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Fitzpatrick Tables > Chapter 186 - Systemic and Topical Antibiotics > Flashcards

Chapter 186 - Systemic and Topical Antibiotics Flashcards

1
Q

TABLE 186-3
Contraindications and Precautions of Penicillin Therapy

Fill in the blanks

Known _____ to penicillin

A

Known hypersensitivity to penicillin

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2
Q

TABLE 186-3
Contraindications and Precautions of Penicillin Therapy

Fill in the blanks

_____ penicillin levels with probenecid and disulfiram

A

Increased penicillin levels with probenecid and disulfiram

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3
Q

TABLE 186-3
Contraindications and Precautions of Penicillin Therapy

Fill in the blanks

_____ effect of methotrexate and warfarin

A

Enhanced effect of methotrexate and warfarin

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4
Q

TABLE 186-3
Contraindications and Precautions of Penicillin Therapy

Fill in the blanks

Use with caution in patients with _____ impairment

A

Use with caution in patients with renal impairment

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5
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Penicillins

A

B

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6
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Cephalosporins

A

B

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7
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Tetracyclines

A

D

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8
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Fluoroquinolones

A

C

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9
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Trimethoprim-sulfamethoxazole

A

D

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10
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Lincosamides (clindamycin)

A

B

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11
Q

TABLE 186-5
Adverse Effects

PREGNANCY CLASS
Macrolides

A

B/C

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12
Q

TABLE 186-5
Adverse Effects

COMMON ADVERSE EFFECTS
Skin and nail hyperpigmentation

A

Minocycline

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13
Q

TABLE 186-5
Adverse Effects

COMMON ADVERSE EFFECTS
Dysgeusia

A

Clarithromycin

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14
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Neurotoxicity (high dose)

A

Penicillins

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15
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Pulmonary infiltrate with eosinophilia (PIE)

A

Penicillins

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16
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Serum sickness-like reaction (2)

A

Cefaclor
Cefprozil

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17
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Pseudocholelithiasis

A

Ceftriaxone

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18
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Photosensitivity

A

Doxycycline

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19
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Vestibular toxicity

A

Minocycline

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20
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Blood dyscrasias (long term use)

A

Tetracyclines

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21
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Tendon rupture, arthropathy (in the immature)

A

Fluoroquinolones

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22
Q

TABLE 186-5
Adverse Effects

UNCOMMON ADVERSE EFFECTS
Elevated hepatic transaminases (reversible)

A

Lincosamides (clindamycin)

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23
Q

TABLE 186-7
Contraindications and Precautions of
Cephalosporin Therapy

Fill in the blanks

Known _____ to cephalosporin or penicillin

A

Known hypersensitivity to cephalosporin or penicillin

24
Q

TABLE 186-7
Contraindications and Precautions of
Cephalosporin Therapy

Fill in the blanks

_____ absorption of cefdinir with antacids and iron salts

A

Reduced absorption of cefdinir with antacids and iron salts

25
Q

TABLE 186-7
Contraindications and Precautions of
Cephalosporin Therapy

Fill in the blanks

_____ cyclosporine levels with ceftriaxone and ceftazidime

A

Increased cyclosporine levels with ceftriaxone and ceftazidime

26
Q

TABLE 186-7
Contraindications and Precautions of
Cephalosporin Therapy

Fill in the blanks

_____ effect of warfarin with cefotetan, cefamandole, cefoperazone, cefixime, and cefaclor

A

Altered effect of warfarin with cefotetan, cefamandole, cefoperazone, cefixime, and cefaclor

27
Q

TABLE 186-7
Contraindications and Precautions of
Cephalosporin Therapy

Fill in the blanks

Impaired _____ excretion of most cephalosporins with probenecid

A

Impaired renal excretion of most cephalosporins with probenecid

28
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

Patients with _____ failure (impaired excretion and antianabolic properties)

A

Patients with renal failure (impaired excretion and antianabolic properties)

29
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

Photosensitivity (_____)

A

Photosensitivity (doxycycline)

30
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

Nursing, pregnancy, and childhood years (_____ years of age)

A

Nursing, pregnancy, and childhood years (<9 years of age)

31
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

_____ absorption by calcium, magnesium, aluminum (other cations), iron, sodium bicarbonate, and cimetidine

A

Impaired absorption by calcium, magnesium, aluminum (other cations), iron, sodium bicarbonate, and cimetidine

32
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

_____ metabolism of doxycycline with the use of phenytoin, carbamazepine, barbiturates, and alcohol

A

Increased metabolism of doxycycline with the use of phenytoin, carbamazepine, barbiturates, and alcohol

33
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

_____ insulin requirements in diabetic patients

A

Reduced insulin requirements in diabetic patients

34
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

_____ serum levels of digoxin, lithium, and warfarin

A

Increased serum levels of digoxin, lithium, and warfarin

35
Q

TABLE 186-9
Contraindications and Precautions of
Tetracycline Therapy

Fill in the blanks

Methoxyflurane anesthesia (_____ failure)

A

Methoxyflurane anesthesia (renal failure)

36
Q

TABLE 186-11
Contraindications and Precautions of
Clindamycin Therapy

Fill in the blanks

_____ of neuromuscular blockade with tubocurarine and pancuronium

A

Enhancement of neuromuscular blockade with tubocurarine and pancuronium

37
Q

TABLE 186-11
Contraindications and Precautions of
Clindamycin Therapy

Fill in the blanks

Possible _____ with erythromycin

A

Possible antagonism with erythromycin

38
Q

TABLE 186-11
Contraindications and Precautions of
Clindamycin Therapy

Give 2

A

Hepatic failure
Colitis

39
Q

TABLE 186-15
Contraindications and Precautions of
Fluoroquinolone Therapy

Fill in the blanks

_____ bioavailability with antacids (aluminum, magnesium, alum), iron, zinc, and sucralfate

A

Decreased bioavailability with antacids (aluminum, magnesium, alum), iron, zinc, and sucralfate

40
Q

TABLE 186-15
Contraindications and Precautions of
Fluoroquinolone Therapy

Fill in the blanks

Inhibited theophylline and aminophylline metabolism (_____)

A

Inhibited theophylline and aminophylline metabolism (ciprofloxacin)

41
Q

TABLE 186-15
Contraindications and Precautions of
Fluoroquinolone Therapy

Fill in the blanks

Tendon rupture (in patients with _____ disease, _____, or _____)

A

Tendon rupture (in patients with renal disease, hemodialysis, or steroid use)

42
Q

TABLE 186-15
Contraindications and Precautions of
Fluoroquinolone Therapy

Fill in the blanks

_____ seizure threshold

A

Decreased seizure threshold

42
Q

TABLE 186-15
Contraindications and Precautions of
Fluoroquinolone Therapy

Fill in the blanks

_____ warfarin and cyclosporine metabolism

A

Decreased warfarin and cyclosporine metabolism

43
Q

TABLE 186-17
Contraindications and Precautions of
Trimethoprim-Sulfamethoxazole Therapy

Fill in the blanks

Severe reactions in patients with _____

A

Severe reactions in patients with HIV/AIDS

44
Q

TABLE 186-17
Contraindications and Precautions of
Trimethoprim-Sulfamethoxazole Therapy

Fill in the blanks

_____ prothrombin time in patients on warfarin

A

Prolonged prothrombin time in patients on warfarin

45
Q

TABLE 186-17
Contraindications and Precautions of
Trimethoprim-Sulfamethoxazole Therapy

Fill in the blanks

Contraindicated for patients on _____

A

Contraindicated for patients on methotrexate

46
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Clindamycin

A

B

46
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Mupirocin

A

B

47
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Retapamulin

A

B

48
Q

TABLE 186-18
Topical Antibiotics

For use in children >9 months of age only

A

Retapamulin

49
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Bacitracin

A

C

50
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Polymyxin B

A

C

51
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Neomycin

A

D

52
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Gentamicin

A

C

53
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Silver sulfadiazine

A

B

54
Q

TABLE 186-18
Topical Antibiotics

SAFETY
Fusidic acid

A

Safe to use during pregnancy

Fitzpatrick Tables (19 decks)

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