Chapter 24 - Lymphatic System Flashcards

1
Q

Pathogens

A

disease producing microbe

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2
Q

Immunity

A

Ward off the disease or damage

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3
Q

Susceptibility

A

lack of resistance

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4
Q

Innate Immunity

A

born with

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5
Q

Adaptive Immunity

A

specific recognition of a microbe

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6
Q

Functions of the Lymphatic System

A

-transports fluid and helps fight infection
-transport dietary lipids
-aid in the production and maturation of lymphocytes
-generates an immune response against antigens

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7
Q

Interstitial Fluid

A

that leaks out of blood capillaries enters lymph vessels

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8
Q

Lymph

A

fluid that enters vessels

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9
Q

Lymph Vessels

A

return the fluid to venous circulation

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10
Q

Edema

A

-accumulation of lymph that causes swelling

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11
Q

Lacteals

A

specialized lymphatic capillaries that absorb lipids in the intestine

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12
Q

Lymphocytes and Macrophages

A

-monitor body for foreign substances
-some produce antibodies that bind to pathogens
-some cells attach to antigen directly
-other cells create a memory of the antigen

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13
Q

Avascular Tissues

A

lack lymphatic capillaries

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14
Q

Chyle

A

lymph in lacteals

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15
Q

Valves

A

ensure lymph always moves towards the heart

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16
Q

Pathway of Lymph

A

from lymphatic capillaries into lymphatic vessels and then through lymph nodes

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17
Q

Lymph Trunks

A

uniting of lymphatic vessels

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18
Q

Final destination of lymph

A

jugular and subclavian vein in heart?

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19
Q

Jugular Trunks

A

head and neck

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20
Q

Subclavian Trunks

A

upper limbs, breasts, superficial throacic wall

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21
Q

Bronchomediastinal Trunks

A

deep thoracic structures

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22
Q

Intestinal Trunk

A

most abdonmial structures

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23
Q

Lumbar Trunks

A

lower limbs, abdominopelvic wall and pelvic organs

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24
Q

Lymphatic Ducts

A

form from the fusion of lymphatic trunks

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25
Right Lymphatic Duct
deep to the clavicle and returns at the junction of the right subclavian and internal jugular veins
26
Thoracic Duct
-the largest lymphatic vessel -collects lymph from most of the body -passes through diaphragms aortic opening and returns lymph to the junction between the left subclavian and internal jugular veins
27
Cisterna Chyli
rounded saclike structure where the thoracic duct begins
28
Where does thoracic duct not collect from?
right lymphatic duct drainage
29
Where do right side trunks drain in venous system?
-right jugular, right subclavian, right bronchiomediastinal -then into internal jugular and subclavian veins
30
Left Side Trunks
-all 5 trunks
31
Lymphoid Cells
several types in the lymphatic and circulatory system
32
macrophages
-monocytes that have left blood -engulf foreign substances -may present antigens to other cells -phagocytosis
33
Special Epithelial (nurse) cells
secretory cells in the thymus (thymic hormones)
34
dendritic cells
internalize antigens and present them to lymphocytes
35
Lymphocytes
-most abundant lymphoid cells -3 types that search for harmful antigens
36
T-lymphocytes (T-cells)
virally infected cells and cancer cells
37
B-lymphocytes (B-cells)
produce antibodies against bacteria
38
Natural Killer (NK cells)
cancer cells
39
Primary Lymphatic Organs
bone marrow and thymus
40
Secondary Lymphatic Organs
lymph nodes, spleen
41
Thymus
-located in mediastinum between sternum and aorta -site of T-lymphocyte differentiation and maturation
42
Cortex
-immature t cells migrate from red bone marrow to the cortex of the thymus where they begin to mature -houses immature t-lymphocytes, nurse cells, macrophages
43
Medulla
contains mature t-lymphocytes and epithelial cells
44
In adulthood...
t lymphocytes can only be produced by cell division and not by maturation of new cells in the thymus
45
Thymus Mass
gets smaller by ~10x as you age
46
Capsule
47
Trabeculae
48
Lobules
49
Lymph Nodes
-bean shaped parts alone lymphatic vessels
50
Trabeculae
-capsular extensions that divide the node into compartments
51
Stroma
52
Parenchyma
53
Paracortex
54
Medulla
55
Spleen
-located in left upper quadrant of the abdomen -below diaphragm -beside ribs 9-11 -largest lymphoid organ in the body
56
Hilum
where splenic artery and vein enter
57
Capsule
surrounds spleen and sends trabeculae extensions into the organ
58
Trabecular Vessels
-branches of splenic arteries and veins -extend within trabeculae
59
Red Pulp
-Surrounds each cluster of white pulp -blood filled venous sinuses
60
White Pulp
-most lymphocytes and macrophages arranged around central arteries
61
Immune Response
B and T cells
62
Splenic (Billroth's) Cord
-rbc, macrophages, lymphocytes, plasma cells, granulocytes
63
Functions within Red Pulp of spleen
1. remove defective blood cells and platelets via macrophages 2. store 1/3 of bodys supply of platelets 3. produce blood cells during fetal life
64
Functions of the Spleen
-initiate immune response -reservoir for erythrocytes and platelets -phagocytize old RBCs and platelets -phagocytize bacteria and other foreign material