Chapter 21- Alterations of Hormonal Regulation Flashcards

1
Q

Which of the following laboratory values would be expected in an individual with SIADH?

a. Serum sodium = 150 mEq/L and urine hypoosmolality
b. Serum potassium = 5 mEq/L and serum hypoosmolality
c. a. Serum sodium = 120 mEq/L and serum hypoosmolality
d. Serum potassium = 3 mEq/L and serum hypoosmolality

A

c. a. Serum sodium = 120 mEq/L and serum hypoosmolality

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2
Q

Hypopituitarism in an adult male likely includes:

a. decreased libido
b. connective tissue increases
c. visual field impairments
d. altered neuromuscular function

A

a. decreased libido

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3
Q

Excessive secretion of GH in an adult may cause:

a. diabetes mellitus type 2
b. diabetes insipidus
c. hypoglycemia
d. decreased metabolic rate

A

a. diabetes mellitus type 2

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4
Q

A characteristic shared by both diabetes mellitus and diabetes insipidus is:

a. elevated blood and urine glucose levels
b. the inability to produce ADH
c. the inability to produce insulin
d. polyuria
e. elevated blood urine and ketone body levels

A

d. polyuria

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5
Q

The manifestations of hyperthyroidism include all of the following except:

a. diarrhea
b. constipation
c. heat intolerance
d. weight loss
e. wakefulness

A

b. constipation

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6
Q

Hypothyroidism in adults is:

a. myxedema
b. Addison disease
c. Cushings disease
d. Graves disease
e. cretinism

A

a. myxedema

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7
Q

Graves disease is:

a. hyperthyroidism
b. associated with autoimmunity
c. manifested by opthalmopathy
d. All of the above are correct

A

d. All of the above are correct

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8
Q

Inadequate levels of thyroid hormones at birth may cause:

a. mental retardation
b. immediate death
c. thyroid crisis
d. myxedema
e. dwarfism

A

a. mental retardation and

e. dwarfism

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9
Q

Hyperparathyroidism causes which of the following?

a. Increased osteoclastic activity
b. Decreased plasma calcium
c. Increased phosphorus absorption from the gastrointestinal tract
d. Hypocalcemia

A

a. Increased osteoclastic activity

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10
Q

Manifestations of hypocalcemia include:

a. myopathy
b. lethargy
c. hypertension
d. tetany
e. bone cysts

A

d. tetany

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11
Q

What is the most common cause of acromegaly?

a. Anterior pituitary adenoma
b. Overproduction of ACTH
c. Overproduction of TSH
d. Pituitary atrophy

A

a. Anterior pituitary adenoma

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12
Q

If a 19-year-old woman had shortness of breath, weight loss, excessive sweating, exopthalmos, and irritability, which hormone would you expect to find elevated in her serum?

a. Cortisol
b. Thyroxine
c. ACTH
d. 17-Ketosteroid

A

b. Thyroxine

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13
Q

A 24-year-old woman with a history of taking sulfonylurea agents is found in a stuporous state. She is pale and has cold, clammy skin. What is the likely etiology of her condition?

a. Hyperglycemia
b. Insulin shock/hypoglycemia
c. Renal failure
d. Peripheral neuropathy

A

b. Insulin shock/hypoglycemia

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14
Q

A 10-year-old boy came into the emergency department dehydrated with metabolic acidosis, hyperkalemia, elevated ketones, and a blood glucose level of 800 mg/dl. The most probable disease in this child is:

a. cretinism
b. type 1 diabetes mellitus
c. type 2 diabetes mellitus
d. impaired glucose tolerance (IGT)
e. gestational diabetes mellitus (GDM)

A

b. type 1 diabetes mellitus

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15
Q

Your neighbor has not been previously diabetic but has gained 80 pounds during the past year and is able to produce some insulin. Her fasting blood sugar is always elevated. She is being treated with oral insulin-stimulating drugs. This is likely:

a. diabetes insipidus
b. type 1 diabetes mellitus
c. type 2 diabetes mellitus
d. IGT
e. GDM

A

c. type 2 diabetes mellitus

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16
Q

Panhypopituitarism in children causes:

a. excessive ACTH secretion
b. increased libido
c. dwarfism
d. giantism

A

c. dwarfism

17
Q

Hormonal alterations can be caused by:

a. inadequate synthesis of cAMP
b. increased numbers of intracellular receptors for lipid-soluble hormones
d. presence of antibodies against specific receptors

A

d. presence of antibodies against specific receptors

18
Q

Chronic renal failure causes:

a. dehydration
b. hypercalcemia
c. secondary hyperparathyroidism
d. primary hypepararthyroidism

A

c. secondary hyperparathyroidism

19
Q

The end result of hyperthyroidism is:

a. the presence of a goiter
b. Graves disease
c. overstimulation of the basal metabolic rate
d. depression of metabolism

A

c. overstimulation of the basal metabolic rate

20
Q

If an individual is heterogeneous for HLA-DR3 and HLA-DR4, the risk is far greater for:

a. excess insulin
b. type 1 diabetes mellitus
c. type 2 diabetes mellitus
d. All of the above are correct, plus diabetes insipidus

A

b. type 1 diabetes mellitus

21
Q

Intragenic hyperadrenalism leads to primary adrenal insufficiency if treatment is stopped suddenly because of:

a. destruction of the adrenal cortex by steroid treatment
b. destruction of the adrenal medulla by steroid treatment
c. pituitary gland atrophy
d. adrenal gland atrophy

A

d. adrenal gland atrophy

22
Q

Which electrolyte change occurs in Addison disease?

a. Hypokalemia
b. Hypernatremia
c. Hyperkalemia
d. Hypocalemia

A

c. Hyperkalemia

23
Q

A benign tumor of the adrenal glands that causes the hypersecretion of aldosterone is:

a. Addison disease
b. a pheochromocytoma
c. Cushing disease
d. Cushing syndrome
e. Conn disease

A

e. Conn disease

24
Q

Match the hypersecretion with the consequence

Hypersecretion of aldosterone

a. decreased cardiac output
b. hyperglycemia and/or osteoporosis
c. basal metabolic rate increases
d. hypernatremia
e. hyponatremia

A

d. hypernatremia

25
Q

Match the hypersecretion with the consequence

Hypersecretion of glucocrtoids

a. decreased cardiac output
b. hyperglycemia and/or osteoporosis
c. basal metabolic rate increases
d. hypernatremia
e. hyponatremia

A

b. hyperglycemia and/or osteoporosis