Chapter 12 Flashcards
-Found in the blood an migrate out of the blood and into the tissues when stimulated
Neutrophils
-React early in the inflammatory response
Neutrophils
are transformed into macrophages after they migrate out of the bloodstream and into the tissues.
Monocytes
live in a certain tissue
Histiocytes
microglial cells are?
in the CNS
Lung macrophages are?
Alveolar
cells in the liver are?
Kupffer
What cells are in the skin?
dendritic
what is the chemical trail called that leads to the injury?
chemotaxis
single molecules found on microbial surfaces recognized by phagocytes and other defensive cells are?
pathogen-associated molecular patterns (PAMPS)
What are molecules shared by many organisms, but not present in mammals?
PAMPS
What are PRR’s ?
pattern recognition receptors
What are found on phagocytes, dendritic cells, endothelial cells, and lymphocytes?
PRR’s
What recognizes and bind PAMPs
PRR’s
What is it called when phagocytes use pattern recognition to identify and stick to foreign cells?
attachment.
Once the phagocyte had made contact with its prey it extends pseudopods that enclose the cells or particles in a pocket and internalize them in a vacuole called a phagosome. It secretes more cytokines to further amplify the innate response.
Engulfment.
in a short time lysosomes migrate to the scene of the phagosome and fuse with it to form a phagolysosome.
Phagolysosome formation
redness caused by increased circulation and vasodilation in the injured tissue is?
rubor
heat or warmth caused by the heat given off by the increased flow of blood is?
calor
swelling caused by fluid escaping into the tissues is?
tumor