Chapter 10 - Substance Use Disorders Flashcards
Prior to the DSM 5, pathological use of substances fell into these categories
substance abuse
substance dependence
Problems with the two category distinction
poor reliability of the substance abuse category
most people who meet criteria for abuse do not develop dependence
represent only one category
Proposed criteria for Substance Use
problematic pattern of use that impairs functioning 2 or more in 1 year failure to meet obligations repeat use in dangerous situations repeated relationship problems continued use despite problems from use tolerance withdrawal taken longer or in larger doses efforts to reduce/control do not work spend time trying to obtain substance other activities redued continued use despite knowing problems caused by substance strong craving
A more severe substance use disorder that is characterized by having more symptoms,tolerance and withdrawal, by using more of the substance than intended, by trying unsuccessfully to stop, by having physical or psychological problems made worse by the drug and by experiencing problems at work or with friends
addiction
severe with 4+
addiction with either tolerance or withdrawal
with physiological dependence
indicated by either
large doses of substance for the desired effect or
the effects of the drug become less if the usual amount is taken
tolerance
negative physical and psychological effects that develop when a person stops taking the substance or reduces amount
Withdrawal
withdrawal symptoms
muscle pains, twitching, sweats, vomiting, diarrhea, insomnia
when the person becomes delirious, tremulous and has hallucinations that may be visual and tactile
delirium tremens
responsible for alcohol tolerance
liver enzymes
changes in number or sensitivity of GABA or glutamate receptor
abusing more than one drug at a time
polydrug abuse
prevalence of alcohol abuse by ethnicity
asian americans< african americans< hispanic and whites
metabolization of alcohol
1 ounce of 100 proof liquor per hour
factors affecting levels of alcohol in the bloodstream
amount ingested/ time
presence of food in the stomach
weight and body fat
efficiency of the liver
effects of alcohol on the neural system
stimulates GABA ( reduce tension) increase serotonin and dopamine (pleasure) inhibits glutamate receptors (slow thinking, memory loss)
severe loss of memory for both recent and long past events
amnestic syndrome
a disease in which some liver cells become engorged with fat and protein, impeding their function
cirrhosis of the liver
when the growth of the fetus is slowed, and cranial, facial and limb anomalies can be produced due to the consumption of alcohol by pregnant women during pregnancy
fetal alcohol syndrome
Smoke coming from the burning end of a cigarette
secondhand smoke
environmental tobacco smoke
consists of the dried and crushed leaves and flowering tops of a hemp plant
marijuana
cannabis sativa
produced by removing and drying the resin exudate of the tops of cannabis plants
hashish
MJ effects on brain
CB1 receptors in hippocampus
increased blood flow to areas of emotion
decreased blood flow in auditory attention
therapeutic effects of MJ
reduce nausea and loss of appetite in chemo patients
relief for AIDS
a group of addictive drugs that in moderate doses relieve pain and induce sleep
opiates
plant of joy
opium
powerful sedative and pain reliever from opium
alkaloid morphine