Chapter 14 Flashcards

1
Q

‘Particulate’ hypothesis

A

model in which parents pass down heritable units that retain separate identities in offspring
o Genes can be shuffled and passed along

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2
Q

character

A

a heritable feature that varies among individuals

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3
Q

trait

A

each variant for a character

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4
Q

true-breeding

A

varieties that, over many generations of self-pollination, produce the same variety of parent plant (same phenotype)

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5
Q

hybridization

A

the crossing of two true-breeding varieties

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6
Q

P generation (true-breeding)

A

the true-breeding parents

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7
Q

F1 generation (true-breeding)

A

the hybrid offspring of the P generation

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8
Q

F2 generation (true-breeding)

A

results when F1 hybrids self-pollinate

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9
Q

alleles

A

alternative versions of genes

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10
Q

law of segregation

A

2 alleles for a heritable character segregate during gamete formation and end up in different gametes

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11
Q

testcross

A

when you breed an organism of an unknown genotype with a recessive homozygote
o This will reveal the genotype of the organism

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12
Q

monohybrids

A

heterozygous for one particular character in the cross

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13
Q

monohybrid cross

A

a cross between two heterozygotes for one character

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14
Q

dihybrids

A

individuals heterozygous for 2 characters in a cross

o Ex: YyRr

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15
Q

dihybrid cross

A

a cross between F1 dihybrids

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16
Q

law of independent assortment

A

states that 2 or more genes assort independently; each pair of alleles segregates independently of each other pair of alleles during gamete formation
o This applies only to allele pairs located on different chromosomes or
o Genes very far apart on the same chromosome

17
Q

multiplication rule

A

for determining the probability that 2 or more independent events will occur together, multiply the probability of one event by the probability of the other event
o Ex: events occurring on two different chromosomes

18
Q

addition rule

A

to find the probability that any 1 of 2 or more mutually exclusive events will occur, add the individual probabilities

19
Q

complete dominance

A

when the F1 offspring looks like 1 of the two parental varieties
o Phenotypes of heterozygote and dominant homozygote are indistinguishable

20
Q

incomplete dominance

A

when neither allele is completely dominant
o F1 phenotype is somewhere between the 2 parental varieties
o Ex: when R and W flowers produce pink

21
Q

codominance

A

when two alleles each affect the phenotype in separate, indistinguishable ways
o Both phenotypes are exhibited by heterozygotes since both molecules are present
o Ex: RR & WW combine to make RW (roan)

22
Q

Tay-Sachs disease

A

inherited disorder in which afflicted has brain cells which cannot metabolize certain lipids
o Lipid accumulation results in blindness, seizures, poor motor performance
o Due to incomplete dominance, but codominance at the molecular level

23
Q

pleitropy

A

genes which have multiple phenotypic effects

o Responsible for hereditary diseases such as cystic fibrosis and sickle-cell anemia

24
Q

epistasis

A

when the phenotypic expression of a gene at a locus alters that of a gene at a second locus

25
quantitative characteristics
characters that are not one of two discrete characters, but vary in populations along a continuum o Usually indicates polygenic inheritance o Ex: skin color and height
26
polygenic inheritance
an additive effect of 2 or more genes on a single phenotypic character
27
multifactorial characteristics
when many factors, both genetic and environmental, influence phenotype
28
pedigree
family tree describing the traits of parents and children across generations
29
cystic fibrosis
common lethal genetic disease o Results in abnormally high concen. of extracellular chloride, producing mucus o Results from two recessive alleles
30
sickle-cell disease
caused by substitution of single amino acid in hemoglobin protein of red blood cells o 2 sickle-cell alleles required for full-blown manifestation (codominance) o One copy of sickle-cell allele can have issues as well, protects against malaria
31
huntington's disease
caused by lethal dominant allele, deterioration of nervous system
32
amniocentesis
test during the 14th-16th week of pregnancy o Can determine if fetus has Tay-Sach’s disease o Extract amniotic fluid
33
chorionic villus sampling (CVS)
when physician gets tissue from placenta | o Advantage- rapid cell proliferation