chapter 11/12 neuroanamony Flashcards
The nervous system
The nervous system (in particular cerebral cortex) is that body system responsible for voluntary activity
The nervous system is the source of
The nervous system is the source of our (unique?) communication ability
Human brains are heavier and more developed than primates
Note, laryngological differences also
Cerebrum
largest mass of brain tissue
Cerebral hemispheres
Left and right hemispheres connected by corpus callosum
CNS (aka neuraxis)
Brain and spinal cord
Housed in bone
PNS
12 pairs cranial nerves + 31 pairs spinal nerves + sensory receptors
Mostly outside of bone
Autonomic nervous system
regulates bodily functions & activity of specific organs (not consciously controlled)
controls vital functions (e.g., respiration and digestion)
Somatic nervous system
: voluntary control of body movements and reception of external stimuli
Somatic: pertaining to the body
Conscious/voluntary control of skeletal mm
2 components of Autonomic Nervous System
Sympathetic
Parasympathetic
Parasympathetic
NS slows and relaxes (“rest and digest”) [damping response following excitation
sympathetic
NS stimulates organs and systems (“fight or flight”) [excitatory response to stimulation
2 components Somatic Nervous System
motor and sensory
motor
neural impulses sent from brain via brainstem and spinal cord by means of tracts (pathways) to periphery [efferent]
sensory
monitoring of information regarding body’s status and the environment sent to the brain [afferent]
Sensation
Sensation begins with the reception of a stimulus by a receptor cell and continues with the passage of information onto the brain
Mechanoreceptors
physical distortion receptors
Chemoreceptors
specific molecules
E.g., Olfaction, gustation
Photoreceptors
light
Thermoreceptors
Temperature
Specific sensory classes
somatic and special
somatic
related to pain, thermal stimulation, mechanical stimulation.
special
involved in changing a stimulus to another form of energy (e.g., gustation, olfaction, vision, hearing)
All structures are constructed from
All structures are constructed from neurons and glia
neurons
Neurons transmit information
glial cells
Glial cells are involved in support functions
Neurons consist
Neurons consist of a cell body/soma, axon and dendrite
Neurons have 2 responses (excitation/inhibition)
A nerve cell in the PNS
ganglion
Neuronal anatomy
Axon: process that transmits info from the soma
Hillock
Myelin sheath [insulation]
Nodes of Ranvier
Terminal end boutons
Neurotransmitter
Dendrite: process that transmits info to the soma
Synaptic cleft: region between 2 communicating neurons
Axons are covered with
myelin sheaths
Schwann
cells make PNS myelin
Oligodendrocytes
make CNS myelin
Myelin
speeds up neural conduction
Terminal end boutons contain
Terminal end boutons contain synaptic vesicles in which a chemical (neurotransmitter) is held
The neurotransmitter is released into the synaptic cleft and bind to receptor sites on the adjacent neuron
Cell bodies
gray matter
Myelin
white matter
Interneurons:
communicate bw neurons
Motor neurons
activate mm or gland response
Glial cells
Glial cells involved in support functions
Different varieties
Astrocytes: supply nutrients
Oligodendrocytes: myelin
Schwann cells: myelin
Microglia: phagocytosis (get rid of waste)
The cerebrum is made up of 2 halves or hemispheres
left and right hemispheres
Hemispheres are grossly similar anatomically
Situated in the postero-inferior aspect of the cerebrum
lies the cerebellum (little cerebrum)
Anterior to the cerebellum
lies a thickening of the spinal cord called the brainstem
3 meningeal linings protect and support the brain structure
Dura mater
Arachnoid mater
Pia mater
Dura Mater
most superficial
most superficial, bilayered lining
Contains meningeal arteries
Arachnoid mater
intermediate
Blood vessels deep to arachnoid, in pia
Spider-like structure with cerebral spinal fluid in sub-arachnoid space
Separates superficial and deep meningeal linings
Pia Mater
deepest
Deepest layer
Major arteries and veins course through it
The meningeal linings
to hold structures in place during movement, provide support for structures
he meninges help to protect from shock
Meninges have 4 major infoldings
Falx cerebri
Falx cerebelli
Tentorium cerebelli
Falx cerebri
Dura that separates L and R hemispheres
Falx cerebelli
Dura that separates L and R cerebellar hemispheres
Tentorium cerebelli
Dura that separates cerebrum and cerebellum
Spinal cord meninges
parallel the structure and function of the cerebral meninges
Cerebrospinal fluid (CSF)
is a fluid substance traveling in sub-arachnoid space that
Cushions neural tissue
Engages in nutrient delivery
Helps with waste removal
CSF is completely replenished every 7 hours
CSF travels from lateral ventricles to 3rd and 4th ventricles to sub-arachnoid space and drains into venous system
CSF circulates around outside of brain and spinal cord
CSF is produced
produced by groups of tissue called choroid plexus
CSF is found
in various spaces throughout the cerebrum Ventricular system Lateral (right and left) 3rd 4th
what ventricles produce most CSF
Choroid plexuses of the lateral cerebral ventricles produce most CSF
Lateral ventricles
C-shaped paired structures
Lateral ventricles are connected to 3rd ventricle via interventricular foramen of Monro
3rd ventricle
unpaired cavity b/w L and R thalami and hypothalami that are connected via the inter-thalamic adhesion
4th ventricle
space b/w brainstem and cerebellum
Cerebrum
= 2 hemispheres with an outer surface or cortex that has both columnar and laminar organization
Laminar organization
cortex has 6 layers
Introduction to Brodmann Areas
Brodmann classified areas of cortex based on the dominant neuron he saw in ea.
Divides brain into 47 regions
Is the standard reference for cerebral cortex
The areas are amazingly accurate in identifying functional differences
e.g., BA 44,45 = Broca’s area
Cerebral Landmarks
Longitudinal fissure (aka superior longitudinal fissure or interhemispheric fissure)
Gyri and sulci (and fissures)
6 lobes
Frontal, parietal, occipital, temporal, limbic, insular
Lateral sulcus or Sylvian fissure
Central sulcus or Rolandic fissure
Frontal Lobe
The frontal lobe: largest of all the lobes
Involved in planning, initiation, and inhibition of movement, as well as many aspects of cognition and executive function
Boundaries: lateral & central sulci, longit. fissure
Frontal Lobe Landmarks
Anterior lateral aspect has superior, middle and inferior frontal gyri
Inferior frontal gyrus contains
the frontal operculum or Broca’s area (L)
Also, the pre-central gyrus or motor strip anterior to the central sulcus
Premotor area & Supplementary motor cortex/area
Homunculus
Organized representation of the body
Different degrees of representation
Parietal Lobe
The parietal lobe is primarily involved in the somatic sense
Boundaries: lateral & central sulci, & the parieto-occipital sulcus
Parietal Lobe Landmarks
Postcentral gyrus
Postcentral sulcus separates postcentral gyrus from the inferior and superior parietal lobules
Inferior parietal lobule
Supramarginal and angular gyrus
Parietal function
Sensory Homunculus
Organized representation of the body
Different degrees of representation
E.g., greater representation of face
Inferior parietal lobule is an association area important for integrating visual, auditory and somato-sensory information
Angular gyrus has been implicated in reading comprehension
Sensory Homunculus
Organized representation of the body
Different degrees of representation
E.g., greater representation of face
Inferior parietal lobule is an association
Inferior parietal lobule is an association area important for integrating visual, auditory and somato-sensory information
Angular gyrus has been implicated
Angular gyrus has been implicated in reading comprehension
Temporal Lobe
The temporal lobe is primarily involved in auditory processing
Also involved in receptive language processing (comprehension)
Boundary: lateral sulcus
Temporal Lobe Landmarks
Superior temporal gyrus Heschl’s gyrus Wernicke’s area Middle temporal gyrus Inferior temporal gyrus
Temporal function
ALL auditory information is projected to Heschl’s gyrus (41)
Brodmann’s area 42 and middle/inferior temporal gyri are involved in higher order auditory processing
Wernicke’s area (22) is involved in receptive language processing
Brodmann’s area 42
Brodmann’s area 42 and middle/inferior temporal gyri are involved in higher order auditory processing
Wernicke’s area (22)
is involved in receptive language processing
Occipital Lobe
The occipital lobe is primarily involved in visual processing
Boundary: parieto-occipital sulcus, longitudinal fissure
V1 (area 17)
Insular Lobe
The insula is found deep in the lateral sulcus
The insula may be involved in motor-speech processing
Limbic Lobe (“System”)
The limbic lobe has various components that are not anatomically adjacent
The limbic lobe is involved in emotion and motivation and memory
Parts of the limbic system include:
The amygdala, the parahippocampal gyrus, cingulate gyrus, the olfactory bulb/tract