Chapter 16 - Gastric Fluid Flashcards

1
Q

Produces gastrin

A

Specialized G cells

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2
Q

Produces HCl and intrinsic factor

A

Parietal cells

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3
Q

Intrinsic factor is needed for the absorption of ____

A

Vit B12

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4
Q

Produces pepsinogen

A

Chief cells

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5
Q

Converts pepsinogen to pepsin

A

HCl

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6
Q

Mucus-producing cells that cover the inside of the stomach

A

Foveolar cells

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7
Q

Dse causing the stomach to have no acid due to the presence of anti-parietal cell Ab or anti-Intrinsic factor Ab

A

Pernicious anemia

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8
Q

Dse causing too much acid in stomach due to non-beta islet cell adenoma of the pancreas

A

Zollinger-Ellison syndrome

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9
Q

Which of the ff causes hyperchlorhydria

A. Pernicious anemia
B. Zollinger-Ellison syndrome

A

B

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10
Q

Method of collection for gastric fluid spx

A

Gastric aspiration

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11
Q

Identify the gastric tubes described:

  1. Passed through nose
  2. Passed through mouth
  3. For evacuating gastric contents and stilling an irrigant (via mouth)
  4. For aspirating large amt of gastric contents quickly (via mouth)
A
  1. Levine
  2. Rehfuss
  3. Lavacuator tube
  4. Ewald’s tube, Edlich tube
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12
Q

Total gastric secretion during unstimulated, fasting state

A

Basal acid output (BAO)

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13
Q

Regarding BAO, routine duration of collection:

A

1 hr collection

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14
Q

Regarding BAO, duration of collection for insulin hypoglycemia test

A

2 hr collection

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15
Q

Regarding BAO 1 hr collection, it consists of ____ spx but a single 1-hr

A

Four 15-minute spx

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16
Q

Total gastric secretion after gastric stimulation

A

Maximum acid output (MAO)

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17
Q

Duration of collection for MAO

A

1 hr and 2 hr collection

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18
Q

Duration of collection for MAO when pentagastrin and histamine are used

A

1 hr collection

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19
Q

Duration of collection for MAO for insulin hypoglycemia test and when histalog is used

A

2 hr collection

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20
Q

Identify the ff test meal gastric stimulants:

  1. Bread, weak tea or water
  2. Oatmeal
  3. Biscuit
  4. Egg albumin, H2O, methylene blue
  5. Beef steak and mashed potato
A
  1. Ewald’s
  2. Boa’s
  3. Dock’s
  4. Heckman’s
  5. Riegel’s
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21
Q

Most preferred chemical stimulant

A

Pentagastrin

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22
Q

Chemical stimulant used to assess vagotomy procedure

A

Insulin

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23
Q

Enumerate the 4 chemical stimulants

A

Pentagastrin, insulin, histamine, histalog

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24
Q

Aka fictitious feeding

A

Sham feeding

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25
What food is given in sham feeding?
Sandwich
26
In pernicious anemia, what are the expected BAO, MAO and BAO/MAO ratio?
0
27
Normal BAO, MAO and BAO/MAO ratio
2.5 mEq/hr ; 25.0 mEq/hr ; 10%
28
Which is higher in cases of duodenal cancer, BAO or MAO?
MAO (30.0 mEq/hr) -BAO is 5.0
29
Which is higher in cases of Zollinger-Ellison syndrome, BAO or MAO?
MAO (25.0 mEq/hr) -BAO is 18.0
30
Which of the ff have the highest BAO/MAO ratio? A. Normal B. Pernicious anemia C. Duodenal ulcer D. Zollinger-Ellison syndrome
D (72%)
31
Normal gastric fluid appearance
Pale gray w/ mucus
32
Color of gastric fluid with large amt of bile
Yellow-green
33
Color of gastric fluid with small amt of fresh blood
Red
34
Color of gastric fluid with large amt of blood
Coffee ground
35
Normal volume of gastric fluid (fasting spx)
20-50 mL
36
Abnormal gastric fluid fasting spx volume
>50 mL
37
After Ewald’s test meal, gastric fluid volume is expected to be:
20-60 mL up to 120 mL
38
After alcohol test meal or histamine stimulation, gastric fluid volume is expected to be?
45-150 mL
39
Normal free HCl
Euchlorhydria
40
Increased free HCl
Hyperchlorhydria
41
Gastric fluid pH >3.5 but falls after gastric stimulation (decreased free HCl)
Hypochlorhydria
42
Gastric fluid pH >3.5 and does not fall even after gastric stimulation (absence of free HCl)
Anachlorhydria
43
Failure to produce a pH <6.0 following gastric stimulation
Anacidity
44
Dse assoc w/ hyperchlorhydria
Zollinger-Ellison dse, peptic ulcer
45
Dse assoc w/ hyporchlorhydria
Carcinoma of the stomach
46
Anachlorhydria is assoc w/ what dse
Pernicious anemia
47
Anacidity is assoc w/ what dse
Pernicious anemia
48
Diagnex tubeless test aka
Diagnex blue test
49
Spx for diagnex tubeless test
Urine
50
Stain used for diagnex tubeless test
Azure-A
51
regarding diagnex tubeless test: The amt of dye excreted in urine is an indicator of _____
Gastric HCl secretory activity
52
Positive result for dimethylaminoazobenzol, a qualitative test for free HCl
Cherry red
53
Lactic acid is indicative of ___
Advanced gastric cancer / gastric stagnation
54
3 tests and their endpoint color/s for lactic acid
Modified Uffelmann’s, Strauss, Kelling All of them have yellow endpoint
55
Positive result for Gunzberg test
Purple
56
Positive result for Boas
Rose red
57
What does dimethylaminobenzol, Gunzberg and Boas test?
Qualitative tests for free HCl
58
Titrant/s used for quanti test for gastric acidity using free HCl, total acidity and combined HCl (bound to proteins)
All uses sodium hydroxide as titrant
59
pH indicator/s used for quanti test for gastric acidity using free HCl, total acidity and combined HCl (bound to proteins)
Free HCl uses Topfer’s rft or dimethylaminoazobenzol Total acidity uses phenolphthalein Combined HCl uses sodium alizarin
60
Endpoint color/s for quanti test for gastric acidity using free HCl, total acidity and combined HCl (bound to proteins)
Free HCl - canary yellow Total acidity - faint pink Combined HCl - violet