Chapter 16 - The Endocrine System Flashcards
hormones
signaling molecules secreted into the bloodstream
paracrine factors and neurotransmitters travel to , hormones travel to
near cells only, near and far cells
the endocrine system is made of
glands, tissues, hormone-secreting cells
endocrine glands
organs that secrete hormones
speed of the endocrine system
slow response and a long, persistent effect
adaption of endocrine system to stimulus
very slow
area of effect of the endocrine system
variable, generous or specific
exocrine glands function
secrete substances through ducts
duct
tube that delivers secretion to an epithelial surface or the mucosa of the digestive tract
does the exocrine gland do intracellular or extracellular communication
extracellular
products of the exocrine gland
sweat, saliva, digestive enzymes, mucus
endocrine glands produce
hormones that cause intracellular changes in target cells
endocrine glands are for intracellular or extracellular communication
intracellular
endocrine glands are penetrated by
capillaries into which hormones are secreted
hormones are/are not secreted at a continuous rate
are not
types of rhythmic secretions
circadian rhythm, monthly cycle
example of a circadian rhythm
melatonin
types of stimuli secretions
neural, hormonal, humoral
neural stimuli secretion process
nerve signals endocrine system to secrete hormones
example of a neural stimulated secretion
sympathetic stimulus of adrenal medulla
hormonal stimulating secretion process
hormones stimulate another source’s secretion
example of hormonal stimulated secretion
hypothalamus stimulates the anterior pituitary gland
humoral stimulating secretion process
blood levels of some substance stimulates hormone secretion
example of humoral secretion stimulation
blood glucose
hormone classes
steroid, monoamine, peptides
steroids are derived from
cholesterol
monoamines are derived from
an amino acid
peptides are derived from
multiple amino acids
monoamines and peptides travel through
blood plasma
monoamines and peptides are hydrophobic/hydrophilic
hydrophilic
steroids travel by
binding to transport proteins that travel through the blood streams
steroids are hydrophobic/hydrophilic
hydrophobic
example of a transport protein to which steroid
albumin
hormone receptors are specific/general
specific, only stimulate the cells with the specific receptors for that hormone
how are hormone receptors sensitive
more receptors on the cell make a cell more sensitive to the effects of the hormone
long term exposure to a hormone causes
less expression / more cell sensitivity
types of hormones receptors
membrane receptors and intracellular receptors
what type of hormone(s) bind to membrane receptors
peptides and monoamines
what type of hormone(s) bind to intracellular receptors
steroids
signal amplification
binding of a hormone to a receptor leads to activation of second messengers
what type of hormone(s) use a second messenger
monoamines and peptides
what type of hormone(s) directly affect gene transcription
steroids, go straight to the nucleus
synergist hormone interactions
hormones amplify effect of each other
example of synergist hormones
FSH and Testosterone to produce sperm
permissive hormone interactions
one hormone allows/enhances a cell’s response to another
example of permissive hormones
Estrogen increases the sensitivity of the uterus to progesterone
antagonistic hormone interactions
hormones have opposite effects of each other on a cell
hormone clearance
hormone effects are eventually stopped through degradation
what organs do degradation
liver and kidney
how does the liver excrete hormones
bile
how does the kidney excrete hormones
urine
metabolic clearance rate
the rate hormones are removed from blood
endocrine glands
hypothalamus, anterior pituitary, posterior pituitary
hypothalamus function
directs the pituitary gland
hypothalamus location
funnel-shaped region of the brain inferior to the thalamus
the pituitary gland is also called the
hypophysis
pituitary gland function
master gland that controls the endocrine system
pituitary gland location
attached to the hypothalamus by the infundibular stalk
anterior pituitary gland is also called
adenohypophysis
the anterior pituitary gland makes up how much of the overall gland
3/4
the anterior pituitary gland is made up of what kind of tissue
glandular tissue
how does the anterior pituitary gland communicate with the hypothalamus?
through the hypophyseal portal system
the posterior pituitary gland is also called
neurohypophysis
the posterior pituitary gland makes up how much of the overall gland
1/4
what type of tissue is the posterior pituitary gland made out of?
nervous tissue
how does the posterior pituitary gland communicate with the hypothalamus
axon tracts
what type of hormones are reproductive
gonadotropin
types of gonadotropins
FSH and LH
FSH stands for
follicle-stimulating hormone
LH stands for
luteinizing hormone
Effects of FSH on a female
stimulates ovarian follicle development
effects of FSH on a male
stimulate sperm function
Thyroid Stimulating Hormone (TSH)
stimulates thyroid to secrete thyroid hormone
Adrenocorticotropic Hormone (ACTH)
stimulates adrenal cortex secrete glucocorticoids
what are glucocorticoids
anti stress hormoness
example of a glucocorticoids
cortisol
Prolactin (PRL)
stimulates memory gland to make milk
Growth Hormone (GH)
cause growth in tissues and organs by stimulating mitosis and cellular differentiation
Anterior Pituitary Regulating Hormones
Thyrotropin Releasing Hormone, Corticotrophin Releasing Hormone, Gonadotropin Releasing Hormone, Growth Hormone Releasing Hormone, Prolactin Inhibiting hormone, Somatostatin
Thyrotropin Releasing Hormone releases
TSH and PRL
Corticotrophin Releasing hormone releases
ACTH
Gonadotropin Releasing Hormone releases
FSH and LH
Somatostatin function
inhibits the release of growth hormone
nickname for oxytocin
the love/attachment hormone
posterior pituitary hormone
oxytocin, antidiuretic
when is oxytocin released
sexual arousal, childbirth, when with partner/children/pet
antidiuretic function
increases water retention and decreases urine volume
other name for antidiuretic and why
vasopressin because it constricts blood vessels
negative feedback loops in hormones
hormone secretion decreases as effect increases
hypothalamus and anterior pituitary gland feedback loops
hormone levels are reduced when target organ hormone levels rise
How does ADH function in a negative feedback loop?
osmoreceptors in the hypothalamus cause ADH release if blood osmolarity is high
what hormone functions in a positive feedback loop
oxytocin release in childbirth
what triggers the release of oxytocin
specific neural signals