Chapter 21: Blood Flashcards
What is the Function of Blood?
- Transportation of….
- Regulation of…..
- Protection by…..
- Transportation of oxygen, carbon dioxide, nutrients, and waste products.
- Regulation of body temperature , pH, and fluid volume
- Protection by mounting an immune response and the production of antibodies
Composition of Blood ( 3 fractions)
- Erythrocytes
- Buffy Coat
- Plasma
% Total Blood Volume of:
1) Erythrocytes
2) Buffy Coat
3) Plasma
1) 44%
2) 1%
3) 55%
What is the weight % composition of Plasma
- 92% = water
- 1% = electrolytes
- 7% = Plasma Proteins
Four different classes of plasma proteins:
- Albumins
- Globulins
- Fibrinogen
- Regulatory
Function of Albumins
regulates water movement, transports hormones & lipids
3 Types and Function of Globulins
- Alpha & Beta: transport water-insoluble molecules
- Gamma globulin (immunoglobulins) are antibodies
Function of Fibrinogen
converts into fibrin to make clots
Regulatory plasma proteins consist of
Proenzymes & hormones
Define hematocrit
the volume % of all formed elements in one’s blood
What are the formed elements in one’s blood:
Erythrocytes, Leukocytes, and Platelets
This formed element is often referred to as red blood cells or RBC’s
Erythrocytes
Lifespan of erythrocytes
120 days
lifespan of platelets
8-10 days
lifespan of leukocytes
12 hours to years
Relatively small formed element (7.5 µm in diameter)
Erythrocytes
This formed element has a unique bioconcave shape
Erythrocytes
Formed element that line up in single file as they pass through small blood vessels. Termed rouleau.
Erythrocytes
This formed element contains hemoglobin
Erythrocytes
___________ is capable of reversibly transporting oxygen and carbon dioxide in the blood.
Hemoglobin
Hemoglobin consists of four globin protein molecules:
- 2 alpha chains
- 2 beta chains
Each of the four globins possesses a nonprotein ________ group containing an ______ molecule
heme; iron