Chapter 20/21 Flashcards

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0
Q

Once interstitial fluids enters the lymphatic vessels it is called ____.

A

Lymph

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1
Q

____ ___ Elaborate networks of drainage vessels that collect the excess protein containing interstitial fluid and return it to the bloodstream.

A

Lymphatic vessels or lymphatics

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2
Q

The transport of lymph begins in microscopic blind ended _______ ____. They are widespread but they are absent from bones, teeth, bone marrow and the entire central nervous system.

A

Lymphatic capillaries

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3
Q

A special set of lymphatic capillaries called ____ transports absorbed fat from the small intestine to the bloodstream.

A

Lacteals

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4
Q

Fatty lymph called ___ drains from the finger like villi of the intestinal mucosa

A

Chyle

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5
Q

The ___ ___ ___ drains lymph from the right upper limb and the right side of the head and thorax.

A

Right lymphatic duct

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6
Q

The much larger __ ___ receives lymph from the rest of the body.

A

Thoracic duct

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7
Q

The __ ___ that collects lymph from the two large lumber trunks that drain the lower limbs and from the intestinal trunk that drains digestive organs.

A

Cisterna Chuli

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8
Q

___ the main warriors of the immune system arise in red bone marrow

A

Lymphocytes

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9
Q

Phagocytize foreign substances and help activate T cells are _____

A

Macrophages

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10
Q

Spiny looking cells with functions similar to macrophages are ___

A

Dendritic cells

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11
Q

Fibroblast like cells that produce a stroma or network that supports other cell type in lymphoid organs are ____ ___

A

Reticular cells

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12
Q

___ - macrophages destroy microorganism and debris

A

Filtration

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13
Q

The principal lymphoid organs in the body are the ____ ___ which cluster along the lymphatic vessels of the body.

A

Lymph node

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14
Q

The soft blood rich _____ is about the size of a fist and is the largest lymphoid organ

A

Spleen

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15
Q

The ____ form a ring of lymphoid tissue around the entrance to the pharynx where they appear as a swellings of the mucosa

A

Tonsils

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16
Q

___ ___ ___ which “police” the body any in blood and lymph are a unique group of defensive cells that can lose and kill cancer cells and virus infected body cells before the adaptive immune system is activated

A

Natural killer cells

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17
Q

___ ___ is triggered whenever body tissues are injured by physical trauma intense heat irritating chemicals or infected by viruses fungi or bacteria

A

Inflammatory response

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18
Q

Oversee humoral immunity

A

B cells

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19
Q

__ ___ are non antibody producing lymphocytes that constitute the cellular arm of adaptive immunity

A

T lymphocytes T cell

20
Q

____ ___ ____ engulf antigens and then present fragments of them like signal flags on their own surfaces where T cells can recognize them.

A

Antigen presenting cells (APC)

21
Q

____ are substances that can mobilize the adaptive defenses and provoke an immune responses.

A

Antigen

22
Q

____ ____ ____ is more like an elite fighting force equipped with high tech weapons to attack particular foreign substances.

A

Adaptive defense system

23
Q

The ___ ___ is a functional system rather than an organ system in an anatomical sense.

A

Immune system

24
Q

___ harmful or disease causing microorganisms

A

Pathogens

25
Q

The ___ ___ ___ like a lowly foot soldier is always prepared responding within minutes to protect the body from all foreign substances.

A

Innate (nonspecific) defense system

26
Q

___ are complement proteins or antibodies that provide “handles” to which phagocyte receptors can bind.

A

Opsonins

27
Q

Any pathogen can be coated with opsonins a process called _____ (to make tasty) which greatly accelerate phagocytosis of that pathogen.

A

Opsonization

28
Q

The redness and heat of an inflamed region are both due to local ____ (congestion with blood) that occurs when local arterioles dilate.

A

Hyperemia

29
Q

The four cardinal signs of short term or acute inflammation are

A

Redness, heat, swelling, and pain

30
Q

Infected cells can do little to save themselves but some can secrete small proteins called ___ to help protect cells that have not yet been infected

A

Interferons

31
Q

The term ___ ___ refers to a group of at least 20 plasma proteins that normally circulate in the blood in an inactive state.

A

Complement system

32
Q

___ the increase in white blood cells is characteristic of inflammation.

A

Leukocytosis

33
Q

Continued chemical signaling prompts the neutrophils to flatten and squeeze between the endothelial cells of the capillary walls a process called ___

A

Diapedesis

34
Q

Most cells of the clone differentiate into ___ ___ the antibody secreting effector cells of the humoral response.

A

Plasma cells

35
Q

Clone cells that do not become plasma cells become long lived __ ___. They can mount an almost immediate humoral response if they encounter the same antigen again in the future

A

Memory cells

36
Q

The troublesome small molecule is called a ___ or incomplete antigen.

A

Hapten

37
Q

Only certain parts of the antigen called ___ _____ are immunogenic.

A

Antigenic determinants

38
Q

____ ___ is an important component of the immune system because it houses and provides a proliferation site for lymphocytes & furnishes an ideal surveillance vantage point for lymphocytes & macrophages

A

Lymphoid tissue

39
Q

___ ___ ___ the body’s built in specific defensive system that stalks and eliminates with nearly equal precision almost any type of pathogen that intruded into the body.

A

Adaptive immune system

40
Q

___ ____ is provided by antibodies present in the body’s humors or fluids (blood, lymph)

A

Humoral immunity

41
Q

___ or abnormally high body temperature is a systemic response to invading microorganisms

A

Fever

42
Q

When leukocyte sand macrophages are exposed to foreign substances in the body they release chemicals called ___. They act on the body’s thermostat a cluster of neurons in the hypothalamus raising the body temp above normal.

A

Pyrogens

43
Q

The ___ ____ involves antibodies water soluble protein molecules that the adaptive immune system produces to fight off foreign invaders.

A

Classical pathway

44
Q

The ___ ___ involves lectins water soluble protein molecules that the innate immune system produces to recognize foreign invaders

A

Lectin pathway

45
Q

The ___ ___ is triggered when spontaneously activated C3 and other complement factors interact on the surface of microorganisms

A

Alternative pathway

46
Q

Cell lysis begins when C3b binds to the target cells surface and triggers the insertion of a group of complement proteins called ____ into the cells membrane. (Form and stabilizes a hole in the membrane that allows a massive influx of water losing the target cell)

A

MAC (membrane attack complex)

47
Q

This army of identical cells all descended from the same ancestor cell is called ____

A

Clone

48
Q

Most members of the clone become ___ ____ the cells that actually do the work of fighting infection.

A

Effector cells