lymphatic organs
What is a lymph comprised of
- Interstitial fluid
- Solutes
- Foreign materials
Life cycle & name changes of a lymph:
- ________ flowing in blood capillaries is pushed out of capillaries by blood pressure
Plasma
Life cycle & name changes of a lymph:
- Once out of the capillaries, plasma becomes mixed with ________ _____ surrounding all of the cells
Interstitial fluid
Life cycle & name changes of a lymph:
- When taken up by lymphatic capillaries it becomes _______ and it passes through lymphatic ‘vessels’ to ________ _____ where it is filtered and where immune cells detect _______.
lymph; lymph nodes; antigens
Life cycle & name changes of a lymph:
- Lymphatic vessels merge to form ______ which fuse to become _____
trunks; ducts
Life cycle & name changes of a lymph:
- Returned by one of two lymphatic ducts to the subclavian veins where it is again called _____.
plasma
closed-ended tubes that are found interspersed among most blood capillary beds.
Lymphatic capillaries
Resemble blood capillaries but they have overlapping endothelial cells that act as one-way valves allowing interstitial fluid a one-way entrance into this type of capillary:
Lymphatic capillaries
Describe Lacteals
lymphatic capillary that collects interstitial fluid as well as lipids and lipid-soluble vitamins
Where are lacteals found?
GI tract
Lymph collected from GI system has a milky color due to the lipid absorption called _____
chyle
Lymphatic capillaries merge to form _______ _______
lymphatic vessels
How are lymphatic vessels similar to venules?
They have components of all three vascular tunics and possess valves similar to veins
Describe afferent lymphatic vessels
Bring lymph to a lymph node
Describe efferent lymphatic vessels
transport filtered lymph away from the lymph node
Lymphatic vessels merge to form left and right ___________ __________
lymphatic trunks
Three types of left and right trunks:
- Jugular trunks
- Subclavian trunks
- Bronchomediastinal trunks
Which lymphatic trunk drains lymph from the head and neck?
Jugular trunks
Which lymphatic trunk drains lymph from upper limbs
Subclavian trunks
Which lymphatic trunk drains lymph from breasts?
subclavian trunks
Which lymphatic trunk drains lymph from the superficial thoracic wall
subclavian trunks
Which lymphatic trunk drains lymph from deep thoracic structures.
bronchomediastinal trunks
Which lymphatic trunk drains lymph from most abdominal structures
Intestinal trunks
Which lymphatic trunk drains lymph from lower limbs
Lumbar trunks
Which lymphatic trunk drains lymph from the abdominopelvic wall
Lumbar trunks
Which lymphatic trunk drains lymph from pelvic organs.
Lumbar trunks
As lymphatic trunks fuse, they form ______ ______.
Lymphatic ducts
Which lymphatic vessel is located deep to the right clavicle and returns at the junction of the right subclavian and internal jugular veins. Then returns lymph from the right side of the head and neck, right upper limb and the right side of the thorax
right lymphatic duct
Largest lymphatic vessel
thoracic duct
duct that begins just inferior to the diaphragm as a rounded saclike structure called cisterna chyli
Thoracic duct
The thoracic ducts have a rounded sac-like structure just inferior to the diaphragm called the _____ _____.
cisterna chyli
The thoracic duct passes through the aortic opening of the diaphragm and returns into the junction between the left ______ and ______ ______ veins.
subclavian; internal jugular
_______ _______ collects lymph from most of the body.
Thoracic duct
Oval clusters of lymphatic cells with some extracellular matrix but not surrounded by a connective tissue capsule
lymphatic nodules
The center of a nodule is called the ______ _______, which contains _____________ and ____________.
germinal center; ß-lymphocytes; macrophages
______________ are located outside the germinal center
T-lymphocytes
What do lymphatic nodules do?
filter and attack antigens
List the different forms of lymphatic nodules:
- Lymphatic nodules
- MALT (including Peyer patches)
- Tonsils
Which lymphatic nodules are located in the mucosa (inner layer) of the gastrointestinal tract
MALT
Which lymphatic nodules are located in the mucosa (inner layer) of the respiratory tract
MALT
Which lymphatic nodules are located in the mucosa (inner layer) of the genital tracts
MALT
Which lymphatic nodules are located in the mucosa (inner layer) of the urinary tract
MALT
What does Mucosa-Associated Lymphatic Tissue (MALT) do?
monitors and responds to antigens that may enter via, food, air, or urine
MALT nodules very prominent in the ileum are referred to as ________ ________.
Peyer patches
Where are tonsils located?
mainly in the Pharynx
Located in pharynx: Large clusters of lymphatic cells and extracellular matrix that do not have completed surrounding capsules are called _______
tonsils
Tonsils outer edges are invaginated to form crypts, which allow for trapping of ________ to be presented to the lymphocytes.
antigens
What are the three types of tonsils:
- Pharyngeal tonsils
- Palatine tonsils
- Lingual tonsils
These tonsils are located in the posterosuperior wall of the nasopharynx
Pharyngeal tonsils
These tonsils are located in the posterolateral wall of the oral cavity
Palatine tonsils
These tonsils are located along the posterior one-third of the tongue
lingual tonsils
_____________ _________ consists of lymphatic cells and extracellular matrix and is completely surrounded by a connective tissue capsule
Lymphatic organs
List the three main lymphatic organs:
- Thymus
- Lymph nodes
- Spleen
Which lymphatic organ is a bilobed organ located superficial to the heart
Thymus
Which lymphatic organ consists of two fused thymic lobes, which are divided into lobules
Thymus
The thymus consists of two fused ______ _____ which are divided into ________
thymic lobes; lobules
In the Thymus, each lobule has an outer ______ and an inner ______
cortex; medulla
Which lymphatic organ continues to grow until puberty and then begins to regress in size and function and, in adults, becomes replaced mostly by adipose CT
Thymus
Which lymphatic organ is the site of T-lymphocyte differentiation and maturation
Thymus
Which lymphatic organ has a cortex that contains immature T-lymphocytes
Thymus
Which lymphatic organ has a medulla that contains mature T-lymphocytes
Thymus
At the Thymus, the cortex contains _______ T-lymphocytes, while the medulla contains ________ T-lymphocytes.
immature; mature
True or False:
At the Thymus, in adulthood T-lymphocytes can only be produced by cell division.
True
True or False:
At the Thymus, in adulthood T-lymphocytes can only be produced by maturation of new cells in the thymus
False
Which lymphatic organ are small, kidney-shaped organs that cluster around lymphatic vessels
Lymph nodes
There are (hundreds/thousands/millions) of lymph nodes within the body
Hundreds
What three areas within the body will you find large concentrations of lymph nodes:
- Neck
- Armpit
- Groin
What do lymph nodes do?
cleanse the lymph traveling within lymphatic vessels
A lymph node is surrounded by an outer capsule. Internally, the lymph node consists of an outer _______ and an inner ______.
cortex; medulla
In lymph nodes, the cortex contains many _______ _______
lymphatic nodules
In lymph nodes, the medulla collects the ______ after it passes the cortex.
lymph
Which lymphatic organ initiates an immune response when antigens are found in the blood
Spleen
Which lymphatic organ serves as a reservoir for erythrocytes and platelets
spleen
Which lymphatic organ phagocytizes old, defective erythrocytes and platelets
Spleen
Which lymphatic organ phagocytizes bacteria and other foreign materials
spleen
Which lymphatic organ monitors blood for antigens
spleen
Which lymphatic organ is the largest lymphatic organ in the body, located just lateral to the left kidney
Spleen
Which lymphatic organ is surrounded by dense irregular CT, called capsule
Spleen
What is the inner layer of the spleen called
white pulp
What is the outer layer of the spleen called
red pulp
The inner layer of the spleen, white pulp, is associated with (arterial/venous) supply.
arterial
The outer layer of the spleen, red pulp, is associated with (arterial/venous) supply.
venous
In the spleen the (inner/outer) layer, the (red/white) pulp is composed of clusters of T- and B- lymphocytes and macrophages
inner; white
In the spleen the (inner/outer) layer, the (red/white) pulp is composed of splenic cords & sinusoids, contains erythrocytes, platelets, macrophages, and some plasma cells
outer; red
Which lymphatic organ can blood cells easily enter and leave the blood stream because of the discontinuous basal lamina of the capillaries?
Spleen